Objective To compare the effects of vasopressin and adrenaline on cerebral resuscitation in rats. Method Sixty male SD rats were used to set the animal model of cardiac arrest and were randomly (random number) divided into 4 groups (n = 15/group): sham operation group (sham-gro), negative control group (neg-gro), vasopressin group (vas-gro) and adrenaline group (adr-gro). Blood pressure was recorded, and brain tissue samples were obtained. Results There was no significant difference in the recovery rate between vas-gro and adr-gro 30 min after resuscitation (P ＜0.05). The mean blood pressure in vasgro was higher than that in adr-gro within 30 min (1,2, 5, 10, 20, 30 min) after restoration of spontaneous circulation. The measured MDA, SOD and GSH were significantly different (P ＜ 0.05) between each two groups among vas-gro, sham-gro and adr-gro. Conclusions The recovery rate was similar between vasopressin group and adrenaline group during cardiopulmonary resuscitation in rats. However, vasopressin can to maintain the mean arterial pressure at a higher level after resuscitation, which can the increase the cerebral perfusion and reduce brain cell damage.

The characteristics of medical and health literature novel assessment in institutions of armed forces were described from the secrecy of projects for literature novelty assessment , the limitations of consignee institution , and the non-profitability of literature novelty assessment agency .The major problems of medical and health literature novel assessment in institutions of armed forces were elaborated in terms of the literacy, instability, competency and knowledge limitation of literature novel assessment staff with suggestions put forward for their solution such as strengthening the construction of talent team, joint development and sharing of resources.

BACKGROUND: Studies have shown that Maca can enhance immune cel function, improve mitochondrial respiratory chain enzymes, and play a role in anti-oxidation and anti-aging.
OBJECTIVE: To observe Maca effects on kidney mitochondrial respiratory function and anti-aging capabilities in elderly rats after exhausted exercise.
METHODS: 10-month-old elderly rats were intragastrical y administrated Maca powder 5 g/kg, once a day, and did treadmil exercise, 5 days in a week. Rats were randomly divided into control group, Maca group and training group and Maca+training group. At 6 weeks after training, rats in each group did exhausted exercise (35 m/min), and immediately received intraperitoneal injection of 2% sodium pentobarbital. The kidney was obtained, and mitochondria were extracted by differential centrifugation. A spectrophotometer was used to measure mitochondrial respiratory chain activity.
RESULTS AND CONCLUSION: (1) Mitochondrial respiratory chain enzyme and antioxidant enzyme activity: mitochondrial respiratory chain enzyme I-III, superoxide dismutase and glutathione peroxidase activities were higher in the Maca+training group than in the control group, Maca group and training group (P < 0.05 or P < 0.01), but malondialdehyde content was lower (P < 0.05 or P < 0.01). (2) Results suggested that the combination of supplement Maca and incremental exercise can improve mitochondrial respiratory function and delay aging in the kidney of aged rats after exhausted exercise. Moreover, supplemented Maca and incremental exercise have a synergistic effect.

Reviewing the theory of chaos in the field of nonlinear dynamics, this paper summarized theory of chaos and its applications in medical signal processing including electroencephalogram(EEG) signal?electrocardiogram(ECG) signal?electromyogram(EMG) signal, etc. The foreground is reviewed to advance the study and application of nonlinear dynamics theory in biomedical engineering.

Objective To explore the effects of estrogen,sport walking with weight and estrogen plus sport walk on serum lipid,bone metabolism and bone mineral density(BMD) in postmenopausal women.Methods 52 postmenopausal women were divided into the hormone replacement therapy(HRT) group(n=12),sport walking with weight group(Sp group,n=14),HRT + Sp group(n=12) and control group(n=14).HRT group took compound nylestriol,Sp group took sport walking with 5 kg weight and exercise intensity was from 60% to 80% VO2max,HRT+Sp group received two treatments as HRT group and Sp group.The experimental duration consisted of six months.Results The total cholesterol(TC),TC/high density lipoprotein cholesterol(HDL-C),alkaline phosphatase(APL) and urine calcium(Ca)/creatinine(Cr) were markedly lower in three experimental groups than the control group and before experiment(P<0.05 or P<0.01),HDL-C in Sp and HRT+Sp groups were markedly higher than the control group and before experiment(P<0.05),BMD of spine(L2～L4) and left trochanter in three experimental groups were markedly higher than the control group(P<0.01) and before experiment(P<0.0).Conclusion Both estrogen replacement therapy and sport walking with weight effectively improve serum lipid,prevent and reverse osteoporosis induced by menopause in women.

