1.Survey on the prevalence of hypertention and risk factors among the people above 30 year-old of Bayankhongor province
Altanzaya D ; Amgalan D ; Zulgerel D ; Ser-Od KH ; Davaa G
Mongolian Medical Sciences 2012;160(2):51-56
BackroundThe goal of the survey was to determine the prevalence of hypertension and common modifiable risk factors which is constantly increases and in highly lead of blood circulating system diseases among the people of Baynkhongor province in recent years, and also to find a reasonable ways to improve preventive actions for long life expectancy of the province residents.GoalThe goal of the survey was to determine the prevalence of hypertension and common modifiable risk factors among the people above 30 years old of Bayankhongor province.Objectives:1. To determine the prevalence of hypertension among the people above 30 years old of Bayankhongor province2. To determine the risk factors for hypertensionMaterials and Method:The cross-sectional survey used WHO STEPS survey methodology adapted to the countrys specifics. A total of 373 randomly selected above 30 year-old residents involved to the survey that all represented by ages, gender etc.Results:The survey result showed that about 41.3% of the target population who involved in the survey has the prevalence of hypertension and with no difference in all regions too. Men had significantly higher prevalence of hypertension compared to women as well (p=0.029), andit would occurs and happens more with the aging. Total of 34.6% of the target population who have the prevalence of hypertension (p=0.0001) have diagnosed and whereas men at risk about 66%. The survey result showed that the consumption of the pernicious habits of the population is high, and average daily serving of fruits and vegetables were (1.64 unit) once 3 more times less than the WHO recommendation. Daily salt intake was 9.8 grams per person (2 more times higher than the WHO recommendation) and nearly one in two persons were at increased risk for physical inactivity.Conclusions:The survey result showed that about 41.3% of the target population who involved in the survey has the prevalence of hypertension. In conclusion, the summary of combined hypertension risk factors demonstrates that 2 in 3 (65.9%) adults have 1-2 risk factors and 1 in 3 (30%) adults have three or more common modifiable risk factors. Twice as many young men (aged 30-49 years) than women have high 3 more risk factors.
2. PHARMACOLOGICAL TREATMENT OF NON-ACTION IN VIVO ENVIRONMENT AS RESEARCH
Munkhtsatsral TS ; Otgontsetseg T ; Enkh-amgalan P ; Enkhgerel D
Mongolian Pharmacy and Pharmacology 2015;6(1):36-39
AbstractIntroduction: Effects of medicine have many influential pharmaceutical and non-pharmaceutical factors. Term, “factors of medicine had been out because clinical research had proven that effect of medicine and reaction depends on medicine preparation technology, type of medicine, method to apply medicine. Prior to that, it was considered that quality of medicine depends on physical and chemistry conditions of medical ingredients, amount of active ingredients, etc. Bio digestion of medicine is an important criteria to take correct treatment, to reduce side effects in order to providing medical safety, to improve medicine quality, and to increase treatment impact. This study is about to prove that medical effect depends on medical factor particularly type of medicinePurpose: Aim is to study drug medical dissimilarity action in vivo enviromentMaterials and Methods: diuretics pharmacology tests 18-24gr 40 pieces weighting Balb /cshugamyn conducted on mice. Test "Monos" pharmacological sector in cooperation with the Institute for Research on drugs. Statistics by SPSS-20 software implementation and results of student criteria (p<0.05) was recognized and confirmed by one way ANOVA.Research is completedthe diuretics in the following the next sequence (Tryeindlinburg, 1980) 1. The research was conducted prior to the start of the test animals 0,3ml / 20gr doses of saline solution (NaCl 0.9%) treated with oral fluid pressure generated2. The research groups of injecting drug predicted doses experimental animals to drink5.3. Drinking the drug preparations 2.5 hours after the 30-minute intervals during the test animals urine test groups amount of urine of animals (p <0.05) compares.Result: Experimental animals, urine collected during the 30-minute interval of 2.5 hours, urine volume between the groups was compared with the control group.Administered medications, a comparative study of the Russian Federation " X1" acting industry furosemid make urinate "X2" Company "X3" LLC furosemid (p <0.05) compared to the control groups entails strong drugs furosemide make urinate consistent.Table form of furosemide drugs that acts comparative study of the Russian Federation "X1" acting industry furosemide make urinate "X4" Pharm Co Ltd furosemide (p <0.05) entails experimental groups with the control group furosemide make urinate strong comparison function (p <0.05)Conclusion:Medical activity that was different shows drug medical dissimilarity action, when comparing between types of pyroselid drug in various industries.Key words: Tablet form, active treatment, furosemide, injection, tablet, drug therapy acts as
3.Assessing the cardio-ankle-vascular index, its influnencing factors and framingham heart scores in comparatively healthy 20-40 age adults of Ulaanbaatar city
Byambasuren V ; Sumya TS ; Enkh-Amgalan D ; Bilegjargal B ; Odkhuu E ; Munkhzol M
