1.Metabolic alkalosis induced by plasmapheresis in a patient with systemic lupus erythematosus.
Moon Young CHOI ; Joung Deuk LEE ; Seung Hun LEE ; In Seok PARK ; Je Young WOO ; Euy Jin CHOI ; Yoon Sik CHANG ; Byung Kee BANG
Journal of Korean Medical Science 1993;8(3):207-209
We report a patient with systemic lupus erythematosus (SLE), who had developed metabolic alkalosis during plasmapheresis. The metabolic alkalosis could be promptly corrected by reducing the amount of citrate load. The development of metabolic alkalosis can be explained by the citrate load during plasmapheresis. Careful monitoring of acid base status is mandatory in patients with limited renal function and the reduction of citrate load may be advisable in plasmapheresis.
Adolescent
;
Alkalosis/*etiology
;
Citrates
;
Citric Acid
;
Female
;
Humans
;
Lupus Erythematosus, Systemic/*metabolism/therapy
;
Plasmapheresis/*adverse effects/methods
2.Liddle's syndrome: a report in a middle-aged woman.
Yonsei Medical Journal 2000;41(2):276-280
A 54-year-old woman with diabetes mellitus was hospitalized with generalized edema and weakness. She was also found to have hypertension, hypokalemia and metabolic alkalosis. Detailed examination showed subnormal plasma renin activity and plasma aldosterone concentration. Adrenal CT scanning revealed no adrenal tumor. A successful treatment with amiloride established the diagnosis of Liddle's syndrome for the patient. Liddle's syndrome, a rare hereditary disease usually found in young patients, should be considered in the differential diagnosis of hypertension even in elderly individuals.
Aldosterone/deficiency*
;
Aldosterone/blood
;
Alkalosis/genetics*
;
Case Report
;
Female
;
Human
;
Hypertension/etiology
;
Hypokalemia/genetics*
;
Middle Age
;
Renin/deficiency*
;
Renin/blood
;
Syndrome