1.Positive effects of classification teaching method on motivation
Journal of Chongqing Medical University 2000;25(z1):116-117,120
It is generally agreed that motivation is one of the most important factors influencing the students success or failure in learning a language. Motivation, according to Harmer, is an internal drive that encourages the learner to pursue a course of action(1983: 3). Expressed more colloquially, when students perceive an attractive goal that they wish to achieve, they may do whatever is necessary to reach it. Then they are strongly motivated.This article aims at introducing the classification teaching method into English teaching. Studies suggest that classification teaching method has positive effects on motivation.
2.Detection of Chlamydia trachomatis DNA by gap ligase chain reaction (G-LCR)
Journal of Chongqing Medical University 1987;0(01):-
Objective:To develop a new nucleic amplication method for detection of Chlamydia trachomatis DNA by gap ligase chain reaction(G-LCR).Methods:A G-LCR DNA amplification assay that targeted the outer major membrane protein gene(omp1)of CT was established to detect CT infection.The sensitivity and specificity of a newly developed G-LCR test was examined by the use of highly purified elementary bodies (EBs).DNA fragments of different species and from other bacteria1 were detected with G-LCR and routine polymerase chain reaction (PCR).Results:Using G-LCR,DNA fragments of 54bp were amplified from five different species.The sensitivity could be improved to detect out 2 chlamydial elementary bodies.G-LCR detected ten-fold EBs than PCR.No signal was observed when C.pneumoniae and other bacteria were used as templates.Conclusion:G-LCR is sensitive,rapid and specific for detection of Chlamydia trachomatis.
3.Report of a case with Potter's syndrome.
Chinese Journal of Pediatrics 2004;42(7):556-556
4.Our Opinion on the Execution of the Pharmaceutical Patent Law in China
China Pharmacy 1991;0(04):-
In view of the fact that the Pharmaceutical Patent Law will be put into effect in China,the authors suggest that the development of new drugs in China should be relied mainly rather on creating than on copying. However,some of the effective drugs should be still modelled on foreign products. We should pay great attention to the research work on pharmaceutical preparations and the development of Chinese patent medicine, intermediates of preparation and reagents.
5.Correlation Study on Self-identity,Personality and Mental Health of 188 Medical Freshmen
Hong-Hong XU ; Wei HONG ;
Chinese Mental Health Journal 2002;0(11):-
Objective:To explore the relations between freshmen's self-identity status,personality characteristics and mental health status.Methods:188 new students were asked to complete the questionnaires of mental health scale and personality scale from the China college students mental health evaluation system,and eollnge students self- identity status scale.Results:①the most status of identity is achievement(43.1%),then the identity diffusion (30.9%);②male students in compare with female,were more likely in achievement status(60.7?13.8/53.9?11.4,P0.406);③the achieve- ment status had obvious negative correlation with depression,dependency(r=-0.17~-0.24),the diffusion status had obvious positive correlation with depression,social-withdrawal,and impulsion(r=0.15~0.34);④active,ac- commodating,tough-minded personality characteristics had obviously negative correlation with mental symptoms(r= -0.16~-0.56).Conclusions:encourage college students to form the achievement ego-identity status,to be ac- tive,accommodating and tough-minded,will be helpful for their psychological health.
7.Research progress of mTOR signal pathway effect in cardiovascular system
Chinese Journal of cardiovascular Rehabilitation Medicine 2016;25(2):225-228
Mammalian target of rapamycin (mTOR)is an atypical serine/threonine protein kinase,which is a key protein kinase regulating cell growth,proliferation,translation,metabolism and autophagy.It's first known beca- nuse inhibited by rapamycin.Research indicated that mTOR plays a key regulating role in physiological and patho- logical process of cardiovascular system.The present article mainly reviewed research progress of mTOR signal path- way effect in cardiovascular system.
