Parents and family background cast important influence on children's attachment style. Studies have consistently showed positive relations between maternal sensitivity and infant attachment security. Warm and harmonious family was also found to be an important factor. On the contrary, parents' poor marital status and high level of stress in family would result in insecure attachment style in children.

Magnetic resonance imaging (MRI),a commonly used imaging technique,has been extensively investigated in lung cancer diagnosis and staging.Many studies have demonstrated that MRI can be used for the differential diagnosis of benign and malignant pulmonary nodules and for the screening of lung cancer; it also has important value in TNM staging of non-small cell lung cancer (NSCLC),with equivalent sensitivity and specificity to 18F-fluorodeoxyglucose (18F-FDG) PET-CT,which suggests that MRI can be used as an alternative imaging modality in noninvasive diagnosis and staging of NSCLC.

The knowledge atlas for researches of invisible knowledge management was plotted after the key words and their relationship in papers on invisible knowledge published in the past 5 years were quantitatively and qualitatively analyzed by social network analysis, co-words cluster analysis, and impact factor analysis with the journal articles covered in CNKI, Wanfang, VIP Chinese Scientific and Technological Journals Databases as the data source.The hotspots and structure in researches of invisible knowledge management were then studied in order to provide reference for the innovative development and future research of invisible knowledge management.

Objective To investigate the status of professional identity of Xinjiang nursing students and analysis on the differences in different nations and educational levels, so as to provide the basis for nursing professional identity education. Methods By cluster sampling,a total of 626 nursing students of two schools in Xinjiang were surveyed by general information questionnaire and the Professional Identification Scale for nursing students. Results Theprofessional identity level of Xinjiang nursingstudents was in the medium level scored 62.13 ± 12.54. The highest level was Uighur nursing students scored 67.76 ± 10.9, followed by other national nursing studentsscored 59.44 ± 12.99, the lowest level was Han national nursing studentsscored 56.41 ± 11.25 (F=69.654, P<0.05). The highest level of professional identity was secondary school studentsscored 66.71 ± 10.96, followed by junior college studentsscored 59.33 ± 8.23, the lowest level was undergraduate studentsscored 57.32 ± 12.54 (F=49.815, P < 0.05). Conclusions The professional identity of nursing students is not high,and were affected by many factors. It is suggested that nursing educational workers should take various measures to implement nursing students professional emotional education. Nursing teachers should possess higher level of professional identity,and guide students to set up the correct professional identity in various angles.

Objective To investigate the distribution of pathogens in elderly patients with bronchiectasis and drug resistance.Methods Elderly hospital patients with bronchiectasis were selected,pathogens isolated from sputum specimens and analysis of bacterial resistance.Results 221 strain of pathogen were isolated,of gram -positive bacte-ria 57 strain(25.79%),gram -negative bacteria 151 strain(68.32%);gram -negative bacteria Pseudomonas aerug-inosa pneumonia Klebsiella,Acinetobacter baumannii and Escherichia coli -based was 20.36%,14.02%,15.84%and 9.05% respectively;gram -negative bacteria Staphylococcus aureus,Staphylococcus epidermidis and Streptococ-cus pneumoniae based was 9.50%,8.60% and 7.69% respectively;other fungi,the proportion was 5.88%. Conclusion Elderly patients with bronchiectasis distribution of pathogens to the highest proportion of gram -negative bacteria,including Pseudomonas aeruginosa in the first row,tip rational use of antimicrobial drugs in reducing the rate of drug resistance plays an important role.

Objective To analyze the fetal growth ,development and birth situation in umbilical artery absent end‐diastolic flow(AEDF) in late pregnancy .Methods The umbilical artery blood flow signals were detected by color ultrasonic diagnostic in‐strument .The fetal growth indexes and Apgar score at birth were compared between the normal umbilical artery group and the AEDF group .Results The occurrence rate of fetal growth and development less than the gestational age was significantly higher than that in the normal group ,moreover the occurrence rate of intrauterine stress was also obviously higher than that of the normal group .Conclusion Umbilical arterial AEDF in late pregnancy prompts the fetal intrauterine hypoxia and relatively slowly fetal grow th .

After a description of the differences between formative evaluation and summative evaluation, the appli-cation of formative evaluation in literature retrieval course evaluation in medical colleges and universities was elabo-rated by analyzing the current situation of literature retrieval course and its evaluation in medical colleges and uni-versities with Xinjiang Medical University as an example, which showed that the principles should be followed when formative evaluation is applied in literature retrieval course evaluation.The problems related with the application of formative evaluation in literature retrieval course evaluation were pointed out.

For children suffering from primary nephrotic syndrome(PNS), podocyte is a crucial part of glomerular filtration barrier, whose injury usually causes proteinuria.The structural and functional integrity of podocyte cytoskeleton is the prerequisite of its normal physiological function.Recent studies demonstrated that under a certain pathological condition, B7-1, expressed in podocyte, can inhibit the activation of β1 integrin by competitively binding to the target site on the β1 integration, which may change the morphology and function of podocyte, consequently induced proteinuria.Other studies also have showed that abatacept, which selectively inhibit the cross-talk between B7-1 and β1-integrin,can reduce proteinuria in patients with B7-1-positive glomerular disease.These studies suggested that B7-1 may be a potential diagnostic biomarker and therapeutic target in proteinuria in PNS.This review summarizes the role of B7-1 expressed in podocyte in the pathogenesis of proteinuria and the possibility of clinical application in the future.

Glioma is a serious threat to human health.Increasing evidences indicate that abnormal expression and activities of a number of ion channels,e.g.voltage-gated K+,Ca2+,C1-channels,are involved in the growth,proliferation,migration and invasion of glioma cells.Ion channels may affect the occurrence and development of glioma cells through regulating the membrane potential,adjusting the cytoplasmic volume,ion concentration,and pH value.In-depth understanding the role of ion channels in formation,development and transfer process of glioma may provide new targets for glioma prevention and treatment.In this paper,the advanced studies of ion channels in glioma were briefly reviewed.

BACKGROUND:Ful-arch dental implant and sectional repair are mainly for patients with edentulous mandible, both of which have their own characteristics. Ful-arch dental implant restoration is suitable for the mandibular protection, but has unfavorable effects on the prosthesis; segmented restoration has better effects on the prosthesis. OBJECTIVE:To compare the clinical effectiveness of ful-arch dental implant and sectional repair in edentulous mandible patients as wel as patient satisfaction. METHODS: Forty patients with edentulous mandible underwent ful-arch dental implant restoration (n=28) or sectional repair (n=12). After restoration, al the patients were folowed for 1 year. Clinical examination and X-ray observations were performed to evaluate the osseointegration rate. RESULTS AND CONCLUSION:The success rate of implants was 100% in the ful-arch group and 98% in the sectional repair group, and there was no difference between the two groups (P > 0.05). The successful restoration rates were 96.5% and 98% in the two groups, respectively, with no significant difference (P > 0.05). Bone resorption showed no difference between the two groups at 3-4 months after implantation or at 12 months after restoration. Patients in the two groups were al satisfied with masticatory function, fixed effect, subjective comfort and pronunciation are satisfactory, and there was no statisticaly significant difference (P > 0.05). However, beautiful evaluation, maintenance convenience and total satisfaction were significantly higher in the ful-arch group than the sectional repair group (P < 0.05). These findings suggest that both ful-arch dental implant restoration and sectional repair can have better effects on edentulous mandible, but the former one is superior to the latter one in the folowing aspects: beautiful evaluation, maintenance convenience and total satisfaction.