1.Detection of Infectious Fungal Diseases of Frogs Inhabiting in Korea.
Suk KIM ; Ahn Heum EOM ; Daesik PARK ; Nam Yong RA
Mycobiology 2008;36(1):10-12
In recent years, there has been a rapid decrease in amphibian populations worldwide, and infectious diseases have been associated with this decline. Diseased frogs inhabiting Korea were collected from fields, and the diseases were identified by morphological and molecular analyses. Two fungal diseases-saprolegniasis and chromomycosis-were detected in the frogs. Saprolegniasis caused by Saprolegnia spp. was found in Rana plancyi chosenica from Gangwon-do and Rana huanrenensis from Chungbuk. Chromomycosis, which is caused by infection with Cladosporium cladosporioides, was detected in Rana catesbeiana from Busan.
Amphibians
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Chromoblastomycosis
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Cladosporium
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Communicable Diseases
;
Korea
;
Rana catesbeiana
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Ranidae
;
Saprolegnia
2.The expression of subcloned human immunodeficiency virus genes microinjected into the amphibian oocyte.
Hoon CHOI ; Hong Kyun LEE ; Chae Gwan LEE ; Sung Goo KANG
Korean Journal of Obstetrics and Gynecology 1991;34(4):494-507
No abstract available.
Amphibians*
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HIV*
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Humans*
;
Oocytes*
3.Dynamic cell transition and immune response landscapes of axolotl limb regeneration revealed by single-cell analysis.
Hanbo LI ; Xiaoyu WEI ; Li ZHOU ; Weiqi ZHANG ; Chen WANG ; Yang GUO ; Denghui LI ; Jianyang CHEN ; Tianbin LIU ; Yingying ZHANG ; Shuai MA ; Congyan WANG ; Fujian TAN ; Jiangshan XU ; Yang LIU ; Yue YUAN ; Liang CHEN ; Qiaoran WANG ; Jing QU ; Yue SHEN ; Shanshan LIU ; Guangyi FAN ; Longqi LIU ; Xin LIU ; Yong HOU ; Guang-Hui LIU ; Ying GU ; Xun XU
Protein & Cell 2021;12(1):57-66
Ambystoma mexicanum/immunology*
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Amputation
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Animals
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Biomarkers/metabolism*
;
Blastomeres/immunology*
;
Cell Lineage/immunology*
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Connective Tissue Cells/immunology*
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Epithelial Cells/immunology*
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Forelimb
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Gene Expression
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High-Throughput Nucleotide Sequencing
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Humans
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Immunity
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Peroxiredoxins/immunology*
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Regeneration/immunology*
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Regenerative Medicine/methods*
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Single-Cell Analysis/methods*
4.Antiplasmodial and Cytotoxic Activities of Toad Venoms from Southern Amazon, Brazil.
Felipe Finger BANFI ; Karla de Sena GUEDES ; Carla Regina ANDRIGHETTI ; Ana Carolina AGUIAR ; Bryan Wender DEBIASI ; Janaina da Costa NORONHA ; Domingos de Jesus RODRIGUES ; Gerardo Magela Vieira JÚNIOR ; Bruno Antonio Marinho SANCHEZ
The Korean Journal of Parasitology 2016;54(4):415-421
The drug-resistance of malaria parasites is the main problem in the disease control. The huge Brazilian biodiversity promotes the search for new compounds, where the animal kingdom is proving to be a promising source of bioactive compounds. The main objective of this study was to evaluate the antiplasmodial and cytotoxic activity of the compounds obtained from the toad venoms of Brazilian Amazon. Toad venoms were collected from the secretion of Rhinella marina and Rhaebo guttatus in Mato Grosso State, Brazil. The powder was extracted at room temperature, yielding 2 extracts (RG and RM) and a substance ('1') identified as a bufadienolide, named telocinobufagin. Growth inhibition, intraerythrocytic development, and parasite morphology were evaluated in culture by microscopic observations of Giemsa-stained thin blood films. Cytotoxicity was determined against HepG2 and BGM cells by MTT and neutral red assays. The 2 extracts and the pure substance ('1') tested were active against chloroquine-resistant Plasmodium falciparum strain, demonstrating lower IC₅₀ values. In cytotoxic tests, the 2 extracts and substance '1' showed pronounced lethal effects on chloroquine-resistant P. faciparum strain and low cytotoxic effect, highlighting toad parotoid gland secretions as a promising source of novel lead antiplasmodial compounds.
Amphibian Venoms*
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Animals
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Biodiversity
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Brazil*
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Bufo marinus
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Malaria
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Neutral Red
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Parasites
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Plasmodium falciparum
5.Study on the origin of Rana temporaria for quality Oviduetus Ranae.
Yi-ping LI ; Jin-gang ZHANG ; Miao LI ; Chun-mei LIU ; Da-cheng JIANG ; Ming-lu DENG
China Journal of Chinese Materia Medica 2003;28(1):15-17
OBJECTIVETo determine the origin of Rana temporaria for quality Oviduetus Ranae in the light of historical documents and modern researches on the classification of Rana temporaria chensinensis.
METHODWorks of Chinese meteria medica of all ages, related historical documents and reports from home and abroad on researches of R. temporaria chensinensis were consulted, sorted out, analyzed and summarized.