8.Effect of plastic surgery of double-palpebra with prolapse of lacrimal gland for blepharochalasis
Chinese Journal of Medical Aesthetics and Cosmetology 2014;20(3):186-189
Objective To investigate the clinical effect of plastic surgery of double-palpebra with reposition of lacrimal gland for blepharochalasis.Methods We operated on 10 cases (20 eyes) with dermatolysis palpebrarum which stopped attack and was static for more than one year.A double eyelid fold incision was made.Then redundant skin and sphincter palpebrarum as well as protrusion of intraorbital fat were removed.In the operation of dislocation of lacrmial gland we sewed up lacrmial gland in full thickness and fixed it to the periosteum of lacrmial fossa,and the levator muscle of upper eye lid aponeurosis prothesis or plication was choosed when the levator muscle of upper eye lid aponeurosis was broken or not.And for the shorted transverse diameter of coloboma of eye lid we sewed up the external palpebral ligament and fixed it to the periosteum of lateral orbital margin.Results All the 10 patients got satisfactory therapeutic effect,the cutis laxa had been amended obviously,the good upper double eyelid shape could be achieved,the reposition of lacrimal gland was finished,lapsus palpebrae superioris and shorted transverse diameter of coloboma of eye lid had been rectified satisfactorily.All cases we followed up for three monthes to one year,and dislocation of lacrmial gland had been amended in one case,others had been reposited well,without recurrence.Conclusions Blepharochalasis can be effectively treated by surgery,and it is convenient and effective to treat dislocation of lacrimal gland and blepharochalasis through a double eyelid fold incision.This multiple surgical treatment is not only a curative operation but also a cosmetic surgery.
9.Influence of Prenatal Diagnosis and Immediate Surgery Intervention on the Prognosis of Congenital Hydronephrosis in Children
Journal of Applied Clinical Pediatrics 2004;0(11):-
Objective To explore the influence of prenatal diagnosis,active follow up and immediate surgery intervention on the prognosis of congenital hydronephrosis in children.Methods The clinical data in 85 cases were analyzed retrospectively.They were divided into prenatal diagnosed group and postnatal diagnosed group.Prognostic parameters such as preoperative statuse,pathology during surgery,operation process,status before discharging and complications were collected and statistically analyzed.Results The numbers of grade 4 hydronephrosis,secondary renal calculus,opposite kidney hydronephrosis,preoperative infectioin,perinephric adhesion and postoperative complication in prenatal diagnosed group were significantly lower than those in postnatal diagnosed group(Pa0.05).Conclusions 1.Ultrasonagraphy examination and follow-up are indispensable both before and after delivery which will help doctors to diagnose the disease at early stage.2.Surgical operation on congenital hydronephrosis at early stage is reliable and will achieve the same effect with the children undergo surgical operation at older age.3.Immediate surgical operation is of great clinical significance on preventing serious complication and irreversible kidney damage.
10.Genetic algorithm and support vector machine-based gene microarray analysis
Chinese Journal of Tissue Engineering Research 2010;14(17):3099-3103
BACKGROUND: Gene microarray data has small sample size and large numbers of variates.Traditional statistical method is not effective.Genetic algorithm(GA)and support vector machine(SVM)are machine learning algorithms developed rapidly in recent years,which can decrease the dimension of features.OBJECTIVE: To combine GA and SVM to classify samples and compare with other two processes in which all genes and difference expression genes are taken as classifiers,respectively.METHODS: We applied golub data set provided by Bioconductor,which included gene expression data of leukaemia samples and normal samples.All genes were used to classify samples with SVM.SAM software was used to extract difference expression genes and estimate False Discovery Rate.Finally,76 difference expression genes were used as feature gene set to classify samples with SVM and GA-SVM respectively.Three classification effects were compared.Additionally,the distribution and function about feature genes in KEGG pathways were also discussed.RESULTS AND CONCLUSION: The accuracy of classification of SVM was improved by decreasing dimension with genetic algorithm.In particular,this process eliminated a great deal of redundant genes and noises,which improves the classification performance.Results show that GA-SVM algorithm is effective in classifying samples.In addition,the pathway analysis shows that signal transmission and amino acid metabolism are two major functions of feature genes.