BACKGROUND:The androgen response to resistance exercise is one of hot topics in sports science research. At present, the androgen responses to resistance exercise show different results. There are different androgen changing trends under different resistance exercise interventions.
OBJECTIVE:To have a deep insight into the influence of resistance exercise on the response of human body androgen, clarify research progress in androgen response to resistance exercise, and provide the basic theory for monitoring resistance training.
METHODS:Literatures and paper reports about androgen response to resistance exercise are electronical y retrieved from the American Biological Medical Literature Database PubMed from 1986 and 2013. Final y 46 literatures addressing the research progress is analyzed about androgen responses to resistance exercise were included.
RESULTS AND CONCLUSION:Studies have shown that, weight lifting (power snatch and power clean), squating, and deadlifting produced higher testosterone levels than the smal muscle groups. Under the same load, eccentric and concentric contractions produced the same hormone response. Adequate training amount and intensity may change the circulating testosterone levels. Short sports intermittent time led to a higher testosterone response than the long intermittent time. The free testosterone levels in youth group were significantly increased compared with the older group before and after exercise. Nutrition intervention affected acute testosterone responses to resistance exercise. Changes in exercise intensity and amount wil alter quiet testosterone levels, once returned to normal training, testosterone levels wil return to baseline values. Resistance exercise can increase androgen receptor content in human skeletal muscles.

BACKGROUND: Effect of exercise training on ultrastructure of skeletal muscle is a focus of quantified cytobiology in sports medicine. OBJECTIVE: To explore the changes of transportation function of calcium ion in sarcoplasmic reticulum of muscle in the model of reduced training after endurance training. DESIGN, TIME AND SETTING: The randomized animal trial was performed at Xi'an Sports Institute from April to July 2006, and the biochemical test was performed at the Animal Experimental Center of Xi'an Jiaotong University in July 2006. MATERIALS: Thirty-nine healthy 2-month-old male SD weighing (220?20) g were selected. METHODS: Five rats were used in the preliminary experiment, and the others were randomly divided to normal control group (n=8), endurance training group (n=8) and reduced training group (n=18). The increasing training period of endurance training group and reduced training group lasted for 6 weeks, and then reduced training group was randomly divided to 3 groups according to reduced training cycle: 2, 4 and 6 weeks group. The rats did increasing endurance loading exercise on a treadmill, while reduced intensity was used in reduced training group. MAIN OUTCOME MEASURES: Enzyme coupling method and fluorescence probe technology were used to detect sarcoplasmic reticulum Ca2+-ATPase (adenosine triphosphatase) and maximum Ca2+ uptake and release of gastrocnemius muscle. RESULTS: The activity of Ca2+-ATPase in endurance training group was significantly increased compared with normal control group (P 0.05); reduced training 4 and 6 weeks groups were significantly reduced compared with endurance training group (P 0.05); while the maximum uptake and release of Ca2+ in sarcoplasmic reticulum of reduced training 4 and 6 weeks group was significantly reduced (P

AlM: To investigate the risk factors of diabetic retinopathy ( DR) in type 2 diabetes patients.METHODS:A total of 380 cases of type 2 diabetes were selected from January 2014 to June 2014, divided into DR group (126 cases) and non-diabetic retinopathy ( NDR) as control group (254 cases), all patients were underwent medical history, physical examinations, laboratory and assistance examinations. The prevalence and single factor and multiple factors of DR were analysed by the logistic regression model.RESULTS: The univariate logistic regression analysis showed that DR was associated with diabetes duration, systolic blood pressure, triglyceride, total cholesterol, low - density lipoprotein, urine protein, intraocular pressure, carotid intima - media thickness, peripheral neuropathy disease was the related risk factors for DR. ln multiple logistic regression analysis, only duration was the related risk factors for DR.CONCLUSlON:The occurrence of DR is the outcome of combined action of multiple factors, duration is an independent risk factor for occurrence of DR.

Chronic obstructive pulmonary disease(COPD) is a common condition among the old,which remains a main cause of death due to its high fatality.Airway remodeling is one of its pathological features.This article reviews the pathological changes and imageological assessment of COPD airway remodeling,its correlation with microbes and its pathogenesis and therapies.

Percutaneous balloon pulmonary valvuloplasty has replaced surgery as the first choice for pulmonary valve stenosis,especially for the isolated ones in children.However,there still happen to be some complications which could lead to a bad prognosis or even death,when the procedure has already been a recognized safe one.This paper reviews these complications with their causal factors as well as the ways to prevent and treat them.

