1.Effect of intensified electrocardiogram identification by using spectrogram for the enhancing of monitoring and nursing capacity
China Medical Equipment 2017;14(6):106-108
Objective:To explore the effect of intensified electrocardiogram (ECG) identification by using spectrogram for the monitoring and nursing ability of nurses who worked in department of cardiology.Methods: Monitoring and nursing capacity of 120 nurses of cardiology who had been trained on the intensified ECG identification by using spectrogram were researched by retrospective analysis. The 120 nurses were divided into control group (60 cases) and intervention group (60 cases) as the random number table. The nurses of control group only received routine training of ECG identification, while the nurses of intervention group received the training of using spectrogram for ECG identification on basic routine training of control group. A series of indicators, including the scores of ECG comprehensive application ability, identification ability of abnormal electrocardiogram, and the number of the identified abnormal malignance ECG and successfully treated patients, between the two groups were compared and analyzed.Results: After the training, the scores of basic theory, abilities of description and recording, and analysis ability in field operation of the intervention group were significantly higher than those of the control group, respectively (t=11.896,t=8.596,t=8.283,P<0.05). The identified ability including room speed, atrial flutter, ventricular flutter and other abnormal ECG of intervention group were significantly better than these of control group, respectively (x2=18.836,x2=17.698,x2=16.773,P<0.05). Besides, the discovery rate of abnormal malignance ECG (73.3%) and the successful rate of treatment (100.0%)of intervention group were significantly higher than that (31.7% and 81.7%) of control group, respectively (x2=19.184,x2=10.484,P<0.05). Conclusion:The training of intensified ECG identification by using spectrogram for nurse of cardiology can effectively enhance the capacities of identification for ECG and comprehensive application for nurses, and can faster confirm the situation of patient, and can contribute to achieve precision diagnosis for doctors.
2.A STUCY OF NUTRITION AND FOOD HYGIENE ON THE SUNFLOWER PROTEIN CONCENTRATE AS NEW DEVELOPED FOOD PROTEIN RESOURCE IN HEILONG- JIANG PROVINCE IN CHINA
Acta Nutrimenta Sinica 1956;0(04):-
The sunflower protein concentrate studied in this paper is a new developed food protein resource in Heilongjiang Province. Up to now the studied report on this product has not been seen in China. Using casein as reference protein and soy protein isolate and gluten from wheat flour as comparable substances we studied the content of major nutrients and the composition of essential amino acid in the sunflower protein concentrate by chemical analysis method, and also studied protein efficiency ratio (PER) and other indicators related to nitrogen metabolism in the animal experiment by the recommended method of AOAC. Some common harmful substances in the samples were examined quantitatively. The results showed that the protein content (as anhydrate basic), the PER, apparent digestibility, the true digestibility, the biological value, and NPU of the sunflower protein concentrate were 62.43%, 1.96, 96.83%, 98.51%, 96.81% and 95.35% respectively. The essential amino acid composition was the same as analogous products prepared in other countries. The blood indicators and pathological observation of tested rats were normal. The content of several harmful substances in the product was allowable.All of these results indicated that the nutritional quality of the sunflower protein concentrate is about the same with some similar porducts prepared in other countries. We believe that these products are safe to consumers in the aspect of food hygiene.
3.Glucagon-like peptide-1 based therapy for type 2 diabetes.
Chinese Journal of Pediatrics 2006;44(9):669-671
5.RECENT RESEARCH PROGRESS ON GRASS-ENDOPHYTE SYMBIOSIS
An-Zhi REN ; Yu-Bao GAO ;
Microbiology 1992;0(02):-
Grasses infected by endophytes have an extraordinary impact on the ecology and economy of pasture and turf. In this review, we presented recent research progress on origin and evolution, biological and ecological impact, and perspective of the association in order to make full use of the widely distributed endophyte resources.
7.Advances on PI3K/Akt/mTOR signalling pathway in malignancies.
Chinese Journal of Pathology 2005;34(10):674-676
Antibiotics, Antineoplastic
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therapeutic use
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Apoptosis
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Cell Cycle
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Humans
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Neoplasms
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drug therapy
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metabolism
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pathology
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Neovascularization, Pathologic
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etiology
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Phosphatidylinositol 3-Kinases
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metabolism
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Protein Kinases
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physiology
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Proto-Oncogene Proteins c-akt
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metabolism
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Signal Transduction
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Sirolimus
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therapeutic use
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TOR Serine-Threonine Kinases
8.Research progress of endoplasmic reticulum stress in diabetic cardiomyopathy
Chinese Pharmacological Bulletin 2017;33(9):1200-1203
Diabetic cardiomyopathy(DCM) is a disease independently related with coronary artery atherosclerotic heart disease, hypertensive heart disease, valvular heart disease, congenital heart disease and other heart diseases that are uniquely associated with diabetes mellitus, and the pathological manifestations of DCM are mainly myocardial hypertrophy, interstitial fibrosis, necrosis and apoptosis.Endoplasmic reticulum is the central location of many important cellular functions, and endoplasmic reticulum swelling and functional disorder in diabetic cardiomyocytes, high blood sugar can cause endoplasmic reticulum stress, suggesting that endoplasmic reticulum stress(ERS) may be involved in the pathogenesis of diabetic cardiomyopathy and development.Based on this, this paper summarizes the progress of ERS in diabetic cardiomyopathy from the pathogenesis of diabetic cardiomyopathy, unfolding protein reaction and the related role of ERS in DCM.
9.Research Progress in Cofactor Engineering of Xylose Metabolism in Recombinant Saccharomyces cerevisiae
Jin HOU ; Yu SHEN ; Xiao-Ming BAO ;
China Biotechnology 2006;0(02):-
Cofactor engineering, a vital part of metabolism engineering, changes the redox cofactor regeneration approach. Its main goal is to rebuild the components of metabolic products. The bioconversion of xylose for the production of ethanol is being studied intensively because ethanol is an alternative energy source and a potential liquid fuel. Saccharomyces cerevisiae has been traditionally used in producing ethanol from fermentable sugars but it cannot utilize xylose, only its isomer xylulose. Introduction of the xylose fermentation pathway from Pichia stipitis into S. cerevisiae enables xylose utilization in recombinant S. cerevisiae, but the ethanol yields of xylose fermentation with recombinant S. cerevisiae has been low and large amounts of the byproduct xylitol are produced. The major reason is that the catabolism of xylose with the fungal pathway leads an imbalance of redox cofactor. The process of the catabolism of xylose requires NADPH and NAD~+, both of which have to be regenerated in separated processes. More and more attention has therefore focused on the redox cofactor balance in S. cerevisia. The research progress of cofactor engineering to solve the imbalance of redox cofactor in xylose metabolism recombinant S. cerevisiae was introduced. This included expression of transhydrogenase, increasing the utilization of NADPH, and achieving the anaerobic reoxidation of NADH. Reversing the cofactor specificity of enzymes is another effective way.
10.Detection and Quantification of the Endophyte in Lolium perenne L.
Dan SU ; An-Zhi REN ; Yu-Bao GAO ;
Microbiology 1992;0(05):-
A PCR assay used for detection and quantification of Neotyphodium lolii in tissues of the grass Lolium perenne L. was developed. Compared with the Microscopic analysis of stained tissues, this method was more accurate. For quantitative applications, real time PCR was used to quantify Neotyphodium lolii in Lolium perenne L.. The results showed that there were some variations between different individuals, but no variance existed between different tillers from the same plant. Thus it can be concluded that fungal content in the plant is not only associated with species/variety specific, but also with the genotype of the host plant as well.