1.Clinical observation of hemabate combined with uterine massage in treatment of postnatal hemorrhage caused by uterine inertia
Chinese Journal of Primary Medicine and Pharmacy 2011;18(4):478-479
ObjectiveTo explore clinical effect of hemabate combined with uterine massage in treatment of postnatal hemorrhage caused by uterine inertia. Methods120 patients with postpartum hemorrhage caused by uterine inertia were selected and randomly divided into the experimental group(60 cases)and the control group(60 cases).The experimental group was given hemabate combined with uterine massage treatment,with respect to only hemabate treatment in the control group. ResultsThe total effective rate of postpartum hemorrhage were 96.7 and 92% with significant difference(x2 = 15.396,P<0.01)between the two groups. Conclusionhe treatment of hemabate combined with uterine massage was more effective than hemabate alone.It was particularly safe,effective,convenient to operate,quickly to get results and of great value for clinical promotion.
2.Analysis on Privacy Issues of Computer and Internet
Journal of Medical Informatics 2009;30(8):31-33
Computer and Internet become a great threat to personal privacy. The paper introduces several forms of how computer and Internet threaten personal privacy, such as drive-by installation, webbug, electronic payment mechanism, as well as other computer or network application with potential privacy destruction, and provides some policies for protecting privacy, including improving legal system, applying websites privacy seal, etc.
3.Autophagy and nervous system disease
International Journal of Pediatrics 2010;37(6):610-612
Autophagy is an intracellular degradation system that delivers cytoplasmic constituents to the lysosome and it's involved in the cycle of matter and energy. Meanwhile autophagic cell death is a form of cell death called type-Ⅱ programmed cell death. In recent years, studies have shown that autophagy is involved in pathophysiologies of nervous system disease especially neurodegenerative diseases, ischemia-hypoxia, traumatic brain injury ,seizures.
4.Research progress on tumor suppressor gene PTEN in gastric carcinoma
Cancer Research and Clinic 2012;24(7):495-497
PTEN is a tumor suppressor with double specific phosphatase activity,and PTEN brings into its lipid and protein phosphatase activity through PIP3, FAK, MAPK pathway. PTEN also induces apoptosis, inhibits cell growth, and regulates cell migration and adhesiveness. PTEN expression is lower in gastric carcinoma. It may be valuable to evaluate that the abnormal expression of suppressor gene PTEN participates in the malignant conversion process of the gastric mucosa cell, and the expression levels of the PTEN protein can be used to evaluate the pathologic biology behavior of gastric carcinoma.
5.The value of cardiovascular magnetic resonance for diagnosis of viral myocarditis
International Journal of Pediatrics 2012;(6):624-627
Endocardial myocardial biopsy is the gold standard in the diagnosis of viral myocarditis.However,the limitations of sampling to the low sensitivity,and invasive inspection methods limit its clinical application.The traditional diagnostic tool electrocardiography,laboratory values and echocardiography are lack of specificity.Thus,a non-invasive diagnostic approach with high sensitivity is in need.Cardiovascular magnetic resonance(CMR) can evaluate the function of the heart parameters,such as left ventricular function and regional wall motion,and various CMR imagings including T2-weighted imaging,and early- and late-contrast enhanced T1-weighted imaging can evaluate the hyperemia,oedema and necrosis of myocardial inflammation histological character.CMR provides a scientific basis for the diagnosis of viral myocarditis in clinical.
6.Analyses enteral nutrition some problems in children
International Journal of Pediatrics 2013;(1):102-103
Enteral nutrition therapy is the first choice of clinical nutrition therapy method in children with disease.We should make full use of the gastrointestinal function and total nutritional therapy.The key is based on gastrointestinal function choose enteral nutrition infusion way,infusion pattern and prevention and treatment of refeeding syndrome.As following is introduction about a few problems.
