2.Establishing seasonal and alert influenza thresholds in Cambodia using the WHO method: implications for effective utilization of influenza surveillance in the tropics and subtropics
Sovann Ly ; Takeshi Arashiro ; Vanra Ieng ; Reiko Tsuyuoka ; Amy Parry ; Paul Horwood ; Seng Heng ; Sarah Hamid ; Katelijn Vandemaele ; Savuth Chin ; Borann Sar ; Yuzo Arima
Western Pacific Surveillance and Response 2017;8(1):22-32
Objective: To establish seasonal and alert thresholds and transmission intensity categories for influenza to provide timely triggers for preventive measures or upscaling control measures in Cambodia.
Methods: Using Cambodia’s influenza-like illness (ILI) and laboratory-confirmed influenza surveillance data from 2009 to 2015, three parameters were assessed to monitor influenza activity: the proportion of ILI patients among all outpatients, proportion of ILI samples positive for influenza and the product of the two. With these parameters, four threshold levels (seasonal, moderate, high and alert) were established and transmission intensity was categorized based on a World Health Organization alignment method. Parameters were compared against their respective thresholds.
Results: Distinct seasonality was observed using the two parameters that incorporated laboratory data. Thresholds established using the composite parameter, combining syndromic and laboratory data, had the least number of false alarms in declaring season onset and were most useful in monitoring intensity. Unlike in temperate regions, the syndromic parameter was less useful in monitoring influenza activity or for setting thresholds.
Conclusion: Influenza thresholds based on appropriate parameters have the potential to provide timely triggers for public health measures in a tropical country where monitoring and assessing influenza activity has been challenging. Based on these findings, the Ministry of Health plans to raise general awareness regarding influenza among the medical community and the general public. Our findings have important implications for countries in the tropics/subtropics and in resource-limited settings, and categorized transmission intensity can be used to assess severity of potential pandemic influenza as well as seasonal influenza.
3.Early reports of epidemiological parameters of the COVID-19 pandemic
Keeley Allen ; Amy Elizabeth Parry ; Kathryn Glass
Western Pacific Surveillance and Response 2021;12(2):65-81
Background: The emergence of a new pathogen requires a rapid assessment of its transmissibility, to inform appropriate public health interventions.
Methods: The peer-reviewed literature published between 1 January and 30 April 2020 on COVID-19 in PubMed was searched. Estimates of the incubation period, serial interval and reproduction number for COVID-19 were obtained and compared.
Results: A total of 86 studies met the inclusion criteria. Of these, 33 estimated the mean incubation period (4–7 days) and 15 included estimates of the serial interval (mean 4–8 days; median length 4–5 days). Fifty-two studies estimated the reproduction number. Although reproduction number estimates ranged from 0.3 to 14.8, in 33 studies (63%), they fell between 2 and 3.
Discussion: Studies calculating the incubation period and effective reproduction number were published from the beginning of the pandemic until the end of the study period (30 April 2020); however, most of the studies calculating the serial interval were published in April 2020. The calculated incubation period was similar over the study period and in different settings, whereas estimates of the serial interval and effective reproduction number were setting-specific. Estimates of the serial interval were shorter at the end of the study period as increasing evidence of pre-symptomatic transmission was documented and as jurisdictions enacted outbreak control measures. Estimates of the effective reproduction number varied with the setting and the underlying model assumptions. Early analysis of epidemic parameters provides vital information to inform the outbreak response.
4.How can we better support the public health emergency response workforce during crises?
Amy Elizabeth Parry ; Samantha M Colquhoun ; Emma Field ; Martyn D Kirk ; David N Durrheim ; Tambri Housen
Western Pacific Surveillance and Response 2021;12(4):01-03
For public health response to be effective, it is essential that we identify support mechanisms for people working in challenging response environments. The Regional Office for the Western Pacific needs programmes, such as Field Epidemiology Training Programmes, to ensure sustained workforce development. However, during crises a modified mentorship-like program may foster temporary support and empowerment within the workforce.
5.A descriptive assessment of the National Institute of Public Health’s role in supporting the COVID-19 response in Cambodia, 2020–2021
Srean Chhim ; Wuddhika In Vong ; Kimsorn Pa ; Chanboroth Chhorn ; Tambri Housen ; Amy Elizabeth Parry ; Wim Van Damme ; Por Ir ; Chhorvann Chhlea
Western Pacific Surveillance and Response 2023;14(1):60-66
Objective: This paper examines the contributions made by the National Institute of Public Health to Cambodia’s response to the coronavirus disease (COVID-19) pandemic during 2020–2021.
Methods: The activities conducted by the Institute were compared with adaptations of the nine pillars of the World Health Organization’s 2020 COVID-19 strategic preparedness and response plan. To gather relevant evidence, we reviewed national COVID-19 testing data, information about COVID-19-related events documented by Institute staff, and financial and technical reports of the Institute’s activities.
Results: The main contributions the Institute made were to the laboratory pillar and the incident management and planning pillar. The Institute tested more than 50% of the 2 575 391 samples for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing and provided technical advice about establishing 18 new laboratories for SARS-CoV-2 testing in the capital city of Phnom Penh and 11 provinces. The Institute had representatives on many national committees and coauthored national guidelines for implementing rapid COVID-19 testing, preventing transmission in health-care facilities and providing treatment. The Institute contributed to six other pillars, but had no active role in risk communication and community engagement.
Discussion: The Institute’s support was essential to the COVID-19 response in Cambodia, especially for laboratory services and incident management and planning. Based on the contributions made by the Institute during the COVID-19 pandemic, continued investment in it will be critical to allow it to support responses to future health emergencies in Cambodia.
6.Contribution of the Australian field epidemiology training workforce to the COVID-19 response, 2020
Amy Elizabeth Parry ; Charlee Law ; Davoud Pourmarzi ; Florian Vogt ; Emma Field ; Samantha Colquhoun
Western Pacific Surveillance and Response 2022;13(4):86-90
The aim of this study was to describe the scope of the Australian Field Epidemiology Training Programme's contributions to the COVID-19 response during the first 10 months of the pandemic, to assist with quantifying the impact they have had during the pandemic and inform future Master of Applied Epidemiology programme learning priorities.