3.Clinical study of senile acute cholangitis severe type in old man
Chinese Journal of Primary Medicine and Pharmacy 2008;15(2):228-229
Objective To explore the clinical study of surgical treatment of the senile acute cholangitis severe type in old person.Methods According to the relationship between the senile pathophysiologic characteristics and senile acute cholangitis severe type(ACST),83 patients were selected to the study.Results In operation group with which included 83 cases,4 cases were died,the total mortality is 5.0%.Rate of remnant stone is 15.0%.Ulcer was healed in 79.0%,significantly improved in 14.0%and poor in 9.0%of patients.Conclusion When conditions turned to be stable,operation should be done in time.The main Causes of death of senile ACST are the delay of operation,severe complications and old man.
4.Clinical study on 51 cases of gallstone ileus
Chinese Journal of Primary Medicine and Pharmacy 2008;15(z1):22-23
Objective To explore the characteristics of treatment of gallstone ileus.Methods According to the relationship between the senile pathophysiologic characteristics and senile acute cholangitis severe type(ACST),83 patients were selected to analyze.Results In operation group,which included 83 cases,4 cases were died,the total mortality is 5%.Rate of remnant stone is 15%.Ulcer was healed in 79%.significantly improved in 14% and poor in 9% of patients.Conclusion When conditions turned to be stable.operation should be done in time.The main causes of death of senile ACST are the delay of operation,severe complications and old man.
5.Study of genistein on human breast cancer cells of estrogen-like activity
Journal of Chinese Physician 2008;10(12):1631-1633
Objective To explore the role of genistein (genistcin, GEN) on human breast cancer cell proliferation and its mecha-nism. Method GEN MTT method was used to detect the proliferation of GEN on estrogen-dependent breast cancer cells MCF-7 and non-es-trogen-dependent breast cancer cell proliferation of MDA-MB231. Estrogen receptor.antagonist IC1182780 was used to observe the effect of GEN. FACS was used to analyze the cell cycle of breast cancer cells. Results GEN promote MCF-7 cell proliferation, and make G1/S transition. Estrogen receptor antagonist can block the proliferation effect on MCF-7 cells but no effect on MDA MB231. Conclusion GEN has estrogen-like activity, which was mediated by estrogen receptor (ER).
6.Endovascular treatment of long femoro-popliteal arterial occlusions of lower extremities
International Journal of Surgery 2009;36(8):516-518
Objective To explore the feasibility and outcome of percutaneous transluminal angioplasty (PTA) as a primary treatment modality long femoro-popliteal arterial occlusions in critical limb ischemia.Methods Ten cases with 10 lesions in their femoro-popliteal arterial occlusions were treated with PTA, and the symptoms, intraoperative and postoperative DSA characteristics were retrospectively analyzed. Short-term follow-up were obtained in 8 cases. Results The technical success rate related to procedure was 90% and 12 stents were placed after PTA in femoro-popliteal arterial occlusions. One case was suffered fromamputa-lion due to development of compartment syndrome. The primary patency rate and recurrence rate of 12 months after procedure were 70% and 30% respectively. Conclusion Patients with critical limb ischemia could be beneficial from PTA in long femoro-popliteal arterial occlusions.
8.Clinical Observations on Heat-sensitive Point Medicinal Moxibustion for the Treatment of Lumbar Intervertebral Disc Herniation
Shanghai Journal of Acupuncture and Moxibustion 2015;(12):1219-1220
ObjectiveTo compare the clinical efficacies of heat-sensitive point suspended moxibustion versus heat-sensitive point medicinal moxibustion in treating lumbar intervertebral disc herniation.MethodSixty patients with lumbar intervertebral disc herniation were randomly allocated to treatmentand control groups, 30 cases each. The treatment group received heat-sensitive point medicinal moxibustion and the control group, heat-sensitive point suspended moxibustion. The lumbar vertebra JOA score was recorded before and after treatment.ResultThe lumbar vertebra JOA score decreased significantly in both groups of patients after treatment (P<0.05). There was a statistically significant post-treatment difference in the lumbar vertebra JOA score between the treatment and control groups (P<0.05). There was a statistically significant difference in the total efficacy rate between the two groups (P<0.05).ConclusionThe results show that the lumbar vertebra JOA score decreased in both groups after treatment. The total efficacy rate of heat-sensitive point medicinal moxibustion is superior to that of heat-sensitive point suspended moxibustion in treating lumbar intervertebral disc herniation.
9.Investigate the improvement of quality standard on eight-positive particles
Chinese Journal of Biochemical Pharmaceutics 2014;37(4):164-168
Objective To improve the content determination of eight-positive particles,and better control drug quality.Methods Gardenin, emodin and chrysophanol of eight-positive particles were determined by HPLC.Revised content determination standards and improved the standards of quality control. Results The revised content determinations of gardenin, emodin and chrysophanol were simple and feasible, and had high sensitivity.Conclusion Unification the quality standards of eight positive granules,the standards provide the basis for standardizing the market of eight-positive particles.
10.Dr. Chang Qing's Experience in Treating Refractory Asthma
Journal of Zhejiang Chinese Medical University 2015;(7):523-524
Aim] To summarize and introduce the clinical experience of Chang Qing in the treatment of refractory asthma. [Method] To analyze the clinical experience and academic views of Chang Qing in the treatment of refractory asthma from the perspective of etiology and pathogenesis; and to discuss his basic prescription compatibility and flexible drug-applying characteristics. [Result] According to Chang Qing's clinical experience, while addressing the symptoms, treating the root is badly needed. He insists that in the period of acute exacerbation the adjustment of traditional Chinese medicine dosage should be used to rapidly bring the asthma under control until the symptoms disappear or obviously ease, then nourishing spleen and kidney to reduce the relapse of asthma. [Conclusion] In the aspect of treating the refractory asthma, Chang Qing has got rich clinical experience and effective. methods to relieve the asthma,his clinical dialectic thinking and the originality of prescription are greatly worth learning.