According to information of WHO, stroke is one of the leadership reasons for death and loss of ability to work. For stroke patients on evidence based models are important and necessary to know early treatment within short time to reducing care with the help of public supports and their care also very important. Following principle especially after stroke period and restoration is very important forprofessional units, treatment and nursing continuously can serve for common result. Cardiff School of Nursing is able to serve for patients with nursing care and it will be more resultative. From world neurology association is very important to prepare specialists who had spiritual level and to form training curriculum. From world neurology association is very important to prepare specialists whohad spiritual level and to form training curriculum.We provided the quality of study according to documents of Hennessy-Hicks methods. In this study participated 51 students of Darkhan branch medical school, and 210 graduates from Arkhangai, Uwurkhangai, Selenge, Darkhan-Uul aimags ,Bulgan province and 59 strokes, 39 careers have been chosen by random sampling and involved in this research. For processing training curriculum usedSPICEST Model Medical Education, Healthy Learner Model, Model Neurology Progress – Oriented Triage by Likert and vivo quality discussion models are used in this research. To process statistics used IMB SPSS statistics and other 20 programs. The average students’ age who involved in this study was 20-22, nurses and special workers of thehospital was 23-2.3, and average age of stroked patients was 5Б2±3, 2, and average age careers 35±2. And occasion who had stroke after 62 (p<0,01) is increasing statistical important. Basic ordering had paralysis 84, 1%, and 84, 3%, patience had neurological originated , hypertension in 91%,,,trouble because of fear is 73,2%, polakuira had in 23%, person who had tongue problem in 36%. For patients who had strokes family members take cares for 30(50, 84%), nurses 21(35, 59%), and volunteers 6(10,16%) and most important things for them were wheelchair and walking cane. 41(69,4%) considered that it is very important nursing care for stroked patients. 72(34%) of graduatesconsidered that it is very important nursing care for stroked patients and 38(18,09%) considered important, also 58,3% estimated medium enough . For training curriculum of basic professions strokes contents to prepare professional nurses required 3-4 years or 108-146 credit hours and neurological nursing needs 0.8 credit hours and it takes 8-0.6 percent of total hours. For neurological nursing program involved nursing of common diseases, In the content of present training considered generally reflected about pulse diseases dis considered generally about the training content we cannot consider special difference between them.In branch school of medical sciences implemented core program since 2010. In the frame of common neurological deceases provided same 0.8 credit hours. In the content of host graduate training is not focused about neurological nursing care. It means that we take care less attention about content on issue of brain stroke, in other hand we have these specialists who are prepared by this directions.The main form of teaching is lecture and seminar. These forms are disresultative to own the forms of skills. But for the practice of cases and analyze on cases and provide discussions and writing essay about the analyze , and using training contents such as methods of training participation and independent works of available to use for in this case.

Objective: The purpose of this study was to establish oral health status among disabled children aged 6-12 years in 6 special schools in Ulaanbaatar. Methods: 428 children with disabilities (cerebral palsy, Down syndrome, mental retardation, blind and hearing disorders) participated in this study. Boys were 50.4%, girls were 49.6% and mean age were 9.921.76. Clinical examination was performed by using a dental mirror and revealed the presence of dental caries, missing (extracted) and fi lled teeth. Each tooth was examined and scored based on the WHO standard (WHO, 1997). The periodontal status was evaluated according to CPI (Community Periodontal Index). The oral hygiene was evaluated according to Green-Vermillion method (1964) values. Results: The dental caries prevalence of all disabled children was 88.3% and average dmft values were 5.714.54 in deciduous teeth, 5.733.72 in mixed dentition and 3.142.81 in permanent teeth. The periodontal status of all children was 70% bleeding after probing and 7% calculus deposit. The oral hygiene was 10% good, 37% fair and 53% poor. Conclusion: This study showed high caries prevalence and DMFT, dmft index and periodontal disease. The oral hygiene index was poor among disabled children in Ulaanbaatar comparing to general population. The main component of DMFT and dmft was decayed teeth, which suggest special oral health promotion policy and urgent treatment, diagnosis and special dental care.

BACKGROUND: Bladder cancer is a cancer of significant morbidity and mortality in the worldwide. It is the second most common urological cancer in Mongolia. It is important to understand the risk factors of bladder cancer.We evaluated the association of smoking, alcohol intake, body mass index and other potential risk factors with bladder cancer incidence in Mongolians.MATERIALS AND METHODS: We analyzed data from a case-control study (116 histologically confirmed bladder cancer cases and 300 cancer-free healthy, age, gender-matched controls). All participants signed the consent form andfilled out the structured questionnaire including cigarette smoking, BMI, chronic urinary disease andalcohol drinking etc. Using logistic regression we estimated the covariate-adjusted odds ratio (OR) and95% confidence interval (CI) of the associations.RESULTS: Mean age of the patients with bladder cancer was 56±10.5 years and 79.3% male and 20.7% female.Cigarette smoking, history of urinary tract diseases and body mass index were associated with an increased risk of bladder cancer OR 6, 48 (95% CI 1, 61-1, 70), OR 80 (95% CI 1, 48-1, 93) and OR=9.8 (95% CI 2.32-2.91) respectively but not alcohol drinking OR 0, 26 (95% CI 1, 56-1, 66).CONCLUSIONS: The results suggest that cigarette smoking, history of urinary tract diseases and body mass indexincreased risk of bladder cancer in Mongolian patients.