RESULTThe original Shange recorded in the works of Chinese meteria medica is R. temporaria chensinensis, which is the independent species, not one of species of European forest frogs. R. temporaria chensinensis is divided into 4 subspecies: R. temporaria chensinensis, Lanzhou, Kangding, and Changbaishan. The origin of R. temporaria is Changbaishan subspecies of R. temporaria chensinensis.
CONCLUSIONChangbaishan subspecies of R. temporaria chensinensis is determined as the origin for quality Oviduetus Ranae.
Animals ; Female ; History, 18th Century ; History, 19th Century ; History, 20th Century ; History, Ancient ; Materia Medica ; history ; isolation & purification ; Oviducts ; chemistry ; Rana temporaria ; anatomy & histology ; Ranidae ; anatomy & histology ; classification ; Species Specificity ; Terminology as Topic
6.Two Children with Nontyphoidal Salmonellosis Assumed by Pets.
Jong Deok KIM ; Seong Yeol CHOI ; Dong Soo KIM ; Ki Hwan KIM
Korean Journal of Pediatric Infectious Diseases 2013;20(1):41-45
Nontyphoidal Salmonella are gram negative bacilli organism, which may induce systemic infection such as febrile enteritis, bacteremia, and osteomyelitis. Main route of infection is known as food but also possible through reptile, amphibian, and fish raised as pets in the house. There is no known cases report of Salmonella infection through pets in Korea and also rare in the overseas. We report 2 patients who visited Severance children's hospital with chief complaint of fever and diagnosed as nontyphoidal salmonellosis. Each case had a history of raising turtle or tropical fish with possibility of Salmonella infection through these pets. Increasing incidence of raising pet reptile and fish lately, contact precaution and proper prevention and control of Salmonella infection of these pets especially in children under 5 years old are necessary due to higher risk of serious complications of salmonellosis.
Amphibians
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Bacteremia
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Child
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Enteritis
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Fever
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Fishes
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Humans
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Incidence
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Korea
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Osteomyelitis
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Reptiles
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Salmonella
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Salmonella Infections
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Turtles
7.Food-borne Parasitic Diseases.
Journal of the Korean Medical Association 2004;47(6):496-507
This article briefly reviews parasites transmitted by food materials and their diseases in Korea. They are taxonomically classified into 31 species of helminths, which include nematodes(6 species), trematodes(20), cestodes(6), and 1 species of protozoan. The food materials serving as the source of human infections are fishes, snails, crustacea, amphibia, reptiles, and mammals. These parasites include those that have been veiled by the previously common and well-known parasites such as Ascaris and Trichuris, and those that have been newly identified as human-infecting parasites. For prevention of these infections, avoidance of raw or improperly cooked foods is the most important strategy.
Amphibians
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Ascaris
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Crustacea
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Fishes
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Foodborne Diseases
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Helminths
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Humans
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Korea
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Mammals
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Parasites
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Parasitic Diseases*
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Reptiles
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Snails
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Trichuris
9.A Case of Peritoneal Dialysis-related Peritonitis Caused by Aeromonas Hydrophila in the Patient Receiving Automated Peritoneal Dialysis
Hyun Jin KIM ; Hyun Sun PARK ; Eunsin BAE ; Hae Won KIM ; Beom KIM ; Kyoung Hyoub MOON ; Dong Young LEE
Electrolytes & Blood Pressure 2018;16(2):27-29
Peritoneal dialysis (PD)-related peritonitis is a major cause of injury and technique failure in patients undergoing PD. Aeromonas hydrophila is ubiquitous in the environment, and is a Gram-negative rod associated with infections in fish and amphibians in most cases; however, it can also cause opportunistic infections in immunocompromised patients. We report a case of A. hydrophila peritonitis in a 56-year-old male on automated PD. Peritonitis may have been caused by contamination of the Set Plus, a component of the automated peritoneal dialysis device. Although Set Plus is disposable, the patient reused the product by cleansing with tap water. He was successfully treated with intraperitoneally-administered ceftazidime and has been well without recurrence for more than 2 years.
Aeromonas hydrophila
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Aeromonas
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Amphibians
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Ceftazidime
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Humans
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Immunocompromised Host
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Male
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Middle Aged
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Opportunistic Infections
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Peritoneal Dialysis
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Peritonitis
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Recurrence
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Water
10.Chemical constituents from Bufonis periostracum and their antitumor activity in vitro.
Huimin GAO ; Xiyan WU ; Zongyun LI ; Yun YOU ; Yi ZHANG ; Zhimin WANG
China Journal of Chinese Materia Medica 2011;36(16):2207-2210
Eight compounds were isolated from Bufonis periostracum by repeated column chromatography on silica gel, ODS and Sephadex LH-20 and their structures were characterized as palmitatic acid cholesteryl ester (1), cholesterol (2), 5alpha, 8alpha-epidioxycholesta-6-en-3beta-ol (3), cholest-5-en-3beta, 7beta-diol (4), cholest-7-en-3beta, 5alpha, 6beta-triol (5), 3-octaddecyloxy-1, 2-propanediol (6), isisamide (7) and bufothionine (8) on the base of spectral analysis. Compounds 1-8 were isolated from Bufonis periostracum for the first time and compounds 3, 5, 6, 7 were obtained from Bufo bufo gargarizans and Bufo genus for the first time. The bioassays showed all tested samples displayed no antitumor activity against the cell lines such as A549, BeL 7402, HGC-27 and HL-60, except the control compound bufalin.
Animals
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Antineoplastic Agents
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pharmacology
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Bufo bufo
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metabolism
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Bufonidae
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metabolism
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Humans