Objective: To investigate the effects of prallethrin on renal dysfunction biomarkers, antioxidant enzyme activities and lipid peroxidation (LPO) in rats and the protective effect of Origanum majorana essential oil. Methods: Rats were divided into four groups of seven rats in each group: (I) received only olive oil, (II) treated with 64.0 mg/kg body weight prallethrin (1/10 LD