IntroductionThe p53 gene is frequently mutated in various forms of human cancers. The p53 signaling pathway isactivated by endogenous and exogenous stress signals and induces growth arrest, cellular senescenceand apoptosis. A common polymorphism occurs at codon 72 of the p53 has been demonstrated that itmight be associated with bladder cancer risk. However, results of researches related to this topic werecontroversial and more investigations and samples size needed.GoalTo evaluate TP53 Arg72Pro polymorphism in Mongolian patients with bladder cancer.Materials and MethodWe evaluated TP53 Arg72Pro polymorphism in DNA samples from 82 patients with bladder cancerand 82 age and gender matched healthy subjects using polymerase chain reaction-based restrictionfragment length polymorphism. All enrolments of this study were Mongolians. The association betweeneach genotype of TP53 Arg72Pro and bladder cancer risk was examined by the odds ratio and 95%confi dence interval, using logistic regression analysis. The early age onset of bladder cancer patientswas also evaluated among different genotypes of TP53 Arg72Pro.ResultsThe proportion of the polymorphism of TP53 Arg72Pro were RR 53.7% (n=44); PR 34.1% (n=28); andPP 12.2% (n=10) in the bladder cancer patients, whereas RR 52.4% (n=43); PR 28% (n=23); and PP19.6% (n=16) in healthy controls. The PR genotype increased the risk of bladder cancer (OR1.189;95% CI 0.42-0.75; p=0.997) in Mongolian people, whereas PP genotype protected from the cancer(OR=0.610; 95% CI 0.22-0.44, p=0.998) compared to the RR, respectively, however signifi cance isweak. Moreover, there was no association between each genotype of TP53 Arg72Pro (RR=52; PR=54;PP=58) and early onset of bladder cancer in the Mongolian population.Conclusion: Our result indicates that the PR genotype tends to increase the risk of bladder canceramong Mongolians. RR genotype of TP53 Arg72Pro is more prevalent among Mongolians.

BACKGROUND:The mouse double minute 2 (MDM2) is a negative regulator of the p53 tumor suppressor protein.Overexpression of MDM2 is associated with poor survival and is a useful predictive factor for poor prognosisin various cancers in human. Studies revealed a genetic polymorphism located in intron 1 of the MDM2gene, MDM2-SNP309, (a change from T to G) is main functional polymorphism and important to developtumors. However, inconsistent associations between the MDM2-SNP309 and the risk or early onset ageof human different cancers have been reported worldwide. These conflicting results may have dependedon different patient subgroups and ethnicities studies. We studied the association of the MDM2-SNP309polymorphism andbladder cancer in Mongolian patients for the first time.OBJECTIVE:To investigate association between MDM2-SNP309 and the risk bladder cancer or early onset age of thecancer in Mongolian patients.MATERIALS AND METHODS:We genotyped MDM2-SNP309 in 44 patients with bladder cancer and 44 age and gender matched healthycontrols among Mongolian people.Genomic DNA was extracted from whole blood samples by the standardmethod of Qiagen mini blood DNA extraction kit (Qiagen Inc., Valencia, CA) and PCR amplification wasperformed using 100 ng genomic DNA template according to manufacturer’s protocol (Invitrogen, Carlsbad,CA). MDM2 SNP309 genotyping was carried out by restriction fragment length polymorphism assay.RESULTS: The allele frequencies of MDM2 SNP309 in the 44 bladder cancer patients were wild-type (T/T) 27.3%,homozygous (G/G) 34.1% and heterozygous (T/G) 38.6% whereas in the control cases were wild-type(T/T) 29.5%, homozygous (G/G) 20.5% and heterozygous (T/G) 50.0%. The proportion of homozygous(G/G) genotype was higher for bladder cancer cases than for healthy controls. Compared to the low-risk(wild type) genotype, an increased risk association with bladder cancer was shown for the GG genotype(OR=2.0, 95% CI=1.03-1.84). There is also a significant difference in median age onset of bladder cancerbetween GG low and high risk genotypes T/T and T/G (p=0,003)( p=0.0001), respectively (Figure2).CONCLUTION: The current sample data suggests that MDM2 SNP309 GG genotype may be associated withthe risk of bladder cancer as well as an earlier age onset in Mongolian patients with bladder cancer.

BACKGROUND. Chronic rhino-sinusitis (CRS) is a common inflammatory disease of the nose and paranasal sinuses, especially after virus infections. It has a significant impact on patients’ quality of life. We aimed to evaluate the clinical value of low-level laser therapy (LLLT) forpediatric chronic rhino-sinusitis. METHODS. 30 patients 6-15 years old with CRS were divided into two groups: T1 were treated twice a week and T2 were treated five times a week for 2 treatment sessions within 2 weeks. Laser irradiation was delivered on 12 points over each maxillary and frontal sinuses with 30 seconds and the total treatment duration was 180 seconds. The evaluation was performed by a total symptom score based on SNOT-22 questionnaires of pre and after treatments. RESULTS. The total symptom scoreimproved significantly (p<0.15) in 27 cases. CONCLUSION. This study indicates that LLLT applied for 4 weeks improves symptoms in patients with CRS. LLLT is one of the most cost-efficient and painless treatment methods for pediatric rhino-sinusitis.