1.Amiodarone induced photosensitivity.
Bang Soon KIM ; Jai Il YOUN ; Yun Shik CHOI
Korean Journal of Dermatology 1991;29(5):622-626
No abstract available.
Amiodarone*
2.Clinical Observation on Amiodarone Treatment for Critical Arrhythmia in Children.
Ki Soo KIM ; Chung Il NOH ; Jung Yun CHOI ; Yong Soo YOON ; Chang Yee HONG
Journal of the Korean Pediatric Society 1989;32(6):765-772
No abstract available.
Amiodarone*
;
Arrhythmias, Cardiac*
;
Child*
;
Humans
4.Torsade de Pointes Induced by Long-Term Oral Amiodarone Therapy.
Jong Ho NAM ; Yoon Jung CHOI ; Min Kyu KANG ; Sung Yun JUNG ; Su Mi KIM ; Sang Hee LEE ; Dong Gu SHIN
Yeungnam University Journal of Medicine 2011;28(1):90-93
Although amiodarone is generally regarded as safe with a low incidence of associated arrhythmias, torsade de pointes (TdP) has been observed usually in the presence of predisposing factors. We report a case of amiodarone-induced TdP after long-term administration of a low dose of oral amiodarone in the absence of predisposing factors.
Amiodarone
;
Arrhythmias, Cardiac
;
Incidence
;
Torsades de Pointes
5.A Case of Amiodarone Keratopathy.
Seung Jin LEE ; Chang Kyu PARK ; Hyun Chol KIM ; Eung Joo KIM ; Jin Won KIM ; Jin Soo LEE ; Hyung Joon YIM ; Jung Chun AHN ; Eun Mi LEE ; Hong Seog SEO ; Wan Joo SHIM ; Dong Joo OH ; Young Moo RO
Korean Circulation Journal 1998;28(8):1382-1386
Amiodarone hydrochloride is a benzofuran derivative used for the treatment of cardiac arrhythmias. It is associated with a number of side effects, including thyroidopathy, neuropathy, cutaneous pigmentation, photosensitivity, pulmonary toxicity, hepatotoxicity and keratopathy. Amiodarone keratopathy hasbeen classified into four stages. Corneal pigmentation varies from stage 0, which is a clear cornea without pigment deposition, to stage 3, that is, corneal pigmentation encroaching upon the pupil. We present a case of amiodarone induced keratopathy of stage 3 who received low dose oral amiodarone maintain therapy.
Amiodarone*
;
Arrhythmias, Cardiac
;
Cornea
;
Pigmentation
;
Pupil
6.Amiodarone-induced Pulmonary Toxicity within a Short Period of the Initiation of Amiodarone Therapy: A Case Report.
Woo Jin JANG ; Hae Ri CHON ; Jin Sung JUNG ; Seung Hyun YOO ; Kyu Han KOH ; Young Min KOH ; Jung Hyuk KIM
The Korean Journal of Critical Care Medicine 2011;26(2):117-121
Amiodarone is one of the most commonly prescribed antiarrhythmic drug for almost all atrial or ventricular arrythmias. Amiodarone-induced pulmonary toxicity (APT) was first described in 1980 and has potentially serious side effects that are believed to develop in 5% of patients. In general, APT occurs only when high amiodarone doses are used for a long time. However, during short-term therapy of amiodarone, APT is rarely reported. In this report, we describe a case of amiodarone-induced pulmonary toxicity after a short course of amiodarone therapy for atrial fibrillation.
Amiodarone
;
Arrhythmias, Cardiac
;
Atrial Fibrillation
;
Dimaprit
;
Humans
7.Therapeutic Trial of Low Dose Amiodarone in Ventricular Arrhythmia.
In Ju KIM ; Won Tae CHUNG ; Jeong Wan KIM ; Deog Hyeon SON ; Young Woo SHIN ; Yeong Kee SHIN
Korean Circulation Journal 1988;18(3):455-461
The antiarrhythmic efficacy if low dose amiodarone treatment was studied in 30 cases of ventricular premature beats(VPBs). Amiodarone was administered 600mg daily in three divided doses for for initial 7-10 days as loadihg dosage,then 100-200mg once daily as maintenance. The results obtained were as follow : 1) The complete control of VPBs was achieved by amiodarone treatment in 90%, 27cases of 30 cases(all 11 cases with simple VPBs and 16 cases of the remainders with complex VPBs). 2) The QT interval and QTc were significantly prolonged, whereas heart rate was reduced significantly after amiodarone treatment. 3) In 27 cases of responder, the frequency of VPBs began to decrease overtly 2-3 days after amiodarone administration, then relatively stablized in 6 days, and complete cnotrol of VPBs was achieved in all cases about 10 days after treatment. 4) No significant side-reaction was observed except the decrease of serm T3 level after treatment.
