Objective To investigate the therapy-related complications of circulation of antithymocyte globulin on severe aplastic anemia.Methods Clinical data of 39 patiants with severe aplastic anemia who received ATG treatment from April 2005 to April 2008 were analyzed.Results Clinical evidence of complications of circulation developed in 34 patients,especially in the first day.Conclusion Therapy-related complications of circulation occured in most of the patients.It was necessary to pay attention to monitoring the circulation when we use antithymocyte globulin.

Herbal Paste is one formulation come down from antient China,which is essence of traditional medicine. Herbal Paste has the following characteristics:First, it pays great attention to comprehensively, overall recuperation;Second,it attaches importance to Syndrome Identifation and Constitution of traditional medicine; Third, it can adjust physique and has wide application.Fourth, it has moderate effect and it is stable and lasting.The application of Herbal Paste in ‘Prevention Diseases’ can provide positive guidance for the diagnosis and treatment of many clinical diseases.

Wir untersuchten die kapillare Dichtigkeit an 6 Aeren der Grosshirnrinde.Die Materialien bestanden aus 6 Gehirnen von Kindern im Alter von 1—2 und 5 Jahren und 2 Gehirnen von Hunden. Diesen 8 Gehirnen injezierten wir Gelatinetusche,bzw.25% Argyrol. 1 Die Kapillaren der Grosshirnrinde und des -markes bildeten zusammen ein dichtes,mitein- ander verbundenes Netz.Die Netzmaschen in der Grosshirnrinde waren enger als diejenigen des Grosshirnmarkes. 2 Die kapillare Dichtigkeit in der Grosshirnrinde war groesser als jene des Markes.Die dur- chschnittliche kapillare Laenge von 6 Grosshirnrindschichten war 3,26:1 im Verhaeltnis zu der Laenge des Grosshirnmarkes.Die an Gefaessmenge mangelnde 1.Schicht besass eine kapillare Laenge,zweimal groesser als die des Markes. 3.Die kapillare Dichtigkeit zwischen 6 Schichten der Grosshirnrinde war ganz verschieden; die 4.Schicht war am staerksten,die 1.Schicht am schwaechsten. 4.Die Blutgefaessverteilung in den 6 Aeren der Grosshirnrinde war im motorischen Rinden- feld am reichsten;im sensiblen Rindenfeld,Schzenrum,Hoerzentrum,frontalem Pole und Riechzen- trum nahm sie stufenweise ab.Dies bedeutet,dass die Blutversorgung des Paloccortex am aermsten war.Dort wo die Nerventaetigkeit am kompliziertesten war,waren die Blutgefaess verteilung relativ reicher.

OBJECTIVE To review the alteration of distribution of familiar Gram-negative bacteria of lower respiratory tract infection for patients in intensive care unit(ICU) of our hospital for reference to rational administration of clinical antibacterial drug.METHODS The 476 strains out of 736 strains collected from patients of our hospital during Jan 2003 to Dec 2006 were Gram-negative bacteria,positive ratio was 64.67%,and the features of distribution and alteration were statistically summarized.RESULTS The main germs of the 476 strains were Acinetobacter baumannii(102 strains),Pseudomonas aeruginosa(94 strains),Klebsiella pneumoniae(66 strains),Escherichia coli(54 strains),and Stenotrophomonas maltophilia(33 strains).CONCLUSIONS The main germs of pathogenic germs of lower respiratory tract infection for patients in ICU are Gram-negative bacteria,among which the isolation ratio of A.baumannii is the highest.But S.maltophilia is increasing gradually,indicating that clinical doctor should watch alteration of Gram-negative bacteria,and rationally use antibacterial drug in order to raise cure rate.

