This article reviewed the advances in studies on intestinal absorption characteristics of zinc and possible mechanisms.It has set a foundation for elucidating important functions of zinc absorption in maintaining zinc homeostasis in the body of animals.

Acupuncture Points ; Acupuncture Therapy ; Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Neck Injuries ; therapy ; Young Adult

Objective To evaluatethe application value of APACHE Ⅱ on the prognoses in prediction of pin hole multi-directional intracranial hematoma aspiration to cure severe cerebral hemorrhage.Methods APACHE Ⅱ scoring system was conducted in randomly collected 58 severe cerebral hemorrhage patients' data (30 patients underwent surgical treatment,28 patients underwent conservative treatment)to evaluate the disease severity,prognosis and effect of the pin hole multi-directional intracranial hematoma aspiration.Results The APACHE Ⅱ score of treatment group on the first day was 28.00 ± 1.92 and the predicted mortality was 0.86 ±0.03.The score was decreased obviously on the tenth day(8.20 ± 0.76)and the predicted mortality was 0.57 ± 0.05.The actual mortality was 33.33％.Conclusion APACHE Ⅱ scoring system is suitable for judging the disease severity and predicting the prognosis of severe cerebral hemorrhage patients,it proves that surgical treatment effect of the pin hole multi-directional intracranial hematoma aspiration is remarkable.

Arsenic trioxide (As2O3)is the main component of traditional Chinese medicine arsenic,which was initially used in the treatment of blood system diseases.In recent years,studies have found that it also has a good effect on a variety of solid tumors,especially gastric cancer.It has been confirmed that As2O3 can inhibit proliferation and metastasis of gastric cancer cells,induce apoptosis and protective autophagy,inhibite lymphatic formation and angiogenesis,affect the expression of telomere-related proteins in gastric cancer cells.

Objective To study the relationship between serum homocysteine level and acute type 2 diabetes mellitus complicated with cerebral infarction.Methods Patients were divided into three groups:acute diabetic cerebral infarction group including 87 patients,diabetes mellitus including 72 patients and control group including 67 healthy persons.The HCY,folic acid,VitB12 and serum lipid were determined.The data was analyzed and the relationship was discussed.Results The level of HCY in diabetic cerebral infarction group[(15.7 ±9.7)nmol/L]was much higher than that in the other two groups[(11.9±7.2)nmol/L and(13.5±6.1)nmol/L].Conclusion HCY maybe participate in occurrence and development of diabetes and pathological changes of blood vessels.It was an independent risk factor of acute cerebral infarction.

Docetaxel and vinorelbine, which were plant alkaloids, had showed the good activities as chemotherapy of breast cancer. Combination chemotherapy with docetaxel and vinorelbine had drawn more and more attention. This papers reviewed the docetaxel/vinorelbine combination treatment of breast cancer.

Objective To determine the reversal effect of psoralen on multidrug resistance (MDR) in the harringtonine (HT)-resistant leukemic cell line HL60/HT. Method The modulating effect of psoralen on MDR in HL60 and HL60/HT cells were determined by the measurement of cell growth and viability via MTT assay. High performance liquid chromatography(HPLC) was used to analyze intracellular HT concentrations in HL60/HT and HL60 cells treated with psoralen. Result Psoralen from 1 to 20 μmol/L could reduce the value of IC50 to HT and enhance the accumulation of HT in HL60/HT cells. Conclusion Psoralen can reverse MDR of HL60/HT cells and is a potential modulator of MDR.

Acupuncture Therapy ; Fingers ; blood supply ; Gangrene ; therapy ; Humans ; Male ; Middle Aged

Cardiovascular disease (CVD) is one of the major complications of type 2 diabetes mellitus (T2DM), which results in a high risk of mortality. Thus, the cardiovascular safety of new anti-diabetic agents has become an important prob?lem with wide concern. There are two classes of incretine-based medications: glucagon-like peptide-1 receptor agonist (GLP-1RA) and dipeptidyl peptidase-4 (DPP-4) inhibitor (DPP-4I). It has been demonstrated that GLP-1RA and DPP-4I possesse beneficial actions in both animal models of cardiovascular dysfunction and patients with ischemic heart diseases. However, their effects on the cardiovascular system in diabetic patients with heart diseases are still uncertain. Here, we sys?tematically reviewed the effects of GLP-1RA and DPP-4I on cardiovascular system to provide more evidence of incretin-based therapy application for diabetes and complications.

OBJECTIVE To understand the situation of hand hygiene in our hospital to explore effective measures for implementation.METHODS 258 medical personnel,were investigated for the hand-washing,before and after the implementation of the hands of our health system to compare the nosocomial infection rate.RESULTS The low rate 35.02%~49.42% of medical personnel washed their hands before the normal operation in and out the Ⅱ area.Hand-washing compliance rate was only 54.17%;and after the implementation of our health system in hand,nosocomial infection rate decreased 30%.CONCLUSIONS Washing hands is important to prevent nosocomial infection,Medical personnel generally do not have a strong sense and we should start and strengthen the supervision and improve the supporting facilities to ensure the compliance of medical staff.