6.Treatment of Angina Coronary Artery Disease of 30 Cases with Self-made Huoxue Kuanxiong Decoction
International Journal of Traditional Chinese Medicine 2008;30(2):133-134
Objective To observe the effect of Huoxue Kuanxiong decoction on symptoms and Electrocardiogram changes of angina coronary artery disease.Methods 60 patients were randomly divided into treatment group and control group.Patients in the treatment group were treated by Huoxue Kuanxiong decoction,with one preparation daily for twice uses.Patients in the control group were treated by Isosorbide Mononitrate,20mg,12Qh.The therapeutic course for both groups was four weeks.Results In the treatment group,the distinct effective rate and the total effective rate were 20.0%and 86.7%respectively for angina coronary artery disease,and 16.7% and 76.7% respectively for electrocardiogram.In the control group,The distinct effective rate and the total effective rate were 16.7% and 53.3% respectively for angina coronary artery disease.and 13.3% and 46.7% respectively for electrocardiogram.Conclusion Huoxue Kuanxiong decoction is effective to the patients of angina coronary arterary disease.
7.Observation on the Efficacy of Acupuncture plus Cognitive Function Training in Treating Parkinson's Disease Dementia
Shanghai Journal of Acupuncture and Moxibustion 2016;35(9):1053-1055
Objective To observe the clinical efficacy of acupuncture plus cognitive function training in treating Parkinson's disease dementia.Methods Sixty Parkinson's disease dementia patients were randomly allocated to a treatment group and a control group, 30 cases each. The treatment group was intervened by acupuncture plus cognitive function training, and the control group by conventional drug treatment. The Mini-Mental Status Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) were recorded in the two groups before and after the treatment. The therapeutic effects were compared between the two groups.Results The MMSE score and MoCA score were significantly changed after treatment in the two groups (P<0.05). There were significant post-treatment differences in the MMSE score and MoCA score between the treatment group and control group (P<0.05). The total effective rate was 90.0% in the treatment group versus 70.0% in the control group, and the difference was statistically significant between the two groups (P<0.05).Conclusions Acupuncture plus cognitive function training can effectively improve the symptoms of Parkinson's disease dementia.
8.Hospitals should Enhance Conceptual Cultivation of Humanistic Care for Doctors
Chinese Medical Ethics 1994;0(05):-
The ever tenser physician-patient relationship has been a heated social issue presently.Medical disputes are mainly solved by traditional means of justice or government administration.However,the lack of humanistic care in mediation means can not fundamentally prevent physician-patient disputes,but just pushes doctors to subjectively avoid professions risks,which would affect the application of medical and health measures into real force.Hospital's humanistic care for doctors is not to meet the requirement for their mental health,but for the harmonious development of hospitals and the whole society.Therefore,hospitals should carry out domestic decision-making and management,provide more humanistic care for doctors,and pay more attention to the continuing education and communicating skills of doctors,so as to relive doctors from severe mental pressure,and accelerate harmonious development of hospitals and the whole society.
9.Pharmacokinetics of Compound Amlodipine Besylate/Atorvastatin Calcium Tablets in Healthy Volunteers after Oral Administration of Single Dose vs. Multiple Doses
China Pharmacy 1991;0(02):-
OBJECTIVE:To study the pharmacokinetics of compound amlodipine besylate/atorvastatin calcium tablets(CABACT) following oral administration of single dose vs. multiple doses in healthy volunteers. METHODS:10 volunteers were administered a single dose of Compound amlodipine besylate/atorvastatin calcium tablets(10 mg,p.o.)or multiple doses(10 mg?d-1,p.o.) for 7 days,respectively. Plasma concentrations of amlodipine besylate and atorvastatin calcium were determined by LC-MS/MS and the pharmacokinetic parameters were calculated using DAS software. RESULTS:In single-dose study the pharmacokinetic parameters of amlodipine besylate vs. atorvastatin calcium were as follows:t1/2?(53.4?12.9)h vs.(15.4?4.6)h; Cmax(6.7?1.8)?g?L-1 vs.(18.5?4.4)?g?L-1; AUC0～120 (298.8?97.1)?g?h?L-1 vs. (118.3?48.9)?g?h?L-1; AUC0～∞(412.2?131.5) ?g?h?L-1 vs. (120.0?55.1)?g?h?L-1. In multiple-dose study the pharmacokinetic parameters were as follows:t1/2(49.5?10.3)h vs. (14.4?5.3)h; Cmax(8.7?2.5)?g?L-1 vs. (20.3?5.8)?g?L-1; AUC0～120(451.2?127.1)?g?h?L-1 vs. (136.3?54.9)?g?h?L-1; AUC0～∞(569.3?165.8) ?g?h?L-1 vs. (139.0?61.3)?g?h?L-1; Cav(2.7?0.6)、(8.3?1.3)?g?L-1; R(1.7?0.4) vs. (1.1?0.2). CONCLUSION:The elimination rates of amlodipine besylate and atorvastatin calcium do not change after oral administration of multiple doses of CABACT while slight accumulation of amlodipine besylate is founded.
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