Objective:To analyze the clinical efficacy and safety of amoxicillin and clavulanate potassium in the treatment of chil-dren with suppurative tonsillitis. Methods:Totally 263 children with suppurative tonsillitis from March 2011 to September 2013 in pe-diatrics were randomly divided into two groups, the control group had 130 cases and the treatment group had 133 cases. All the patients were given conventional treatment, meanwhile, the control group was with intravenous infusion of azithromycin, and the treatment group was orally given amoxicillin and clavulanate potassium dispersible tablets. The clinical efficacy, clinical symptom disappearance time and the incidence of adverse reactions of the two groups were observed. Results:After the treatment, the control group were cured with the total effective rate of 83. 8%, and the treatment group were healed with the total effective rate of 90. 2%. The difference wasn't sig-nificant (P>0. 05). Orally used amoxicillin and clavulanate potassium was more economic and convenient, which could reduce the drug-resistance as well. There was no significant difference in the effects on fever, purulent and the white blood cell between the two groups, and no significant adverse reactions showed in both groups. Conclusion:Orally used amoxicillin and clavulanate potassium ex-hibits obvious therapeutic effect on infantile suppurative tonsillitis, which can effectively improve the clinical symptoms without obvious adverse reactions, and it is worthy of clinical use.

Humans ; Occupational Diseases ; Occupational Health

[Objective]To observe the activity of anti-inflammatory and analgesia of Danweisan.[Methods]The analgesia action of Danweisan was determined with twisting method,and the anti-inflammatory effect of Danweisan was evaluated with xylene induced ear tumefaction.The effects of the small,medium,large dosages of Danweisan group(2,3,4g/kg) on twisting and ear tumefaction in mouse were assessed.[Results] Compared with the normal group,it was shown to exert dramatic inhibitory effect with concentration-dependence on mouse twisting and ear tumefaction in the Danweisan group.[Conclusion]Danwesan has a remarkable analgesia activity and a better anti-inflammatory action than asprine.

China ; epidemiology ; Humans ; Occupational Diseases ; epidemiology ; prevention & control

Adolescent ; Adult ; Electrical Equipment and Supplies ; Female ; Humans ; Industry ; Mental Health ; Surveys and Questionnaires ; Transients and Migrants ; psychology ; Young Adult

Myocardial Infarction ; physiopathology ; Myocardium ; Myocytes, Cardiac ; physiology ; Regeneration ; Tissue Engineering

Acetamides ; adverse effects ; Adult ; Alanine Transaminase ; blood ; Aspartate Aminotransferases ; blood ; Case-Control Studies ; Humans ; Liver ; drug effects ; metabolism ; pathology ; Liver Diseases ; epidemiology ; Middle Aged ; Occupational Exposure ; adverse effects ; Young Adult

Objective To research the clinical outcomes of repairing donor site of abdomen flap by V-Y flap pedicled with deep circumflex iliac artery perforator musculocutaneous.Methods Nine cases with skin defects of hand were treated with lower abdomen flap from December, 2011 to March, 2013, abdominal donor sites could not be directly sutured, and pedicled with deep circumflex iliac artery perforator musculocutaneous.The flap was 8 cm × 16 cm-12 cm × 24 cm in size.Results The average healing time of the V-Y flap pedicled with deep circumflex iliac artery perforator musculocutaneous was 17 days.The patients were followed-up for 3 months to 18 months, averaged of 9 months.The appearance and the texture of the flaps were good.Abdominal wound healing was flat, with no significant depression and navel no significant skew.Patients were satisfied with function and appearance.Conclusion This procedure is easy and effective.The treatment result is satisfactory.It is improvement for repairing donor site of tradition abdomen flap.