Mongolian Medical Sciences 2013;163(1):15-19
BackgroundOut of total 209550 cases of cardiovascular diseases in 2011, 66,7% were newly registered cases.Cardiovascular diseases are the number one cause of mortality in Mongolia; an estimated 6291 peopledied from CVDs in 2011, representing 36.7% of all deaths. It shows that CVD mortality level is higherthan in other countries.Materials and MethodsOur survey is a cross sectional study. We have investigated 600 people of the age of 20-40 whowere randomly selected from 6 urban districts of Ulaanbaatar city. With a permission #4 issued bythe Medical Ethics Control Committee of the Ministry of Health on 25th March 2011, our survey wascarried out between the 1st of July 2011 and the 1st of January 2012 based on the Functional DiagnosticLaboratory, Department of Physiology and Pathophysiology, School of Biomedicine, Health SciencesUniversity of Mongolia.ResultsThe CAVI was significantly higher (p<0.001) in 30-40 aged adults (6.68, 95% CI 6.58-6.78) than 20-29 aged adults (6.42, 95% CI 6.32-6.52). Also CAVI has a direct correlation with the cholesterol level(p<0.05, R2=0,011). Serum cholesterol, triglycerides and LDL levels were significantly higher (p<0.05)in men than women. Framingham Heart Score was in the normal range in 99.2% of the participantswith 4 cases having the score of 10% or higher representing a risk score.ConclusionsDislipidemia, overweight and obesity in young adults are the main causes of vascular dysfunctionsleading to cardiovascular diseases. Thus, the findings of the study demonstrate that helping youths todevelop healthy lifestyles including healthy eating and physical activities shall play a critical role for theprevention and intervention programs designed for development of healthy behavior and lifestyle fromchildhood, especially for the male population, are vital for fulfillment of this role.
4.Relationship between respiratory and circulatory diseases among adults and air temperature
Nyam-Osor D ; Oyunchimeg M ; Nyamsuren L ; Amgalan G ; Enkhtuya P ; Burmaajav B
Mongolian Medical Sciences 2012;162(4):36-42
BackgroundHuman-induced climate change will affect the lives of most populations in the next decade and beyond. The impact of meteorological conditions on human health has been reported globally. There is a need to conduct surveys for correlation between climate change and human health.GoalTo study the impact of air temperature on human health in selected aimags and city districts.Materials and MethodsIn order to study how climate change and air quality parameters affect human health we selected Zavhan, Selenge, Dornod, and Umnugobi aimags which represent different climate zones and 2 districts of Ulaanbaatar city during 2009-2011. All data for respiratory system disease J00-J99, circulatory system disease I00-I99, were collected from soum, district’s hospital, and aimag and soum’s Department of health.ResultsDuring the study period, a total number of 8649 incidences of respiratory disease are registered. From them 74.2 percent are influenza and pneumonia (J09-J18), 17.6 percent are other acute lower respiratory infections (J20- J22), and 8.2 percent are asthma (J45-J45.9). For cardiovascular disease 15288 incidences are registered. From them 65.6 percent are hypertensive disease (I10-I15), 23.6 percent are ischemic heart disease, and 10.8 percent are cerebrovascular diseases (I60-I69). The lower the air temperature, higher the incidence of influenza and pneumonia, acute lower respiratory infections, hypertensive, and ischemic heart disease.ConclusionsCold weather is correlated with a higher incidence of respiratory and cardiovascular diseases.
5. Analyzes on dislipidemia in Govi-Altai population
Erkhemtsetseg G ; Dorjdagva D ; Enkh-Amgalan N ; Tuvshinbileg G ; Munkhjargal O
Health Laboratory 2016;5(1):18-23
Background:We determined lipid parameters which are the leading causes of developing cardiovascular diseases and atherosclerosis and investigated the increased serum triglyceride level which is referred to as atherogen triad , decreased high-density lipoprotein and increased low- density lipoprotein associating with age and sex.Method:237 people who were done lipid level parameter tests in the Central Hospital Laboratory were involved in the study. We identifed cholesterol, triglyceride, lowdensity lipoprotein (LDL) and high-density lipoprotein ( HDL) (COBASC-311,ROCHE,Germany) which are the lipid parameters using full automatic apparatus .Results:While serum cholesterol level increased in the ages between 40-60 and has a tendency to decrease in the further, HDL level was decreasing as the age grew. Serum LDL level has strong direct relevance to cholesterol (r=0.720, p<0.01) and weak relevance to triglyceride (r=0.189,p<0.01). As for the sex, high- density lipoprotein level decreased for men with statistical importance (p<0.05) and there was no signifcant difference in other parameters. LDL level increased for 81.8% , increased cholesterol for 51.1%, raised triglyceride for 27.9% comparing with the normal rate but HDL level was decreased for 32.2% of the participants in the study. These changes mostly occurred at the ages of 40-60. Atherogen triad occurred for 16.5% of the participants and 13(33.3%) of whom were male and 26(66.7%) female.Conclusion:LDL and cholesterol level raised more than the normal rate comparing with other lipid parameters particularly as for 40-60 aged people and atherogen triad which leads to develop atherosclerosis occurs in 16.5% of all adults in the study.
