1.Medical service in high & cold mountainous region in future war
Chinese Medical Equipment Journal 2004;0(09):-
Based on experience on medical service drilling for many years,this paper analyses the hardship and complexity of medical service support in high & cold mountainous region.It also puts forward some suggestions in such aspects as integral design,focal points insurance,necessaries reinforcement,preach for popularization and mutual cure training.
2.A study on the mRNA expression of the glucose transporter gene in the diabetic rats
Chinese Journal of Diabetes 1993;0(00):-
The study was proceeded on the mRNA expression of the GULT1 and GLUT4 gene in the alloxan diabetic rats by the technique of dot-blot hybridization analysis. The results showed that the levels of the GLUT4 mRNA expression were reduced in diabetic rats while increased in insulin treated diabetic rats. This suggests that the reduced GLUT4 mRNA expression which could affect the quantity of its posttranslational products may be one of the causes of the insulin resistance.
3.Review on tissue-engineered trachea research
Basic & Clinical Medicine 2006;0(12):-
The article introduced the recent progress of tissue-engineered trachea.The problems encountered in the field and the study direction in the future are also mentioned.
4.Heat shock protein and cardioprotection
Journal of Medical Postgraduates 2003;0(09):-
The defense mechinism of heat shock protein(HSP)acting as moleculars chaperons requires heat shock transcription factors as the primary mediators of the heat shock response.Increased expression of HSP may protect the heart.Overexpression of HSP can inhibit cardiomyocyte apoptosis,protect the integrity of the microtubules and the actin cytoskeleton in cardiac myocytes and endothelial cells exposed to ischemia,participate in the folding and activation of protein kinases and transcription factors such as HIF-1? and HSF1,bind to endothelial nitric oxide synthase(Enos) and stimulate its activity,and downregulate cytokine production.Hence,it is of benefit to efficiently elevate HSP expression in myocardium using pharmacological and/or gene therapy procedures without any adverse effect.
5.Clinical implications of serum ferritin concentration in patients with impaired glucose tolerance
Journal of Medical Postgraduates 2003;0(06):-
Objective: To investigate the relationship between the serum ferritin concentration and insulin resistance in patients with impaired glucose tolerance(IGT).Methods: The serum ferritin concentration and insulin levels were measured in 40 IGT patients(20 with normal body weight and 20 with obesity),and 40 healthy controls.Blood glucose levels,HbA1C,blood adipose and urine protein concentration were obtained simultaneously.Results: In the IGT patients,the serum ferritin concentration was correlated with Hba1c but not with any other indexes,and it was significantly higher than in the normal controls.Significant differences were observed between the two groups in all the indexes but the fasting insulin level.Conclusion: The serum ferritin concentration increases in IGT patients,which implicates some association of ferritin with glucose metabolism and insulin resistance.
7.Research of procalcitonin in the inflammatory response following cardiopulmonary bypass
Journal of Medical Postgraduates 2003;0(11):-
Procalcitonin (PCT) detection is a diagnostic tool for the differential diagnosis of bacterial or non-bacterial infections complicated by a systemic inflammatory response. Recent research in the cardiac surgery with cardiopulmonary bypass (CPB)suggests PCT level reflect the systemic inflammation following CPB. Measurement of PCT may help to identify the patients with high-risk who may be benefited from specific treatment administered and intensified monitoring provided, so as to reduce the surgical complications.
8.Progress in the migration of vascular endothelial cells and related factors
International Journal of Biomedical Engineering 2006;0(06):-
The migration of vascular endothelial cells plays an important role in the vascular growth, repair of wounds, and repair of vascular endothelial cells. At the same time, the migration of endothelial cells plays an important role in the progress of vascular diseases, especially atherosclerosis. Thus, the characteristics of endothelial cell migration and related factors are very important for us to understand the role of endothelial cells in the progress of physiology and pathology. In this article, the factors of promotion and inhibition, and blood flow, cytoskeleton and extracellular matrix are recommended in details. Furthermore, at the end of the article, we discuss the close relationship between endothelial cells and repair of vascular endothelial cells, even new vascular growth in the plaques of atherosclerosis.
9.Expression of protein inhibitor of activated STAT3 in glioma
Journal of Third Military Medical University 2002;0(12):-
0.05),but existed between grades Ⅰ-Ⅲ and grade Ⅳ(P0.05).Conclusion PIAS3 is expressed in human gliomas,closely correlated with the pathological grade and malignant intensity.PIAS3 may be involved in the development and progression of gliomas.
10.Imaging analysis of cord compression factors in CSM by using MRI motion scan technique
Chinese Journal of Radiology 2000;0(12):-
Objective To study the dynamic etiological effects of degeneration structure in cervical spine with motion MRI image, and to obtain the early diagnosis of CSM. Methods By flexing the patient forward and backward with the joint motion device, a total of 60 cases received MRI study in open MR feature. The motion MRI technique included the multi-angle scan, the joint motion scan, and the MR Fluoroscopy. Results (1) The spinal cord compression due to degeneration structure in flexion-extension was more significant than that in static position, it even had pile up effect. (2) The disc herniation (in 29 cases), the vertebral osteophyte, the segmental instability (in 7 cases), and the thickening of posterior longitudinal ligament (in 36 cases) could cause more serious mixture compression to the cord in anteflexion than in natural position. (3) In extension, the degenerative yellow ligaments (in 34 cases) often folded and encroached upon the spinal canal, which usually formed pincers effect with anterior compression (in 9 cases). (4) The flexion-extension movement could cause lower cervical instability founded in 14 cases. (5) The anterior space of dural sac could be decreased in flexion (in 41 cases) as well as in extension(in 16 cases), and in 43 cases, the posterior space could also be narrowed in extension, but not evident in flexion(in only 4 cases). Conclusion By using the motion MRI scan, the early, potential and dynamic compression factors of cervical spinal cord could be demonstrated not only in shape but also in pathogenesis. So the motion scan can make the diagnosis of CMS earlier than static scan does.