1.Effects of Maca on kidney mitochondrial respiratory function and anti-aging capabilities in aged rats after exhausted exercise
Chinese Journal of Tissue Engineering Research 2016;20(18):2711-2716
BACKGROUND: Studies have shown that Maca can enhance immune cel function, improve mitochondrial respiratory chain enzymes, and play a role in anti-oxidation and anti-aging.
OBJECTIVE: To observe Maca effects on kidney mitochondrial respiratory function and anti-aging capabilities in elderly rats after exhausted exercise.
METHODS: 10-month-old elderly rats were intragastrical y administrated Maca powder 5 g/kg, once a day, and did treadmil exercise, 5 days in a week. Rats were randomly divided into control group, Maca group and training group and Maca+training group. At 6 weeks after training, rats in each group did exhausted exercise (35 m/min), and immediately received intraperitoneal injection of 2% sodium pentobarbital. The kidney was obtained, and mitochondria were extracted by differential centrifugation. A spectrophotometer was used to measure mitochondrial respiratory chain activity.
RESULTS AND CONCLUSION: (1) Mitochondrial respiratory chain enzyme and antioxidant enzyme activity: mitochondrial respiratory chain enzyme I-III, superoxide dismutase and glutathione peroxidase activities were higher in the Maca+training group than in the control group, Maca group and training group (P < 0.05 or P < 0.01), but malondialdehyde content was lower (P < 0.05 or P < 0.01). (2) Results suggested that the combination of supplement Maca and incremental exercise can improve mitochondrial respiratory function and delay aging in the kidney of aged rats after exhausted exercise. Moreover, supplemented Maca and incremental exercise have a synergistic effect.
2.Characteristics of medical and health literature novelty assessment in institutions of armed forces, its problems and solutions
Chinese Journal of Medical Library and Information Science 2014;(5):59-61
The characteristics of medical and health literature novel assessment in institutions of armed forces were described from the secrecy of projects for literature novelty assessment , the limitations of consignee institution , and the non-profitability of literature novelty assessment agency .The major problems of medical and health literature novel assessment in institutions of armed forces were elaborated in terms of the literacy, instability, competency and knowledge limitation of literature novel assessment staff with suggestions put forward for their solution such as strengthening the construction of talent team, joint development and sharing of resources.
3.Application of medical signal processing based on theory and method of chaos
International Journal of Biomedical Engineering 2006;0(02):-
Reviewing the theory of chaos in the field of nonlinear dynamics, this paper summarized theory of chaos and its applications in medical signal processing including electroencephalogram(EEG) signal?electrocardiogram(ECG) signal?electromyogram(EMG) signal, etc. The foreground is reviewed to advance the study and application of nonlinear dynamics theory in biomedical engineering.
4.Effects of vasopressin and adrenaline on cerebral resuscitation in rats undergone cardiopulmonary resuscitation
Chinese Journal of Emergency Medicine 2011;20(3):277-280
Objective To compare the effects of vasopressin and adrenaline on cerebral resuscitation in rats. Method Sixty male SD rats were used to set the animal model of cardiac arrest and were randomly (random number) divided into 4 groups (n = 15/group): sham operation group (sham-gro), negative control group (neg-gro), vasopressin group (vas-gro) and adrenaline group (adr-gro). Blood pressure was recorded, and brain tissue samples were obtained. Results There was no significant difference in the recovery rate between vas-gro and adr-gro 30 min after resuscitation (P <0.05). The mean blood pressure in vasgro was higher than that in adr-gro within 30 min (1,2, 5, 10, 20, 30 min) after restoration of spontaneous circulation. The measured MDA, SOD and GSH were significantly different (P < 0.05) between each two groups among vas-gro, sham-gro and adr-gro. Conclusions The recovery rate was similar between vasopressin group and adrenaline group during cardiopulmonary resuscitation in rats. However, vasopressin can to maintain the mean arterial pressure at a higher level after resuscitation, which can the increase the cerebral perfusion and reduce brain cell damage.
5.Effects of Hormone Replacement Therapy and Sport Walk with Weight on Serum Lipid and Bone Mineral Density in Postmenopausal Women
Chinese Journal of Rehabilitation Theory and Practice 2008;14(10):974-976
Objective To explore the effects of estrogen,sport walking with weight and estrogen plus sport walk on serum lipid,bone metabolism and bone mineral density(BMD) in postmenopausal women.Methods 52 postmenopausal women were divided into the hormone replacement therapy(HRT) group(n=12),sport walking with weight group(Sp group,n=14),HRT + Sp group(n=12) and control group(n=14).HRT group took compound nylestriol,Sp group took sport walking with 5 kg weight and exercise intensity was from 60% to 80% VO2max,HRT+Sp group received two treatments as HRT group and Sp group.The experimental duration consisted of six months.Results The total cholesterol(TC),TC/high density lipoprotein cholesterol(HDL-C),alkaline phosphatase(APL) and urine calcium(Ca)/creatinine(Cr) were markedly lower in three experimental groups than the control group and before experiment(P<0.05 or P<0.01),HDL-C in Sp and HRT+Sp groups were markedly higher than the control group and before experiment(P<0.05),BMD of spine(L2~L4) and left trochanter in three experimental groups were markedly higher than the control group(P<0.01) and before experiment(P<0.0).Conclusion Both estrogen replacement therapy and sport walking with weight effectively improve serum lipid,prevent and reverse osteoporosis induced by menopause in women.
