1. Determination of Toxocara canis infection in patients with Idiopathic Chronic Urticaria
Nyamdari A ; Altanzul KH ; Gurbadam A
Innovation 2014;8(2):20-23
Urticaria affects 15–25% of the population once in their lifetime. Also 0.5-1% of the population suffers from the idiopathic chronic urticaria. More than 80% of chronic urticaria is idiopathic. 24% of the world’s population are infected with soil-transmitted helminth infections worldwide. Toxocara canis is associated with urticaria. To determine T.canis IgG antibody in patients with idiopathic chronic urticaria. Materials and methods: The study was a case-control study. There were enrolled 40 patientswith confirmed diagnosis of idiopathic chronic urticaria (ICU) at National Dermatology Center and 60 controls without any skin diseases between the ages 12-64 years. Blood samples were tested using an enzyme linked immunosorbent assay (ELISA) technique for the detection of IgG specific antibodies to T.canis excretory-secretory (TES) antigens (Ridascreen® toxocara IgG).15% of urticaria patients were male, 85% were female and the mean age was 34,50±14,36. 18.3% of healthy control groups were male, 81.7% were female and the mean age was 39,77±11,24. 32.5% (13/40) of patients presenting with ICU had positive results to TES-ELISA. About control group: 5% (3/60) were positive TES-ELISA serology result. The pet-keeping history gave the following results: 48% of urticaria patients and 55% of control patients were in possession of dog; this difference was no significant (p>0.1). Our data show that T.canis is one of the etiologic factor in patients with ICU (p=0.001, OR (95% CI)=9.148 (2.404-34.808). The analysis of risk factors evidenced that the presence of dogs within the houses and household location showed no significant association with T.canis infection (p>0.1).
2. ASSESSMENT OF ORAL HYGIENE OF DEPRESSIVE DISORDER PEOPLE
Jargal B ; Delgermaa J ; Khishigsuren Z ; Altanzul N ; Altanzul B ; Erdenesuvd N ; Bilegsaikhan P ; Altanchimeg KH ; Nyamsuren M
Innovation 2015;9(1):38-40
The oral hygiene is not relatively good cause of smoking, ignoring oral hygiene, not having enough self-care skills and independent living in case mental illness. Their grinding the teeth, serotonin decreases when the people are depressed and then it makes the carbohydrates increases, loses the sense of taste. Therefore they use a lot of sweet, the salivary output decreases, increase in the number of lactobacili and then it makes the cause ofabnormal disease detections including tooth decay, trigeminus neural pain in temporomandibular joint /TMJ/, oral yeast infection, oral bad breath, burning sensation of the tongue, chronic facial pain. Also the oral can disease detects from drug causes like using the anti-depression drugs for at least 6 months.Using analytical research permanent design, I got 55 patients to take part in the survey who are staying in 5th flat , National Clinic of Mental Health from 22nd of September 2014 until 26th of September. When I do the research for history of their patients: among the diagnosis of 16 people disorder depressed, the 13 patients agreed to have a preventive examination voluntary, one of them declined to do it. I use many methods of researching like questionnaire methods interview method, prevention oforal cavity and clinical examinations, respectively Study shows that curriculum contents of School of Nursing, Mongolian National University of Medical Sciences have comparatively less contents of understanding about healthy person, assessment on human, giving advice healthy human, path anatomy, physiology, communication skills.The most of the survey participant patients have holes in their teeth, gum inflammation, and tongue stress disorder. It shows that it decreased to pay attention on their oral hygiene associated with symptoms and it effects directly related to the decrease in salivary output.Depressed People are so bad at paying attention to their oral hygiene habits.
3.Identifying relation of anxiety and salivary cortisol among abused children
Altanzul Kh ; Munkhtulga G ; Tsend-Ayush A ; Oyunbileg O ; Jargal B ; Odkhuu E ; Khishigsuren Z
Innovation 2013;7(2):44-48
WHO informed that across world an average of 565 young people aged 10 to 29 die every day through interpersonal violence. Some studies mentioned that anxiety was most frequently occurred as one of the psychological consequences among victims of child abuse. Recent research on effects of adverse early life experiences on central nervous system as stress systems (hypothalamus-pituitary-adrenal axis-HPA) has provided a greater understanding of the link between childhood abuse and susceptibility to anxiety disorder. Therefore, this research was done to study anxiety among abused adolescents, some physical parameters and level of cortisol in saliva.
There were selected 20 abused children and 40 non abused children aged between 11-16 years old and lived in Ulaanbaatar city. The Spence Children’s Anxiety Scale (SCAS; Spence, 1997) is a 38-item self-report questionnaire that assesses multiple symptoms of childhood anxiety disorders based on current diagnostic criteria. All participants were measured the cortisol in the saliva by Cortisol ELISA kit, Sigma,
Average age of all subjects in the study was 13.52±1.57 and 59% of them were female and 41% were male. All anxiety symptoms of case group was statistically significance higher (p<0.01) than control group. The average amount of salivary cortisol of case group was (18.65±7.08) statistically significantly lower (p<0.01) than average amount of control group (32.15±20.99).
Anxiety was more frequently occurred among abused children and blunted cortisol responses might indicate a level of impaired HPA functioning that could constitute a vulnerability to psychopathology with exposure to anxiety.
4. Identifying relation of anxiety and salivary cortisol among abused children
Altanzul KH ; Munkhtulga G ; Tsend-Ayush A ; Oyunbileg O ; Jargal B ; Odkhuu E ; Khishigsuren Z
Innovation 2013;7(2):44-48
WHO informed that across world an average of 565 young people aged 10 to 29 die every day through interpersonal violence. Some studies mentioned that anxiety was most frequently occurred as one of the psychological consequences among victims of child abuse. Recent research on effects of adverse early life experiences on central nervous system as stress systems (hypothalamus-pituitary-adrenal axis-HPA) has provided a greater understanding of the link between childhood abuse and susceptibility to anxiety disorder. Therefore, this research was done to study anxiety among abused adolescents, some physical parameters and level of cortisol in saliva.There were selected 20 abused children and 40 non abused children aged between 11-16 years old and lived in Ulaanbaatar city. The Spence Children’s Anxiety Scale (SCAS; Spence, 1997) is a 38-item self-report questionnaire that assesses multiple symptoms of childhood anxiety disorders based on current diagnostic criteria. All participants were measured the cortisol in the saliva by Cortisol ELISA kit, Sigma, Average age of all subjects in the study was 13.52±1.57 and 59% of them were female and 41% were male. All anxiety symptoms of case group was statistically significance higher (p<0.01) than control group. The average amount of salivary cortisol of case group was (18.65±7.08) statistically significantly lower (p<0.01) than average amount of control group (32.15±20.99).Anxiety was more frequently occurred among abused children and blunted cortisol responses might indicate a level of impaired HPA functioning that could constitute a vulnerability to psychopathology with exposure to anxiety.