1.Relationship of chronic hepatitis C with interferon treatment and thyroid diseases
Chinese Journal of Endocrinology and Metabolism 2013;29(7):631-633
The article explores the relationship of the hepatitis C virus infection with interferon treatment and thyroid diseases and reviews the subtypes of the thyroid diseases.Autoimmune and nonautoimmune cases of thyroiditis are often seen in patients with chronic hepatitis C while undergoing interferon treatment,especially in females with positive thyroid autoantibodies.Graves' disease is very rare.The thyroid function may be as a transient thyrotoxicosis,then followed by hypothyroidism.The thyroid function in patients with nonautoimmune thyroiditis is usually easy to recover.
2.Evaluation of the effect of quality control circle on defect rate of perioperative health education
Chinese Journal of Practical Nursing 2016;32(16):1242-1246
Objective To evaluate the application effect of quality control circle on reducing the defect rate of health education in perioperative period of gynecologic surgery patients. Methods To carry out quality control circle activities, analysis of gynecological surgery patients in perioperative health education defect rate to the cause, the development of countermeasures, to achieve the purpose of continuous quality improvement. Results Before implementation health defects rate was 43.3%(303/700), after the implementation health education defect rate was 11.4%(223/1 950). The health defects rate before and after the implementation showed significant difference (χ2=8.387, P=0.004). The incidence of anxiety before and after the implementation was 11.8%(23/195) and 4.1%(8/195), the difference was significantly different (χ2=7.885, P =0.005). Conclusions To carry out the quality circle activity, can effectively reduce the perioperative health education defect rate and improve the quality of care and patient satisfaction, method is simple and easy to operate, it is worth clinical promotion.
3.Metastatic granulosa cell tumor showing pattern of sex cord tumor with annular tubules and Sertoli cell tumour.
Chinese Journal of Pathology 2013;42(3):206-207
Adult
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Cell Differentiation
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Female
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Granulosa Cell Tumor
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pathology
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surgery
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Humans
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Microtubules
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pathology
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Neoplasm Metastasis
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Neoplasms, Multiple Primary
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pathology
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surgery
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Ovarian Neoplasms
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pathology
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surgery
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Sertoli Cell Tumor
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pathology
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surgery
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Sex Cord-Gonadal Stromal Tumors
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pathology
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surgery
4.Cellular immunoresponse in patients with severe drug resistance-falciparum malaria and results of combined treatment of quinin, SMP and thymogen
Journal of Practical Medicine 2002;435(11):7-11
The study was carried out on 52 patients with severe falciparum malaria: 26 cases were treated by quinine, SMP in combination with Thymogene (control group). The results showed that: There is a reduction on cellular immune response in severe malaria. Thymogen has contributed to increase the immune response in comparison with this before treatment. Thymogen has contributed shortening time to defervescence, clearance of parasitaemia and coma duration in 2-days after treatment in comparison to control group. Thymogen also has contributed reducing mortality in severe malaria
Malaria
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thymogen
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Malaria, Falciparum
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therapeutics
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Pharmaceutical Preparations
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Drug Resistance
5.Progress of cancer therapy by magnetic nanocarriers for active target
Journal of International Oncology 2008;35(11):866-868
Great progress has been achieved for cancer therapy by magnetic nanocarriers for active target It has been proved that magnetic nanocarriers is a kind of potential tool for cancer prevention,diagnosis aIld treatment The active targeted nanocarriers are used for the tumor hyperthermia,medication and immunotherapy recently.
6.Determination of Palmatine Hydrochioride in Fuke Qianjin Tablets by HPLC
Traditional Chinese Drug Research & Clinical Pharmacology 2009;20(4):347-349
Objective To establish a HPLC method for determining of the content of palmatine hydrochloride in Fuke Qianjin Tablets. Methods HPLC was performed on Shimadzu-C18 column. The mobile phase consisted of 0.05 mol·L-1 sodium acid phosphate (pH=3, adjusted by phosphoric acid)-acetonitrile (72 : 28). The detection wavelength was at 265 nm. Results The linear correlation was in the range of 0. 051 μg~0. 255 μg(r=0. 999 9). The average recovery was 100. 04 %, and RSD=1.03 % (n=5). Conclusion The method is accurate and specific.
7.Outcome assessment of the medical relief policy in Anhui province
Chinese Journal of Hospital Administration 2010;26(9):648-651
The paper covered the implementation and social outcomes of the medical relief policy benefiting urban and rural residents in Anhui province. Based on analysis of problems identified, it proposed such recommendations: Enhance government financial support; improve the "safety net"mechanism of community hospitals; build a dynamic management system for those in need of medical relief; and tighten the linkage with social medical insurance.
8.Analysis of researches on food safety in China from 2000-2008
Chinese Journal of Medical Science Research Management 2010;23(5):337-339
Objective to reveal the research situation about food safety in China by analysing the articles published from 2000 to 2008. Methods bibliometrics were used to analyze the articles. The cooperation and the distribution of foundations were searched out from CBMdisc ( China scientific journal Database) with "food safety" as keywords. Results 1829 documents and 4,063 authors were identified. The rate of cooperation was 68.05% and the authors came from 32 provinces, autonomous regions and special administrative regions of China. 194 papers were supported by various kinds of fund. Conclusion Research on food safty is developing fast to meet the soring needs in this respect of the society.
9.Progress of bone marrow stromal cells and hematopoietic regulation
International Journal of Pediatrics 2011;38(1):71-73
Stromal cells are the important part of the bone marrow microenvironment. They provide a suitable environment for the self-renewal, proliferation and differentiation of the hematopoietic stem cells. Stromal cells include dendritic cells, macrophages, fibroblasts, endothelial cells and adipocytes. They secrete cytokines,extracellular matrix and provide direct cellular contaction to regulate hematopoiesis. Dysfunction of the stromal cells will lead to all kinds of hemopathy and immune system diseases directly.
10.Multidrug resistance associated protein 7 and its inhibitors
Journal of International Oncology 2010;37(11):821-824
Mechanism of reversing multidrug resistance (MDR) is associated with transport proteins.Up to date, researches mainly concern P-glycoprotein (P-gp) multidrug resistance associated protein 1(MRP1), breast cancer resistance protein (BCRP) inhibitors. Multidrug resistance associated protein 7(MRP7) is one of ABC transporters ,which belongs to multidrug resistance associated protein (MRP) subfamily. A certain number of studies have been conducted in recent years about it , however , they are relatively less than studies on P-GP,MRP1 and BCRP, et al. Structure of MRP7 has certain differences compared with that of other MRPs,and MRP7 mediates drug resistance to paclitaxel,vincristine,taxanes,etc. In recent years reported inhibitors include cepharanthine tyrosine kinase inhibitors、cyclosporine A,et al. MDR results from a variety of mechanisms so that researches on other transporters may provide extensive ways to reverse MDR.