6.Effects of SOD,NO,TNF-α and hs-CRP on atherosclerosis in patients with hypertension complicating diabetes mellitus
International Journal of Laboratory Medicine 2016;37(23):3285-3287
Objective To observe the effects of SOD ,NO ,TNF‐αand hs‐CRP on atherosclerosis in the patients with hyperten‐sion complicating diabetes mellitus (DM ) .Methods One hundred and thirty‐four inpatients in our hospital from January 2010 to January 2016 were selected ,including 45 cases of hypertension ,44 cases of type 2 diabetes Mellitus(T2DM ) and 45 cases of hyper‐tension complicating T2DM .IMT and serum SOD ,NO ,TNF‐α and hs‐CRP levels were detected .Contemporaneous 45 individuals undergoing healthy physical examination were selected as the healthy control group for conducting the contrastve analysis . Results The SOD and NO levels in the hypertension complicating T 2DM group were significantly lower thin the healthy control group ,hypertension group and T2DM group ,the difference had statistical significance (P<0 .05) .The levels of SOD ,NO ,TNF‐α, hs‐CRP and IMT had no statistical significance between the hypertension group and T 2DM group(P>0 .05) .IMT was positively correlated with TNF‐αand hs‐CRP(r=0 .636 ,0 .664 ,P< 0 .05)and negatively correlated with NO and SOD (r= -0 .586 ,0 .648 ,P<0 .05) .Conclusion Evaluating the change of SOD ,NO and TNF‐αand hs‐CRP levels can further investigate its occurrence mechanism and also has certain significance to the prevention and treatment of vascular injury chronic diseases such as hypertension and TM .
7.The Showbiz Art——Medical Science Living Character to Expand of New Carry A Body
Chinese Medical Ethics 1995;0(04):-
This text the showbiz art living character to expand to the medical science of help the function to carry on thorough analysis,thus further push forward the medical science living education for all-round development of smooth open an exhibition,exaltation medical science living of thought morals character,cultural character,mental state character with appreciate beauty ability,innovation ability,competence in interpersonal communication,for set up socialism harmony society development qualified medical science talented person.
8.Clinical Efficacy of Compound Glycyrrhizin Combined with Reduced Glutathione on Patients with Alcoholic Liver Cirrhosis
China Pharmacy 2007;0(35):-
OBJECTIVE:To observe the curative effects of compound glycyrrhizin used in combination with reduced glutahione for the treatment of alcoholic liver cirrhosis(ALC).METHODS:40 patients with ALC were randomized into the treatment group and control group.The treatment group was treated with compound glycyrrhizin 80mL and reduced glutathione 1.20g to observe the changes in hepatic function,hepatic fibrosis,clinical symptoms and therapeutic effects;whereas the control group was treated only with reduced glutathione 1.20g.The course of treatment lasted 2 weeks for both groups.RESULTS:After treatment for 2 weeks,the serum glutamic pyruvic transaminase(ALT),aspartate aminotransferase (AST),?-glutamyl transpeptidase(?-GT),total biliribin(TB),hyaluronic acid(HA),type Ⅲ procollagen(PC Ⅲ) and type Ⅳ collagen(Ⅳ-C) levels in the treatment group decreased markedly, the clinical symptoms were improved obviously,the total effective rates in the treatment group were 90% and there were significant differences in ALT, AST,?-GT,TB,HA,PC Ⅲ,Ⅳ-C levels.Cli-nical symptoms and total effective rates between treatment group and control group showed significant difference(P
9.Montmorillonite Powder vs.Racecadotril Granule for Acute Infantile Diarrhea:Cost-minimization Analysis
China Pharmacy 1991;0(05):-
0.05).The drug cost was(12.93?4.47)yuan vs.(33.62?4.87)yuan and the total medical cost was(43.2?9.72)yuan vs.(63.03?14.99)yuan,both showing no significant differences between 2 groups(P
10.On the Origin of Psychology Advisory Service and Its Development in China
Chinese Medical Ethics 1995;0(02):-
This article comprehensively analyzed the population able to provide psychology advisory service in China,including the common populace, and the specialized talents who are qualified to provide specialized psychology service.Various problems in the current psychology advisory service and their causing factors were elaborated,and based on which suggestions were proposed for a better application of psychology advisory service to the society.