Objective:To explore the clinical features of perimesencephalic nonaneurysmal subarachnoid hemorrhage (PNSH).Methods:The clinical manifestation,CT,treatment and prognosis of eighteen cases were analyzed.Results:All patients were conscious,whose Hunt-Hess scale were Grade Ⅰ to Ⅱ.In 18 cases headache developed,15 (83.3%) vomiting,14(77.8%)meningeal irritation,and 2(11.1%) focal neurologic deficits.All patients recovered completely.Conclusion:PNSH is a distinct clinical entity with few manifestations,good prognosis and low rate of severe complications.Repeated angiography should be avoided for PNSH.

Objective:To investigate the effect of Matrine on inhibiting lipopolysaccharide( lipopolysaccharide ,LPS) -induced macrophages to secrete inflammatory cytokines,including tumor necrosis factor-α( TNF-α) ,leukocyte mediated element 1β( IL-1β) on Toll like receptor 4 ( TLR4 ) , c-jun expression. Methods: Cultured macrophage RAW264. 7 of mouse and divided into four groups, including blank control group,matrine group,LPS group,matrine intervention group. Incubated by the concentration was 100 μg/L LPS DMEM for 1 h,then the LPS was discard. Added free serum DMEM or 125. 25 mg/L matrine DMEM to culture. The cells and culture solution of 5,30,60,120 min after the treatment of the above four groups were collected respectively. Detected of mouse RAW264. 7 macrophage TLR4 and c-jun mRNA expression by PCR. Detected of mouse macrophage RAW264. 7 cells c-jun protein expression by immunocytochemical. Measured secretion in cultured solution of TNF-α and IL-1β by ELISA. Results:Expression TLR4 mRNA,c-jun mRNA and c-jun protein and TNF -α and IL-1β secretion quantity indexes of matrine induced and blank group had no statistical significant differences ( P>0. 05 ) . TLR4 mRNA, c-jun mRNA and c-jun protein expression secretion of and TNF-α and IL-1β LPS group at each time point were significantly higher than that of blank group,and the high level to maintain more than 2 h (P<0. 05);matrine intervention group could effectively inhibit LPS induced macrophage TLR4 mRNA,c-jun mRNA and c-jun protein expression and reduce the secretion of inflammatory cytokines TNF-α and IL-1β. Conclusion: Matrine may inhibit LPS induced macrophage mitogen activated protein kinase signal pathway of TLR4 and c-jun expression so that it can effectively reduce the end inflammatory cytokines TNF-α and IL-1β release,effectively inhibit the inflammatory reaction and reduce the degree of endotoxin inflammatory re-sponse.

It is an important goal of the modern medical education to culture the innovative ability of medical students. In the clinic teaching of thoracic surgery, illuminating innovative thinking, optimizing and recombining teaching contents, flexible utilizing of teaching approach and methods, and innovating practical teaching are in favor of creating the innovative thinking and innovative ability of the students.

Quality assurance of EBCT images is especially important in clinic. Factors influencing the quality of images are so variable and complex that comprehensive consideration should be paid to them. The analyses and researches for such factors as surrounding background, machine's inherent property and scanning parameters are made separately.

Objective To verify the usefulness of the corresponding compensation techniques for MRI artifacts after analyzing their generation mechanism. Methods Different compensation techniques were used to eliminate relative artifacts from the angle of improving background,calibrating software and hardware,editing parameters or instructing patients in scanning the patient or phantom with 1.0TMR and 1.5TMR. Results Artifacts were controlled to different extents and the quality of most MR images were improved. Conclusion Most artifacts can be eliminated completely by the use of corresponding compensation techniques while some others only be reduced a little or shifted.

Objective To verify whether it is useful to apply the corresponding preventive measures for the radio frequency(RF) field artifacts in MR images by the research of their influencing factors.Methods Preventive measures were taken according to the factors producing RF field artifacts in MR images.Results Various RF field artifacts in MR images were reduced,shifted or even eliminated completely.Conclusion Most RF field artifacts in MR images can be controlled by the application of the relative preventive measures.

Objective To evaluate the application effect of workload statistic software.Methods According to the actual workflow of the hospital and concrete management index sign,the workload of statistics procedure was designed using Dephi7.0.Results "Comprehensive Management System in Medical Imaging Department" run stable and accurate.What's more,its functions greatly facilitated workload statistics.Conclusion The system plays an important role in excellent workflow,exaltation of work efficiency,reasonable allotment of manpower and material resources,etc.

Objective To evaluate the clinical value of fMRI software.Methods Patients were scanned with the corresponding fMRI software to observe the change of imaging signals in tissue's functional zone.Results The signals in the relative functional zone of tissues varied with their functions.Consulation fMRI software has great value in such clinical applications as tissue physiology,biochemistry and metabolism functions.

Objective To investigate the diagnosis and therapy of Crohn's disease(CD).Methods The clinical data of 30 cases of pathologically proven CD from 1992 to 2005 were analyzed,26 cases were followed up.Results Among the 30 patients with CD,13(43.3%)diagmosed by endoscopy and biopsy.and17 cases(57.7%)were diagnosed by operation and pathology Before operation,6 cases were diagnosed as acute abdomen,4 cases as ileus,3 cases as massive hemorrhage of gastrointestinal tract,2 cases as colorectal cancer,1 case as intestinal fistula and 1 case as head mass of pancreas.Of the 26 cases followed up cases,15 cases accepted operation with 5 cases of recurrence;21 cases have taken drugs,and the total effective rate was 73.1%.Conclusions CD is a chronic relapsing disease and is difficult to diagnose.The majority of patients undergo operation due to misdiagnosis or complications.CD is prone to relapse postoperatively,quality of life is poor,and one must heighten awareness of these patients,make early diagnosis,directed therapy,and intensify follow up.

Objective To find out about the use of anti-infectious agents by tumor outpatients of the hospital. Methods A survey was conducted on 1 011 prescriptions for anti-infectious agents written out in the hospital from October to December of 2003 and an analysis was made of the structure and rationality of their use by means of drug utilization studies. Results The utilization rate of anti-infectious agents was 8.35% , accounting for 1.09% of the total sum of money for the prescriptions. The kinds of anti-infectious agents used were mostly cephalosporins and quinolones. The utilization rate of agents of compatibility was 4.44%. The drug utilization index of some chemicals was close to 1.00, accounting for about 44.44% . Conclusion There is no widespread abuse of anti-infectious agents by the outpatients of the hospital and the utilization rates of anti-infectious agents and agents of compatibility are low. Still, there are some problems in the use and compatibility of certain agents and the rationality of their use is to be questioned. The use of anti-infectious agents should be planned in a scientific way and in line with the economic condition of the patients.