6.Tannin rich medicinal plants
Enkh-Amgalan P ; Telmen D ; Altan-Erdene N ; Selenge E
Mongolian Pharmacy and Pharmacology 2022;20(1):78-85
Abstract
Secondary metabolites present in the plants are predominantly responsible for treating various ailments. Secondary metabolites are also called as plant constituents or natural compounds which exert significant pharmacological and toxicological effects in humankind. The chemical compounds present in the plant sources are categorized as primary and secondary metabolites based on the chemical structure and biosynthetic derivation. These substances are called plants secondary metabolites. One of the most important of secondary metabolites is Tannins. Tannins are phenolic compounds, secondary metabolites of plants widespread in terrestrial and aquatic natural environments. As they can be found in plenty of plants and herbs, they have been traditionally used for medicinal and other purposes, such as the leather industry. This fact is explained by the fact that they exert plenty of different biological activities and, thus, they entail a great potential to be used in the food, nutraceutical, and pharmaceutical industry.
Among the biological activities of tannins, the most relevant ones are antioxidant, anti-inflammatory, anti-diabetic, cardioprotective, healing and antimicrobial (antiviral and antibacterial)
Consequently, this review article is directed towards the description of the biological activities exerted by tannins as they could be further extracted from by-products of the agri-food industry to produce high-added-value products.
7.Correlation between hair elements and intelligence quotient in children with attention deficit/hyperactivity disorder
Amgalan B ; Tovuudorj A ; Nasantsengel L ; Yanjinlkham B ; Tserendolgor O ; Saruul D ; Erdenetuya G
Mongolian Medical Sciences 2020;191(1):13-18
Introduction :
Attention-Deficit/Hyperactivity Disorder (ADHD) is a disorder that occurs during childhood
development, which presents with signs of reduced attention and hyperactivity [1]. Necessary
nutrients, such as trace minerals, including manganese, iron, zinc, iodine, selenium, copper, and
chromium, are associated with changes in neuronal function that can lead to adverse effects on
behavior and learning [2]. In addition to these, social, emotional, behavioral problems, and cognitive
impairments such as executive dysfunctions are common in ADHD [3].
Goal:
To evaluate the hair elements and intelligence quotient in children with ADHD.
Materials and Methods:
This is a cross-sectional comparative study conducted at elementary schools of Ulaanbaatar city. All
in all 60 children of both genders aged between 7-12 years old were included in the study. Children
were divided into two groups as children with ADHD group and a control group. Each group had 30
children. For assessment of emotional Intelligence EQ-i:YV - Emotional Quotient Inventory: Youth
Version (Bar-On & Parker, 2000; it ad. Sannio Fancello, & Cianchetti, 2012) was used. Scalp hair
samples were randomly collected from approximately ten sites around both sides of posterior parietal
eminences and external occipital protuberance. Samples were then packed at room temperature and
submitted for laboratory analysis. The study was approved by the Research Ethics Committee of
Mongolian National University of Medical Sciences (Reg. No. 2018/Д-10).
Results:
The IQ of children with ADHD group were 85.03±16.86 p<.0001 and the IQ of control group
=108.9±21.22, p<.0001. We identified hair minerals such as Mg, Zn, Pb, Se, Mn. We have then
compared to each group and normal ranges of ages. ADHD group and the control group had Pb
concentration that was slightly higher and inversely Mg concentration was slightly lower (r=-0.502,
p=.005). Concentration of Pb, IQ were directly opposite (r=-0.38, p=.03).
Conclusion
1. IQ was lower in the ADHD group compared to control group 85.03±16.86 p<.0001, monitored
group 108.9±21.22, p<.0001.
2. The group with ADHD had lower Mg, Zn, and higher Pb, Se, Mn (p<.0001). The IQ decreased
when there was increased Pb and decreased Mg.