Amiodarone*
;
Arrhythmias, Cardiac*
;
Heart Rate
;
Selective Estrogen Receptor Modulators
8.Relation between the Efficacy of Amiodarone on Chronic Atrial Fibrillation and Left Atrial Size and Fibrillatory Wave Form.
Young Kyu HONG ; Hong Seog SEO ; Dong Joo OH ; Young Moo RO
Korean Circulation Journal 1989;19(1):125-131
To assess the efficacy of amiodarone on chronic atral fibrillation(AF) and to evaluate the relation between the ability to convert AF to sinus rhythm (SR) with amiodarone therapy and left atrial(LA) size and atrial fibrillatory wave forms, 22 patients with AF, aged 40 to 60 years(mean 47.5 years), were studied. Nine patients(40.9%) had mitral valvaular heart disease, 6(27.3%) hypertension, 5(18.2%) lone AF and 2 (9.1%) cadiomyopathy. Amiodarone therapy with either 600mg for 1 week, 200mg for 4 weeks in 5 consecutive patients, or 800mg for 1 week, 400mg for 4 weeks and 200mg for 6 weeks in 17 patients, converted AF to SR in 9(40.9%) patients 3 to 6 weeks after amiodarone was started on. In either group, patients who achieved conversion had smaller LA size(mean 43.7mm) than those who failed conversion(mean50.2mm)(P<0.05). Those who had LA size less than 45mm achieved conversion of AF to SR in 70%, comparing to 16.7% in patients with LA size more than 46mm(P<0.05). Among patients who achieved conversion, LA size was less than 46mm in 77.8% comparing to 23.1% in patients who failed conversion on Amiodarone. Those with coarse AF(46.2mm), althogh the difference was not significant statistically. There was no converstion in patients with LA size greater then 58mm and in patients with coarse AF who concomittantly had MVD. These findings suggest that the efficacy of amiodarone was related to LA size, and to the atrial fibrillation wave form in patients with mitral valvular heart disease.
Amiodarone*
;
Atrial Fibrillation*
;
Heart Diseases
;
Heart Valve Diseases
;
Humans
;
Hypertension
9.Amiodarone Induced Keratopathy.
Jun Ho HEO ; Ji Young KIM ; Chul Ho KIM
Journal of the Korean Ophthalmological Society 1999;40(4):921-925
Amidarone hydrochloride, benzofuran derivatives, particularly effective for the treatment of arrythmias by prolong the duration of the action potential in all cardiac-conducting tissues. We studied the 25 patients with typical amiodarone keratopathy, retrospectively. In 25 patients, ten patients developed grade 1, eleven patients developed grade 2, and four patients developed grade 3 keratopathy. They complained of decreased best corrected visual acuity(1 patient), halos(1 patient), hypothyroidism(3 patients), pulmonary toxicity(2 patients), thpatic dysfunction(5 patients) and sleep dusturbance(3 patients). Therefore ophthalmologists should be alert for the complications of amiodarone and regular careful slit-lamp examination will be helpful in minimizing amidarone toxicity.
Action Potentials
;
Amiodarone*
;
Arrhythmias, Cardiac
;
Humans
;
Retrospective Studies
10.High CT Attenuation of Liver Due to Accumulation of Amiodarone: Report of Two Cases.
Kang Hyuk LEE ; Jong Beum LEE ; Young Hee CHOI ; Yang Soo KIM ; Kun Sang KIM
Journal of the Korean Radiological Society 1998;39(4):769-771
Amiodarone is an antiarrhythmic drug containing 37% iodine by weight ; during long-term therapy the drugaccumulates in the liver, lung and various other organs. We describe two cases in which high attenuation of theliver due to the accumulation of amiodarone was seen on abdominal CT.
Amiodarone*
;
Iodine
;
Liver*
;
Lung
;
Tomography, X-Ray Computed