7.The risk factors analysis and prevention of recurrent laryngeal nerve injury during thyroid operation
Chinese Journal of Postgraduates of Medicine 2013;(8):25-27
Objective To investigate the risk factors and prevention of recurrent laryngeal nerve injury during thyroid operation.Methods The clinical data of 2180 patients with thyroid operation were retrospectively analyzed.The potential relationship of the incidence rate of recurrent laryngeal nerve injury were evaluated,such as age,gender,nature of lesions,thyroid pathology,anesthesiology,operation times,whether or not to reveal recurrent laryngeal nerve.Results The overall incidence rate of recurrent laryngeal nerve injury postoperatively was 2.7% (59/2180).The incidence rate of recurrent laryngeal nerve injury in patients with thyroid malignant neoplasms,repeated surgery and without reveal recurrent laryngeal nerve were 6.7% (33/492),5.6% (15/267),4.4% (39/891),significantly higher than those in the patients with thyroid benign neoplasms,first time operation and with reveal recurrent laryngeal nerve [1.5% (26/1688),2.3% (44/1913),1.6% (20/1289)] (P < 0.01).In the patients with thyroid dorsal lesion,the incidence rate of recurrent laryngeal nerve injury in the patients without reveal recurrent laryngeal nerve was significantly higher than that in the patients with reveal recurrent laryngeal nerve[13.7%(29/212) vs.2.9%(12/417),P<0.01].Conclusion Thyroid malignant neoplasms,repeated surgery and without reveal recurrent laryngeal nerve can increase the risk of recurrent laryngeal nerve injury,routine reveal recurrent laryngeal nerve in the patients with thyroid dorsal lesion can decrease the incidence rate of recurrent laryngeal nerve injury.
8.Observation On the Curative Effect of Tangshentongbao Decoction Combined Benazepril on 31Cases of Diabetic Nephropathy in Clinical Stage
International Journal of Traditional Chinese Medicine 2009;31(2):136-137
Objective To assess the protective effect of Tangshentongbao decoction combined benazepril on renal function of the patients with diabetic nephropathy(DN) in clinical stage and to make a effective contrast to the therapy with western medicine. Methods 62 patients with DN in clinical stage were randomly divided into a control group and a treatment group, with 31 patients in each group. Both groups were supplied with the same food, adopted glucose control therapy and symptoms orientated treatment. On these basis, the treatment group was administered with Tangshentongbao decoction combined benazepril, and the control group was taken kallikrein enteric tablet combined benazepril. The therapeutic courses for both groups were 8 months. The changes of symptoms and physical signs, 24-hour urinay protein (24hUpro), serum cteatimine (SCr), serum creatinine clearance erate (CCr) , blood urea nitrogen (BUN), triglyceride (TG), cholesterd (CHO) and low density lipoprotein-cholesterol (LDL-C)of the two groups were separately assessed. Results 24hUpro, SCr, TG, CHO and LDL-C of treated group were all reduced after the treatment (P<0.01 or P <0.05), showing significant difference compared with the control group. Conclusion 24hUpro and SCr of patients with DN in clinical stage can be evidently reduced by Tangshentongbao decoction, and the effect of reducing blood lipid is remarkable better than western medicine alone.
9.Study on intervention of impaired glucose tolerance patients in community with Chinese medicine
International Journal of Traditional Chinese Medicine 2012;34(10):879-881
ObjectiveTo observe the turnover of impaired glucose tolerance(IGT)patients intervened with different measures.MethodsIGT 158 patients found by physical examination in the community residents were randomly divided into health education group,Chinese medicine group,and western medicine group,and treated with health education,traditional Chinese medicine and western medicine respectively.The fasting blood glucose,oral glucose after 2hour blood glucose (2hPG),serum lipid,glycosylated hemoglobin index were observed.ResultsThe efficiency of patients with IGT was 48.0%,70.3% and 75.0% in health education group,Chinese medicine and western medicine respectively.There was significant difference of therapeutic effect between the western medicine group and health education group (x2=7.96,P<0.05),and between the traditional Chinese medicine group and health education group (x2=5.46,P<0.05),while there was no significant difference between the traditional Chinese medicine group and Western medicine group (x2 =2.31,P>0.05).ConclusionTraditional Chinese medicine and Western Medicine both have good effects on patients with IGT.But due to its good tolerability and few side effect,TCM may be more easily accepted by patients.
10.A clinical controlled study on schizophrenia treated with paliperidone-ER and risperidone
Chinese Journal of Primary Medicine and Pharmacy 2011;18(17):2339-2340
Objective To compare the efficacy and side effects of paliperidone-ER and risperidone in treating schizophrenia.Methods 60 patients of schizophrenia were treated with paliperidone-ER( n = 30) or risperidone (n =30) randomly,for 8 weeks. The efficacy was assessed with the positive and negative symptoms scale( PANSS), and the safety was assessed with treatment emergent symptoms scale before treatment and at the ends of week 1,2,4and 8 treatments,respectively. Results The PANSS scores of two groups were significantly decreased after the patients received the drug treatment. Paliperidone-ER group showed lower negative symptom score at week 4 and 8 than risperidone group. The efficacy of study group was significantly higher than that of control group. Conclusion Paliperidone-ER was effective and safe antipsychotic drug with significant improvement compared with risperidone in negative symptoms.