1.Electrochemiluminescence Behavior of Luminol at Closed Bipolar Electrode and Its Analytical Application
Chinese Journal of Analytical Chemistry 2014;(8):1221-1224
A new closed bipolar electrode electrochemiluminescence ( ECL)-based device was designed, and further used to investigate the ECL behaviors of luminol in this device. Our results showed that, while a suitable voltage was applied to the two poles of the closed bipolar electrode, both the positively charged ions and luminol-based anionic ions could be enriched on the two poles of the closed bipolar electrode, respectively. More importantly, the ECL signals, generated from the electro-oxidation of luminol on anodic pole, were found to be related to the total amount of positively charged ions on the cathodic pole of the closed bipolar electrode. Under the optimum experimental conditions, the ECL response was linearly to the concentration of analyte in the range of 1. 0×10-9-1. 0×10-8 mol/L with a detecting limit of 1. 1×10-10 mol/L. Based on this finding, a new ECL method for sensing the solution conductance was developed.
2.Study on Effects of Compound Rhizoma Bletillae Paint on Burning and Blanching Wound in Rats
Liming HUANG ; Chengrong SUN ; Along KANG
Chinese Journal of Information on Traditional Chinese Medicine 2008;0(S1):-
Objective To study the effects of compound rhizoma bletillae paint (CRBP) on scalded rats. Methods Rats were randomly divided into test groups (CRBP low, high dose group), CRBP-CA (CRBP without chlorhexidine acetate) group, positive control group (Jingwanhong) and negative control group (no treatment) respectively, with 10 rats in each group. The drugs were administered topically on the surface of scalded places respectively after second-degree and third-degree burn scald models in rats. The rats were bred separately. The scabbing time, decrustation time and wound healing time were recorded. Results The scabbed and the decrustation time were shorter in the test group than that in the negative control group with significant differences (P
3.Quality Standard of Baoshenling Capsules
Chengrong SUN ; Xian ZHANG ; Along KANG ; Shutong LI ; Suocheng ZHANG ; Chao GUO
China Pharmacy 2001;0(12):-
OBJECTIVE:To establish the quality standard of Baoshenling capsules.METHODS:Radix Astragali,Radix et Rhizoma Rhei,Ligusticum chuanxiong and Hirudo were identified qualitatively by TLC,and the content of diphenyl ethylene in Baoshenling capsules was determined by HPLC.RESULTS:The characteristic TLC spots of Radix Astragali,Radix et Rhizoma Rhei,Ligusticum chuanxiong and Hirudo were identified accurately.The linear range of diphenyl ethylene was 0.176~0.880?g(r = 0.999 8) with an average recovery rate of 98.9%(RSD = 1.3%,n =6).CONCLUSION:The established standard is applicable for the quality control of Baoshenling capsules.
4.Correction of enhanced dynamic wedge factor and analysis of monitor unit calculation.
Sijuan HUANG ; Lixin CHEN ; Wufei CAO ; Wenzhao SUN ; Along CHEN ; Bojio LIU ; Bin WANG
Journal of Southern Medical University 2015;35(2):260-263
OBJECTIVETo study the correction of algorithm for Varian enhanced dynamic wedge(EDW) factors and compare the dose/monitor unit (MU) deviation measured at the central axis of EDW field with that obtained by manual calculation or using the treatment planning system.
METHODSEDW factors and dose were measured with Thimble ion chamber at 10 cm depth under the water for 6 MV and 10 MV photon on Varian linear accelerator. The corresponding calculations were done with the radiation treatment planning system. An analytic formula, namely the MU Fraction model, was used to calculate the EDW factor, which was corrected with a constant factor. The MU of conventional 2-D planning derived from manual calculating, treatment planning system, and actual measurements were compared.
RESULTSWith the measured results as the standard, the corrected manual calculation deviation of EDW factors was significantly reduced. For photon 6 MV, the maximum deviation reduced from 4.2% to 1.3% for 60° symmetry fields was, and from -4.7% to -1.8% for asymmetric fields. For photon 10 MV, the maximum deviation for all EDW fields was reduced from -3.0% to 1.1%. Comparison of the manual calculations with the measured results showed a MU deviation for symmetric fields within 2%, and more than 5% for some asymmetric fields. The deviation between the calculations of the treatment planning and the measured results was less than 1.5%.
CONCLUSIONConstant factor correction can effectively reduce the deviation of manual calculation. For MU calculation of EDW field in conventional 2-D dimensional treatment planning, the corrected results of symmetric fields meet clinical requirements. While the minimum distance between the field edge and the central axis was less than 4 cm in asymmetric fields, the corresponding special method, measurement or the treatment planning system should be used to calculate the dose/MU.
Algorithms ; Models, Theoretical ; Particle Accelerators ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted