This paper introduced the non-steroid anti inflammatory drugs in the treatment of arthropathy including classification, mechanism of action, principles of using, major drugs, indication, contraindication, effects and side effects, drug- drug interaction, dosage and administration, how to reduced and manage the side effects in the gastrointestinal tract.
Anti-Inflammatory Agents, Non-Steroidal ; Arthropathy, Neurogenic ; therapeutics

Clnical and endoscopic manifestations of gastro-duodenal injuries in 178 patients caused by nonsteroidal anti-inflammatory drugs (NSAID) were compared with these of 84 patients without treatment of NSAID. We concluded that abnomal rate in gastro-duodenal endoscopy is 86.0 % in the group treated by NSAID. Gastric injury rate is 80.9 %, including 22.5% of gastric ulcer (p<0.01). Duodenal injury rate is 29.2 %. including 22.5% of duodenal ulcer (p<0.01). Clinical features: epigastric pain rate is 42.7%; abdominal distention is 11.8%. These symploms are useful in predicting gastrointestinal injuries. These lesions more likely severe if the patient have following factors: above 60 years old; alcoholism, smosking, using NSAIDs for long time, using high dose of the NSAIDs. There is not relation between endoscopic manifestations, type of rheumatic disease and HP infections.
Anti-Inflammatory Agents, Peptic Ulcer

Authors introduced some classes of drugs for treating rheumatic arthritis. Basic drug group includes biological agents, anti TNF drugs such as Entanercept- Enbrel; Infliximab; Adalimumab- Humira. In non-steroidal anti-inflammatory drugs (NSAIDs) group, there are Meloxixam - Mobic; Nimesulide- B- Nalgesine; Nise, Celecoxib- Celebrex; Rofecoxib- Vioxx; Valdecoxib-Bextra; Parecoxib- Dynastat; Etoricoxib-arcoxia. Group of slow released antirheumatic drugs included diacetylrÐine or diacerhÐine (ART 50). A new therapy that gave rapid and long lasting pain relieve, more viscosity of articular fluid is administration of sodium hyaluronate (Hyalgan, Ostenil, Hyruan) intra-articular injection
Antirheumatic Agents ; Drugs, Investigational ; Pharmaceutical Preparations

The joint degeneration can occur in all people in the world. The rate of joint degeneration in men was the same as this in women. However, the rate of knee joint degeneration in women was higher than this in men while the rate of hip joint degeneration in men was higher than this in women. The principles of the treatment comprised the reduction of process of joint damage, especially prevention of the articulate cartilage degeneration and pain relief, maintenance of the moving ability and minimization of the handicap
Knee ; Knee Injuries ; Joints

42 patients with gonarthritis were diagnosed according to ARA standard at Bachmai Hospital. Gonarthritis is commonly seen in females age over 50 with 85,7%. Favorable factors of disease are working hard jobs with 64.3%, menopausal age is 80,6% and women had 3 children or over. Features of clinical and X-ray symptoms were not different previous studies.
Clinical Trial [Publication Type] ; X-Rays

A study on 125 patients, who were operated on lumbar spinal disk herniation, included 67 men and 58 women, from 18-70 years old. These patients were divided into 2 groups: group 1 was given epidural anesthesia: 34 men and 32 women used bupivacaine 1mg/kg –1, fentanyl 1µg/kg-1, adrenaline 1/2000.000 with a volume of desensitizer was 1.5 – 1.6ml/spinal cord unit. Fentanyl was mixed into drug injected in extra dura mater. Group 2 was given subarachnoid anesthesia: 33 men and 26 women used bupivacaine 0.15mg/kg –1, fentanyl 1µg/kg-1. Respiration indexes had been measured before and after anesthesia 30 minutes. Results: 30 minutes after anesthesia, group 2 had a decrease of the respiration indexes such as VC, VC%, FEV1, and Tiffeneau, compared that before anesthesia (p<0.05). In the group 1, the respiration indexes reduced not significantly with p> 0.05. Subarachnoid anesthesia had Tiffeneau and VC% were lower than epidural anesthesia (p<0.05). The respiration indexes of subarachnoid anesthesia group decreased but still in the allowance limitation.
Respiration ; Hernia ; Anesthesia ; Surgery

From June 1993 to October 2001, in Central Institute of Pediatrics and Viet Duc Hospital, 13 cases of plastic surgery were performed to restore the clitoris and vagina. Among them, 12 female patients with virilisant adrenogenital syndrome had had indication of clitoris restoration surgery, 1 patient with true hermaphrodism. The restored clitoris accessed proper size with normal development and sensation
Surgery, Plastic ; Mucous Membrane ; Vagina ; Penis

We have investigated the correlation between blood glucose level and Glasgow coma score (GCS) in 35 patients with acute phase of stroke (mean age: 64 with a mean evolution period of 29 hours after stroke onset). Blood glucose level on admission (Gn)11.1mmol/l in 20%, fasting glucose (GO)  7mmol/l in 51.4% and 2-hour postload glucose (G2) 11.1 mmol/l in 57.1% of the patients. Group 1 (normo-glycemia) accounted for 28.6%; group 2 (hyperglycemia and HbA1c<6% Hb), 40% and group 3 (hyperglycemia and HbA1c<6% Hb), 31.4% of the patients. In group 1,2 and 3, GCS was  11 in 70%, 92.8% and 100% respectively. GCS also correlated with Gn (r=0.457), G0 (r=-0.468) and G2 (r=-0.349). There was a significant difference between group 2 and group 3 on Gn (8.42+/-2.34mmol/l vs 9.75+/-4.10 mmol/l, p<0.05), G2 (11.67 mmol/l+/- 2.26 mmol/l vs 15.33 mmol/l +/- 5.43 mmol/l, p<0.01) and HbA1c (5.45+/-0.6% Hb vs 6.75+/- 0.73% Hb, p<0.005). During acute phase of stroke, especially in brain heamorrage, hyperglycemia frequently takes place, in correlation with Glasgow coma score, hyperglycemia is, therefore, considered as one of the predictors of severity in acute phase of stroke.
Hyperglycemia ; Blood Glucose ; Cerebrovascular Accident

During 1997-1999, 19 pediatric patients with ages of 3-5 (10 cases) and ages of 6-11 (9 cases) and hypospadias in the institute of pediatric operated as mustarded technique the results have shown that early complications (4) were conservative treated well. The follow up duration of 1-16 months showed good outcome.
Hypospadias ; Complications ; Surgery

Transurethral electrovaporisation of prostate (TVP or TUVP) is a new modification of transurethral resection of prostate (TURP). The goal of TVP in benign prostatic hyperplasia (BHP) is reduce the incidence of TURP complications. From 1996 to June 1997, the first time 12 patients have been indicated TVP for BHP in Cho Ray Hospital. The participants included those who have been not operated and those who have been operated using TURP previously. Several kinds of electrodes were used. The roller type was better but it makes the time of TVP longer. The sharp type is easier to cause complications. Perforation of capsule occurred in one patient.
Prostatic Hyperplasia ; therapy