Objective To analyze the risk factors of bleeding after endoscopic resection of colorectal polyps.Methods 342 cases of colorectal polyps treated by endoscopic surgery in our hospital were taken as the research objects. The incidence of bleeding after endoscopic surgery was statistically studied. All the patients were divided into bleeding group and no hemorrhage group, with postoperative bleeding as the dependent variable, and related factors which may be induced postoperative bleeding (gender, age, diabetes mellitus, with hypertension and hyperlipidemia history, drinking history, polyp occurrence location, polyp pathology type, polyp size, morphology of colonic polyps, polyp number) as the independent variable to make advanced single factor regression analysis. Then using the logistic regression analysis tool for multivariate analysis.Results The incidence of postoperative bleeding was 7.60% (26/342) in 342 patients. Single factor analysis showed that the bleeding in the proportion of patients with hypertension was higher than that of without complication (P < 0.05), with history of high blood lipid ratio is higher than that of without complication (P < 0.05) and polyp diameter >2.0 percentage higher than that without complication (P < 0.05) and polyp morphology with pedunculated polyps proportion is higher than that without complication (P < 0.05). Multivariate analysis showed that the risk factors for bleeding after endoscopic resection of colorectal polyps were high blood pressure, high blood fat, polyp diameter >2.0 cm, and polyps were the risk factors of postoperative hemorrhage (P < 0.05).Conclusion The risk factors of bleeding after endoscopic resection of colorectal polyps, including hypertension, high blood fat, polyp diameter >2.0 cm, polyp morphology of pedicle polyps.

In the past decades, the advent of molecular targeted agents has been a considerable breakthrough for cancer patients, ex-cept for traditional operation, chemotherapy, and radiotherapy. As a novel therapeutic method, molecular targeting treatment is im-portant in the field of medical oncology, in which epidermal growth factor receptor inhibitors (EGFRIs) have been widely used as target-ed agents. Dermatological toxicities are the common side effects associated with the EGFRIs. Diarrhea, weakness, and pneumonia can be observed. EGFRI-induced dermatological toxicities may disrupt the health-related quality of life and cause anticancer treatment dose adjustments or discontinuance. The dermatological toxicities mainly involve rash acneiform, pruritus, xerosis, paronychia, hair change, and skin hypersensitivity. Treatment recommendations from guidelines include antibiotics, corticosteroids, and antihista-mines, but their clinical therapeutic efficacy have not been proven. Therefore, oncologists and dermatologists are investigating effec-tive medication. This article reviews the advances in the study of the clinical manifestations and drug therapies of EGFRI-induced der-matological toxicities to provide reference for clinical practitioners.

The construction of traditional theory of Chinese herbalism cannot do without the accumulated understanding of herb effect in clinical practice.Meanwhile,it closely relates to the natural history of using different theories of herb property to explain effect and mechanism at different stages.The compilation of Inner Canon of Yellow Emperor 《(黄帝内经》) and Shennong Bencao Jing 《神农本草经》) represent the initial formation of traditional herbalism in Chinese medicine.These two books have a relatively complete description of property and effects of herbs,but with different focus of concerning.After Shennong Bencao Jing,explaining the effect from property of herbs gradually become the developing trend and basic characteristics of herbalism.During the Ming-Qing Dynasties,publication of a large number of herbal annotation works further highlights this feature.

Optical coherence tomography (OCT) is a technology that imaging the ocular structure by the interference of light.OCT is invented and applied in the examine and measure of the retina and choroid.However,the development of spectrum domain make the study of ocular anterior segment structure possible.Anterior segment OCT (AS-OCT) can image the tissue structures of the cornea,anterior chamber,pupil,iris,etc.on the same picture.Also,AS-OCT can be used to measure the corneal surface and curvature after excimer laser in situ keratomileusis,the examination of the angle,iris,ciliary body in glaumatous eyes,the observation of dynamic alteration of the filtering bleb following antiglaucoma surgery and the evaluation of ocular anterior segment tissue after eye trauma.AS-OCT examined at a non-contact,non-invasive way with higher resolution and higher speed.In addition,AS-OCT offers the quantitative analysis of the ocular anterior segment.The clinical application,advantages and disadvantages,prospect of AS-OCT in ophthalmology were reviewed in this paper.

The project's scientific research project to improve the smooth knot problem for the credibility of Research management sector is very important,but in fact some of the project is not only the project node title,or because of subjective and objective factors that lead to project failure,brought credibility to the project undertaking unit loss.This common scientific research project on risk analysis and identification,reporting that the project's adverse reporting motivation,the strength of the research team,project costs capability,scientific research project of the natural properties of the risk,as well as technical and scientific research platform so may result in risk project delay or failure.Articles from Research management policies,systems,methods,attitude problem-a response.