Objective To investigate the state of self-perceived burden (SPB) and depression and to explore the relationship between them for patients with chronic respiratory diseases.Methods 95 patients with chronic respiratory diseases were investigated by the Self-Perceived Burden Scale (SPBS) and Self-Rating Depression Scale (SDS).Results The average score of SPBS was (33.64±10.23) points,which was at the middle level,90.5％ of patients showed different levels of burden,and 34.7％ of patients were at the high level.The average score of SDS was (50.23±11.93),the index was 0.63,which was at the middle to high level,74.7％ of patients showed different levels of depression,and 33.7％ of patients were at the high level.There was a positive conrelation between SPB and depression.Conclusions Patients with chronic respiratory diseases had obvious SPB and depression,and there was a close relationship between them.With chronic respiratory diseases breaking out repeatedly and more severe year by year,most patients have high level of burden and negative emotions.Nurses should take proper measures and psychological interventions to help patients face to the diseases optimistically,and to improve patients' emotion state and enhance their physical and mental health.

The paper discusses whether to maintain nonhealthy foetus,the bearing control of patients with hereditary diseases,the aim to apply the technique to distinguish foetus' sex and personal morals and social ethical problems for health staff to do that,points out that the technique can be applied only to check hereditary diseases as to be benefit to bearing good child and arising people's quality ,and the techique should be controlled properly as not to serve for feudal ethic.

Alzheimer Disease ; pathology ; Drugs, Chinese Herbal ; pharmacology ; Humans ; Rhodiola

With the wide application of Chinese herbal medicine, herb-drug interaction (HDI) has become increasingly prominent. Metabolic enzymes and transporters are the main targets of HDI, because the changes in expression and function of enzymes and transporters can influence the disposition of drugs. Metabolic enzymes are responsible for the metabolic clearance of drugs, including cytochrome P450 (CYP), UDP-glucuronyl transferase (UGT) and sulfotransferases (SULT); transporters widely expressed in the intestine, kidney, liver and brain are involved in the oral absorption, distribution and excretion of drugs. Pueraria, ginkgo, ginseng, St. John's wort and other Chinese herbal medicine often induce a HDI because those herbal medicines combined with chemical medicine are widely used in clinic. The components of herb medicines mentioned above are prone to interact with enzymes and transporters, which often induce a HDI. This paper reviews the advances in the study of enzymes and transporters-mediated pharmacokinetic mechanism of HDI.

Ovarian cancer is highly lethal despite multiple therapies, and new therapies are therefore needed.Retinoids are potential anticancer drugs that can promote apoptosis,inhibit growth and induce differentiation in cancer cells,and all these functions are regulated by the expression of retinoid receptors.Herein the recent researches on the expression of retinoid receptors in ovarian cancer are reviewed.

Health Personnel ; Humans ; Infection Control ; Infectious Disease Transmission, Patient-to-Professional ; Occupational Diseases ; prevention & control

In order to get the adaptive bandwidth of mean shift to make the tumor segmentation of brain magnetic resonance imaging (MRI) to be more accurate, we in this paper present an advanced mean shift method. Firstly, we made use of the space characteristics of brain image to eliminate the impact on segmentation of skull; and then, based on the characteristics of spatial agglomeration of different tissues of brain (includes tumor), we applied edge points to get the optimal initial mean value and the respectively adaptive bandwidth, in order to improve the accuracy of tumor segmentation. The results of experiment showed that, contrast to the fixed bandwidth mean shift method, the method in this paper could segment the tumor more accurately.
Brain Neoplasms ; pathology ; Contrast Media ; Humans ; Magnetic Resonance Imaging ; Neuroimaging ; Skull

Australia is a country with strict drug administration, which is hard for its market access. Chinese Medicine Registration Act 2000 enacted by Victoria State of Australia established the legal status of traditional Chinese medicine in Victoria State, which made Australia the first one of western nations to legislate traditional Chinese medicine. We should take advantage of this opportunity to give in-depth analysis of laws and regulations on traditional Chinese medicine in Australia to push on traditional Chinese medicine to enter the Australia market. By analyzing the regulations of traditional Chinese medicine in Australia market, we put forward the following strategies on traditional Chinese medicine accessing Australia market: first, we should strengthen cooperation of Chinese and Australian governments; secondly, we should focus on analysis of regulations of drugs of Australia, thirdly, we should establish technical standard of herbal drugs in conformity with international standard; finally, we should strengthen traditional Chinese medicine culture exchange.

We analyzed and sorted the policies and regulations of traditional medical management in international markets which also affecting traditional Chinese medicine and summaried current situation of barriers of policy and regulation of Ttraditional Chinese medicine.After thoroughly analyzing the reasons of barriers of policy and regulation of traditional Chinese medicine,we found that the reasons lied in culture difference between China and western countries,quality of traditional Chinese medicine,low level of R&D and manufacturing,incomplete domestic laws and regulations of traditional Chinese medicine,lack of anti-technical barriers to trade service system.In the end of this paper,we came up with some countermeasures of barriers of policy and regulation when traditional Chinese medicine accessing international markets.

MicroRNA(miR)-203 is a stemness-inhibiting miRNA that adjusts the epithelioid cell differentiation by restricting the expression of stemness-related transcription factor.Its abnormal expression has been detected in several types of human cancers,including bladder cancer,breast cancer,colon cancer and pancreatic cancer.miR-203 plays a critical role in the tumor genesis and development by regulating cell proliferation,differentiation and apoptosis.