Evidence-based medicine,personalization,standardization are the three common sense of cancer care in the 21st century.The model of cancer treatment has changed from experience-guided treatment into gene guided personalized treatment.Recently,personalized treatment of cancer develops fast,particularly in molecular profile for prognosis,molecular marker for efficiency of target drug and so on.

There has been controversies on whether using intravenous or intraarterial thrombolytic therapy around the onset of acute ischemic stroke within 3 hours.This article summarizes the main arguments of different neurologists.

dence is weak. And whether it is ethical to have a placebo arm in reperfusion trials in the 3- to 6-hour time window remains controversy. This article discusses them.

Carotid artery and coronary atberosclcrotic lesions often coexist. How to manage the two kinds of lesions, especially to reduce the risk of perioperative stroke, whether it is necessary to treat carotid artery lesions first or simultaneously before coronary artery bypass grafting, and whether stent angioplasty can replace carotid endarterectomy in the treatment of carotid disease has been controversial. This article discusses them.

ObjectiveTo explore clinical manifestations and CT performance characteristics of amalgamative AIDS tuberculosis. MethodsThe clinical data and CT manifestations of 28 patients who were already diagnosed with AIDS amalgamative tuberculosis were analyzed. ResultsThe common clinical manifestations of AIDS amalgamative tuberculosis: were cough, sputum, fever, night sweats, angular, difficult breathing, diarrhea, superficial lymph node enlargement,etc. The CT manifestations:were diffuse com grain of venereal change, the spot piece infiltrating kitchen,lung door ormediastinumlymphnodeenlargement, pleuraleffusion. Emptyandcalciticationwererare.ConclusionThe clinical manifestations and CT performance characteristics of amalgamative AIDS tuberculosis were not typical,whose performance was related with the body's immune state. When AIDS patients appoare diffuse lung in corn grain, spot piece infiltration sex pathological change focal, lung door or mediastinum lymph node enlargement, the possibility of amalgamative tuberculosis pleural effusion should first be diagnosed.

Neuroimaging studies show that transient ischemic attacks of middle cerebral artery occlusion are not uncommon.Whether these patients should be treated with tissue plasminogen activator remains to be controversial.This article introduces the different views around this debate.

ObjectiveObserving the distribution and the change of the quantity of SP,VIP in the colon tissue of 'cathartic colon'rats.MethodsWe divided the 32 wistar rats weighted (200 ±10)g into 2 groops randomly:the blank group( n =8) and model group( n =8).we induced the 'cathartic colon'rats with the suspension of dahuang.The blank group were given the distilled water for contrast.After one week during the time Dahuang was stopped.We killed them,measured the carbon powder propulsion rates in the intestine and then took Specimen after the 8 rats were fasted 24 hours as well as the blank group,but water were given.We compared the variation of SP,VIP distribution between two groups.ResultsThe carbon powder propulsion rates in the model group were slower than that in the saline control group.The distribution of SP,VIP are all more than that in the blank group.ConclusionThe distribution of SP,VIP are all more than that in the blank group.

ObjectiveTo study and compare the nursing effect of different nursing modes in patients with dysuria after transurethral electrovaporization of the prostate. Methods50 patients with dysuria after transurethral electrovaporization of the prostate from January 2007 to March 2011 were selected as research objects,and they were randomly divided into group A and group B with 25 cases in each group,group A was taken care with routine nursing method,group B adopted evidence-based nursing mode,then the rate of self- maturate,usage rate of catheter,time of indwelling catheter,maximum flow rate,relapse of dysuria,satisfaction degree,treatment compliance and quality of life before and after the nursing of two groups were analyzed and compared. ResultsThe rate of self-maturate and satisfaction degree of group B were higher than those of group A,usage rate of catheter and relapse of dysuria were lower than those of group A,time of indwelling catheter was shorter than that of group A,treatment compliance and quality of life were all better than those of group A,there were significant differences. ConclusionsThe nursing effect of evidence-based nursing mode in patients with dysuria after transurethral electrovaporization of the prostate is good,it can significantly improve the quality of life and is popular among patients.

There are many controversies for how to treat the occurrence of ischemic stroke on the basis of infective endocarditis would be more reasonable,especially there is no consensus on whether to treat with anticoagulants.The article discusses about this.

Livin and Fas-FasL can inhibit cell apotosis. Recent studies show Livin is overexpressed in lung cancer and promotes tumor development. Fas -FasL is expressed abnormally in lung cancer. Aberrant expression of Livin and Fas-FasL may play synergetic roles in lung carcinogenesis, and may be new targets for diagnosis and gene treatment of lung cancer.