No abstract available.

No abstract available.
Syringoma

OBJECTIVE: The purpose of this present study was to compare mouse embryo development in 3 commercial media and hatching competence of mouse embryo with or without enzymatic treatment. METHODS: Collected 375 mouse embryos were divided into three groups, and then cultured in IVF-20 (G2), Medicult IVF (M3), P-1 (blastocyst M), respectively. Three day mouse morulae were cultured in G2 media treated with pronase. The results were analyzed using Chi-square test, and considered statistically significant when p<0.01. RESULTS: The developmental rate of 2 cell mouse embryo after 72 hours was highest in IVF-20 (G2) among conventional 3 media. The hatching rate of mouse morulae was low when clultured in G2 media without pronase during 48 hours. However, it was higher when cultured in media treated with l mg/ml, 2.5 mg/ml, 5 mg/ml pronase, respectively. CONCLUSIONS: Using good media and digestion of zona pellucida with enzymatic treatment improve development and hatching rate of embryo. Therefore, implantation and pregnancy rate could be improved.
Animals ; Digestion ; Embryonic Development ; Embryonic Structures* ; Female ; Mental Competency ; Mice* ; Morula ; Pregnancy ; Pregnancy Rate ; Pronase* ; Zona Pellucida

No abstract available.
Pregnancy* ; Pyelonephritis*

No abstract available.
Pulmonary Atelectasis*

PURPOSE: We designed this study to identify and suggest the reasonable timing of adjuvant radiotherapy in the treatment of uterine carcinosarcoma according to the surgical intent and patterns of progression. MATERIALS AND METHODS: We retrospectively analyzed a total of 50 carcinosarcoma patients diagnosed between 1995 and 2010. Among these 50 patients, 32 underwent curative surgery and 13 underwent maximal tumor debulking surgery. The remaining five patients underwent biopsy only. Twenty-six patients received chemotherapy, and 15 patients received adjuvant radiotherapy. RESULTS: The median follow-up period was 17.3 months. Curative resection (p < 0.001) and stage (p < 0.001) were statistically significant factors affecting survival. During follow-up, 30 patients showed progression. Among these, eight patients (16.0%) had loco-regional progression only. The patients who had received adjuvant radiotherapy did not show loco-regional progression, and radiotherapy was a significant negative risk factor for loco-regional progression (p = 0.01). The time to loco-regional progression was much earlier for non-curative than curative resection (range, 0.7 to 7.6 months vs. 7.5 to 39.0 months). CONCLUSION: Adjuvant radiotherapy in the treatment of carcinosarcoma might be related to a low loco-regional progression rate. Radiotherapy should be considered in non-curatively resected patients as soon as possible.
Biopsy ; Carcinosarcoma ; Follow-Up Studies ; Humans ; Radiotherapy, Adjuvant ; Retrospective Studies ; Risk Factors

OBJECTIVES: The aim of this study was to review 10 years' experience of cesarean hysterectomy at our hospital. METHODS: A retrospective study of 37 cases of cesarean hysterectomy between Jan, 1, 1989, and Dec, 31, 1998 was carried out and then method of delivery, maternal age, parity, indication for hysterectomy, amount of transfusion, factors associated with adhesive placenta, and complications of hysterectomy were analysed. RESULTS: The incidence of cesarean hysterectomy was 1 in 639 deliveries. Overall, 0.55% of cesarean sections and 0.02% of vaginal deliveries were followed by cesarean hysterectomy. The higher the age and the parity of patients, the higher incidence of cesarean hysterectomy(p=.000, respectively). The most common indication of cesarean hysterectomy was adhesive placenta(54%). Placenta previa and two more prior cesarean delivery were main risk factors for development of adhesive placenta (Odds ratio: 9.6, 6.1, respectively ; 95% Confidence interval: 2.1-43.5, 1.1-34.2, respectively). Although no maternal deaths occurred, maternal morbidity remained high, including need for transfusion in 29 patients(78%) intraoperative urologic injury in 10 patients(27%), and pulmonary congestion or edema in 7 patients(19%). CONCLUSION: As the incidence of cesarean section and its association with placenta previa and/or accreta continue to rise, we may encounter Cesarean hysterectomy with increasing frequency. Still, cesarean hystere ctomy remains a potentially life saving procedure with which every obstetrician must be familiar.
Adhesives ; Cesarean Section ; Edema ; Estrogens, Conjugated (USP) ; Female ; Humans ; Hysterectomy* ; Incidence ; Maternal Age ; Maternal Death ; Parity ; Placenta ; Placenta Previa ; Pregnancy ; Retrospective Studies ; Risk Factors

PURPOSE: Magnetization transfer imaging(MTI) is a new imaging contrast technique. Our MT pulse sequence is designed as fixed time interval between echo and MT pulse. This study was peformed to evaluate the influence of variations in TR/TE on MTR in T1 weighted image of normal brain tissue on this kind of MT pulse sequence. MATERIALS AND METHODS: Seven healthy volunteers in twenties of age as the objectives, MRI was taken under various TR/TE(TR/TE ;700/14, 650/14, 750/14, 700/20 and 1500/20 msec). MTR was calculated from signal intensities measured at the same point in both pre and post MT images and statisticslly analyzed. The MR imager used in this study was 1.0T Magnetom 42SP(Siemens, Erlangen, Germany) and the parameters of additional MT pulse sequence were offset 1000Hz and bandwidth 250Hz, and posteriorly located to echo with 7.7 msec fixed interval. Offset of this MT pulse was variable. RESULT: In white matter of brain tissue from a normal person, MTR was 34-39%(average 37%) for TR and TE of 700/14 in T1WI and 33-36%(average 35%) for TR/TE of 650/14, and 34-38%(average 35%) for TR/TE of 750/14 which showed no statistical difference. However, in case of 1500/20 of TR/TE, MTR was 26-28%(average 26%) which is statistically significant. With TR/TE of 700/14 as the standrd value, the MTR of gray and white matter were 37% and 29% respectively, showing a definite difference of statistical means. Signal from CSF in ventricles is rarely influenced by MT pulse. CONCLUSION: Conclusively, a subtle variation in TR/TE in T1WI has little influence on MTR but wide range of variation in TR/TE as in proton density image induces significant difference in MTR on this kind of MT pulse sequence. Therefore, the exchangeable usage of MTR data would be possible in narrow range of TR/TE change but difficult in wide range of variation.
Brain* ; Healthy Volunteers ; Humans ; Magnetic Resonance Imaging ; Protons ; Reference Values*

No abstract available.
Histamine* ; Pruritus*

Neurodegenerative disorders cause a variety of dementia including Alzheimer disease, frontotemporal dementia, dementia with Lewy bodies, corticobasal degeneration, progressive supranuclear palsy, and Huntington's disease. PET scan is useful for early detection and differential diagnosis of these dementing disorders. Also, it provides valuable information about clinico-anatomical correlation, allowing better understanding of function of brain. Here we discuss recent achievements PET studies regarding these dementing disorders. Future progress in PET technology, new tracers, and image analysis will play an important role in further clarifying the disease pathophysiology and brain functions.
Alzheimer Disease* ; Brain ; Dementia* ; Diagnosis, Differential ; Frontotemporal Dementia ; Huntington Disease ; Lewy Bodies ; Neurodegenerative Diseases ; Positron-Emission Tomography ; Supranuclear Palsy, Progressive