Objective To investigate the influence of chiropractic therapy on the growth and intellectual development of 6 months infants.Methods 160 cases of 1-month-old full-term normal infants were divided into the chiropractic therapy group and the control group,each group contained 80 samples.Chiropractic therapy was given to the chiropractic therapy group daily.The development of weight,length,head circumference were observed,and the intelligent development for two groups were evaluated at the age of 6 months.Results The weight,body length in the chiropractic therapy group at the sixth month were higher than those in the control group.The intellectual development in the chiropractic therapy group was also higher than that in the control group.Conclusions Chiropractic therapy plays a significant role in promoting the physical and mental development of babies of 6 months,which is worth being promoted.

Objective To evaluate the therapeutic effect of rituximab combined with autologous peripheral blood stem cell trans-plantation(APBSCT)in treatment of aggressive or refractory and recrrent B-cell non-Hodgkin′s lymphoma.Methods Forty-four patients with aggressive or refractory and recrrent B-cell non-Hodgkin′s lymphoma and treated with APBSCT in this department from Janauary 2007 to October 2013 were admitted.All the subjects were divided into 2 groups according to their own choice:22 pa-tients received rituximab treatment(treatment group)and 22 patients were treated without rituximab treatment(control group).For patients in treatment group,rituximab was used with chemotherapy or mobilization of stem cells before APBSCT for (2.9±1.1) times.After transplantation,IL-2 was used in both groups as maintenance treatment.And rituximab was used in the treatment group if the budget allows.Results The mononuclear cell count in treatment and control group was (13.01±4.22)×108/kg and (11.63±2.95)×108/kg(P=0.214).Hematopoietic reconstruction was successfully achieved in the both groups.No significant difference was found between 2 groups on the recovery time of neutrophilic granulocytes and platelets(P>0.05).All patients a-chieved complete remission(CR),at a median follow-up of 20 months(2-73 months),the disease relapsed in 2 patients in treatment group and 5 in control group.The 2-year overall survival rate in treatment group and control group were 95.0% and 75.1%,2-year progression-free survival rates were 82.4% and 74.5%,there were no significant difference between two groups(P=0.179, 0.393).Conclusion Rituximab combined with APBSCT in treatment of aggressive or refractory and recurrent B-cell lymphoma is feasible,however whether patients can benefit from long-term studies still need further research.Adding rituximab does not affect the hematopoietic stem cell collection and hematopoietic reconstitution.

Renal failure is a common clinical feature in multiple myeloma (MM). The overall remission rate is 35 %-50% (complete remission is rare) in MM patients with renal failure treated by conventional chemotherapy. Many centers use high dose chemotherapy and autologous stem cell transplantation (ASCT) for the treatment of MM patients with renal failure. The current study showed that the severity of renal function damage and dialysis had no impact on stem cell mobilization and implantation. High dose melphalan and ASCT could increase the rates of complete remission, event free survival and overall survival to 30 %, about 20 and 40 months longer, respectively and some patients discontinued dialysis. However there are many problems in this area, such as a higher treatment related mortality leaded by APBSCT. In addition, the role of new agents, such as thalidomide, bortezomib and lenalidomide, require evaluation in MM patient with renal failure.

Tuina manipulations were used on the whole body to treat the sick children with cerebral palsy. In the treatment of total 50 cases of cerebral palsy, after three courses of the treatments, limb paralysis was improved in 35 cases and retarded intelligence was improved in 30 cases. The clinical observation showed that the therapeutic effect was better in the infants below two years old.

Objective:To observe the therapeutic efficacy of superficial needling in treating hemifacial spasm.
Methods:Eighty patients with facial spasm were randomized into two groups by the random number table, 40 cases in each group. The observation group was intervened by superficial needling at local Ashi points and wrist-ankle acupuncture at the Upper 1, Upper 2 and Upper 3 points; while the control group was by ordinary acupuncture. For both groups, the treatment was given once a day, 7 times as a treatment course, and the therapeutic efficacy was evaluated after 3 courses.
Results:The total effective rate and recovery rate were respectively 97.5% and 57.5% in the observation group versus 85.0% and 37.5% in the control group, and the differences were statistically significant (P<0.05).
Conclusion:Superficial needling can produce a more significant efficacy in treating hemifacial spasm than ordinary acupuncture.