Objective:To investigate the effect of Dan Sen on gastric mucosal Na +-K +-ATPase activity and gastric transmucosal potential difference in rats during severe intraperitoneal infection.Methods:The intraperitoneally infected rat model was established by cecal ligation and puncture(CLP).Assay of Na +-K +-ATPase activity in gastric mucosal tissue was conducted by biochemistry method.The electric-physiological recorder meter was used to measure gastric mucosal potential difference.Results:The activity of Na +-K +-ATPase markedly decreased in infected group at 3h after perforation,compared with the control group ( P

Objective:To know the thermal and vibratory thresholds in normal subjects and their relation with age,sex,site and methods.Methods:We used TSA-2001 Ther mal Sensory Analyzer and VSA-6003 Vibratory Sensory Analyzer.Thermal and vibratory tests were performed in 100 healthy subjects on four sites with two methods(reaction time inclusive method and reaction time exclusive method).Results:The normative data of thermal and vibratory thresholds were presented in the table 2 to table 4 in the paper.There were no significant differences in TT and VT between men and females.TT and VT increased with age.There was difference in different sites.TT and VT obtained by the method of limits were higher than those obtained by the method of levels or staircases and it showed a significant positive correlation with each other.Repeatability of the QST allowed for longitudinal studies.Conclusion:QST may assess the sensory functions of human body quantitatively,and the TT and VT are influenced by testing method,site and age of subjects.

Objective To study the expression of connexin 43 in human cardiac conduction system(CCS) and heart. Methods The distribution of CX43 was studied immunohistochemically using of SABC method with antibody CX43. Results Smaller amounts of CX43 can be seen in the nodal myocytes at the periphery of sinoaterial and atrioventricular node whereas in the myocytes at the center of nodes were negative. In the Purkinje fibers, abundant expression of CX43 was found, and in atrial and ventricular myocardium contained abundant amounts of CX43, especially in the intercatalated disk.Conclusion The expression of connexin 43 varies greatly in specific regions of the human heart with different conduction properties. These differences may play a role in regulating electric impulse of cardiac conduction.

Objective:To evaluate the understanding and success rate in diagnosis and treatment of adrenal cortical tumor in children.Methods:6 cases were analyzed retrospectively about diagnosis,treatment,pathomorphological changes and prognosis.Results:6 cases of adrenal cortical tumor were treated surgically,which include 4 of cases Cushings syndrome,4 cases developed HBP,in 1 case developed hyperglycemia and in another case had hypokalemia developed.1 patient died of Ⅲ AVB(atrial ventricle block,AVB) during operation.Conclusion:Early diagnosis and early surgical interventions are crucial for treatment.Perioperative management plays an important role in improving prognosis.

AIM: To establish the quality standard of Wumeirendan (Fructus Mume, Radix et Rhizoma Glycyrrhizae, Mentholm, etc.) METHODS: Fructus Mume was identified by TLC. Menthol was determined by GC, Ammonium glycyrrhiziate was determined by HPLC. RESULTS: The average recoveries were 103.5% and 100.3%, RSD were 0.76% and 1.03%. The TLC sports developed were fairly clear, and the blank test showed no interference. CONCLUSION:The method developed is simple and accurate with good reproducibility, and the method can be used for quality control of Wumeirendan.

Objective: To understand the effect of different rates of stimulus on thermal threshold.Methods: TSA-2001 Thermal Sensory Analyzer was used.The cool,warm,cold pain and heat pain thresholds were determined at the two body sites in two group of age-matched health adults at different rates of stimulus by the method of "Limits".Results: There was no significant difference between the cool threshold and warm threshold at two sites.There was smaller cool pain threshold on left dorsum pedis and heat pain threshold on left fingers as the rate of stimulus was faster,while larger thresholds appeared as the temperature change was slower.There was significant difference between the above-mentioned two thresholds at different rates of stimulus.There was no significant difference between the thresholds of the cold pain on left fingers,the heat pain on left dorsum pedis.Conclusion: There is no significant difference between the warm,cool thresholds at the different rates of thermal stimulus by the method of "Limits" when the rate of thermal stimulus is low and the difference of two rates of thermal stimulus is smaller.The cool pain and heat pain threshold may degrade or not differentiate when the increase of the rate of stimulus is not enough.