1.Investigate some heavy metals concentration: lead, cadmium, arsenic and mercury at fresh water fish and snail in Hanoi markets
Journal of Vietnamese Medicine 2003;288(9):85-91
By atomic absorbance spectrophotometry, the content of heavy metals (lead, cadmium, arsenic, mercure) in freshwater fish and shelfish in the market and in 2 lakes in Hanoi from June to December 2002 was analysed. The contents are: lead 100%, arsenic 98.5%, cadmium 92.9% and mercury 88.6%, they are in the tolerable limits according to 1998 year Vietnam MOH regulation 867/BYT. The contents of various heavy metals are not similar in diverse genera of fish and shelfish. In some genera of fish, arsenic contents are higher than average from 0..68 to 0.601 mg/kg and mercury content 0.053mg/kg. Heavy metal contents in 2 lakes of Thanh Tri district and in diverse markets in Hanoi have not significant differences
Metals, Heavy
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Mercury
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Lead
2.Study on dosage of theophylline in saliva by HPLC method
Pharmaceutical Journal 1999;282(10):24-25
Theophylline is one of drugs, which have the confined concentration of treatment (10-20mcrg/ml). Uptake, release depend significantly on individuals, thus the control of concentration is the obligatory affair to guarantee effective and safe. Many studies have been demonstrated that the concentration of theophylline in saliva and plasma have been had closely interrelated rate and quite stable. This rate about 0.5-0.6. Therefore, the suggestion use of concentration of theophylline in saliva to evaluate on comparing bioavalbility of manufactured products, which is necessary affair with high practicability
Theophylline
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Saliva
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Chromatography, High Pressure Liquid
3.Synthesis of some thiazole derivatives with anti fungal and anti microbial potential
Pharmaceutical Journal 1999;282(10):12-15
The synthesis, structure elucidation and bio-activity of certain new 2-subtituted thiazole derivatives were reported. The newly prepared compounds were screened for their in vitro antibacterial and antifungal activities. The result revealed that almost compounds were active against fungi, 5 compounds were active against gram-positive bacteria. Meanwhile, 3 compounds had a remarkable both antibacterial and antifungal activities.
Thiazoles
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Analogs & derivatives
4.Synthesis and investigation and antifungal and antibacterial properties of some 2-amino thiazole derivatives
Pharmaceutical Journal 1999;282(10):13-15
Condensing 2-amino-4-methyl-5-carbe thoxythiazole obtained from the cyclization process between thioure and ethylacetoacetate and oidine with some acylating agents to yield 9 new compounds of thiazole. All of them were screened for their invitro antibacterial and antifungal activities with respect to clotrimazol and cloramphenicol. The results showed that [2-(3,5-substuted salicylamido)-4-methyl-5-car-bethoxythiazole] compounds are active against gram-positive bacteria.
2-aminothiazole
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Analogs & derivatives
5.Assessing the actuality of oral diseases of Yen Bai National primary pupils
Journal of Medical Research 2001;16(3):35-39
The oral community survey in Yen Bai was conducted in 1997. 804 pupils (girls and boys aged 6 to 11 years old) who were ethnic minority primary pupils were examined for Dental caries and periodontal status and some of concerned elements using standard 1988 WHO basis oral health. Survey method and test question. Percentage of pupil affected by Dental carries of milk teeth: 41.79%, highest in Kinh group, lowest in Tay group. It is not alien from delta area and highland. Periodontal status: percentage of pupils who had CPI1=4.48%; CPI2=47.39%. It is not alien from delta area and highland but it is alien among nations, highest CPI2 was in H’Mong group. It needs a project to prevent reasonably oral diseases.
Tooth Diseases
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Pupil
6.Study on subchronic toxicity of the receipt for the treament of cerebrovascular insufficiency in the liver and kidney
Pharmaceutical Journal 1999;282(10):15-16
The influence of some medications including medicaments originated plant on the liver and kidney functions and histologic changes in experiemental animal is carried out. The results shows that the liver and kidney function of rabit are not affected by the doses of 10-20 fold higher than clinical doses. Conclusion: These medications can be tried on the clinical at dose of less than 1.0 g/kg of bodyweight within 2 weeks with interval of 1- 2 weeks.
Toxicity
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Cerebrovascular Disorders
7.Evaluation of anti-inflammatory and analgesic effects of different formulations made from a massage tincture
Pharmaceutical Journal 2003;0(6):180-183
Two models: experimental traumatic edema (I) and 1% carrageenin-induced edema (II), were developed on rats for the study of the anti-inflammatory effects of drugs, I being superior to II as for the efficacity and appropriate treatment. The model for the study of the analgesic effect was developed by pressing on rat legs. Of the various prescriptions prepared from a traditional massage tincture, the formulations of 5% propylene glycol and emulgel were more effective in anti-inflammation and analgesia than the tincture itself.
Massage
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Anti-Inflammatory Agents
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Analgesics
8.Towards improvement of bét tam hoµng for use in the treatment of hemorrhoid at Cao Bang traditional medical Hospital89
Journal of Medicinal Materials - Hanoi 2003;8(2):89-91
Tam Hoang powder (constituents: rhizoma Coptidis, cortex Oroxyli, radix and caulis Fibraurea, CuSO4) was used for healing process after hemorrhoid treatment. Chemical analysis showed that the prescription contained alkaloids (two of them were berberine and palmatine), flavonoids, amino acids, tannin, sterols and reduced sugars. The powder fluid extract exhibited antimicrobial activities against 5 Gr (-) and 5 Gr (+) bacteria. Tam Hoang powder proved to have good healing effect on over 85% of 500 hemorrhoid patients.
Medicine, Traditional
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Hemorrhoids
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Chemistry
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Therapeutics
9.Effects of Morinda sp. on Liver Injury Induced by Paracetamol in Rats
Journal of Medicinal Materials - Hanoi 2003;8(5):139-142
Effects of aqueous extracts from the root of Morinda sp. were studied on liver injury induced by a high dose of paracetamol (acetaminophen) in rats. The results showed that the extract had a hepatoprotective effect at a dose of 10g/kg of body weight. The effect was similar to that of silymarin at a dose of 25mg/kg of body weight in terms of AST, ALT activities, total serum cholesterol and protein concentrations as well as macro-and microscopic histological studies of the liver.
Liver
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Acetaminophen
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Biochemistry
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animal experimentation
10.Dnodeno pancreas tectomy surgery: A propose of pancrea head cancer case
Journal of Medical and Pharmaceutical Information 2003;2():37-39
Dnodeno pancreas tectomy (Whipple surgery) is a rare surgery, in dicated mainly in pancrea head cancer (15-20%) in Europe and America. The head of pancrea, the duodenim, distant part of stomach and a past of jejunum were removed, digestive tract was recoustructed according child improvingly. A male patient of 45 year old age undergone the surgery in St. Paul Hospital. Post-operation: no pain, normal diet, normal urine. Discharged after 11 days, it is a complicated surgery with great risks, therefore it is necessary to prepare well pre-ocupationally. Advance anesthesia and resussitation, the technical improvements had contributed more in the success with a mortality of < 3%
Pancreas
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Whipple Disease
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Pancreas
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Therapeutics
;
surgery
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neoplasms
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