INTRODUCTION:Alcohol (EtOH) use disorders (AUDs) represent a substantial public health problem worldwide. Over 76million people present with AUDs 2.5 million deaths were attributed to alcohol (World Health Organization,2010). Channadshelshi has been used for treatment of alcohol-related, liver disease and intoxication intraditional medicine.GOAL:To determine effect of channadshelshi on voluntary alcoholic wistar rats.MATERIALS AND METHODS:To examine acute toxicity of Channadselshi were used V.P.Prozorovsky express method (1978) andOECD (2001).Voluntary EtoH consumption measurement (two-bottle choice, intermittent access to EtOH paradigm inwistar rats). Water and 20% ethanol were presented in 200 mlgraduated plastic cylinders with stainlesssteeldrinking spouts.The experiment period was 10 weeks total. EtOH consumption was expressed asgrams of EtOH consumed per kilogram of body weight/day.Elevated plus maze. Anxiety associated with EtoH withdrawalwas measured on EPM The mazewaselevated 1 m above the floor and contained four 50 cm long, 10 cmwidearms arranged at rightangles. The closed arms had opaque walls 30cm high, extending the length of the arm. At the time of thetest, eachanimal was placed in the center of the maze facing an open arm andallowed to explore for a5 min session. During this 5 min test session, theanimal’s number of arm entries and time spent in eacharm per entry was recorded on a camera.Pentylenetetrazol (PTZ) 100 mg/kg dose used in this study was determined as the dose that inducedseizures and protection against mortality in miceThe experimental protocol was approved by the Ethics Committee of the MNUMS. (№ 14-11/1À)RESULTS:LD50 of Channadselshi extract was found to be LD50=2.58 (2.1-3.2) gr/kg by V.P.Prozorovsky expressmethod (1978). Channadselshi was no acute toxic by OECD (2001).Ten and four weeks oral administration of Channadselshi (200 mg/kg) significantly (P<0.01) decreasedthe consumption of ethanol and significantly (P<0.01) increased time spent in open arm (EPM) involuntary alcoholic wistar rat compare to control.The time (sec) of latency the generalized convulsion were significantly (P<0.01) increased ofChannadselshi compare to control. The percent of protection against mortality were 80% in PTZinduced seizure in mice.CONCLUSIONS:1. Our study showed that Channadselshi hasreduced consumption of ethanol in voluntary alcoholicwistar rat.2. Channadselshi has central nervous system protection effect against PTZ induced seizure in mice.

Children with impaired hearing have communication and learning difficulty due to delay in the development of receptive and expression communications. Communication difficulties can often lead to social isolation and poor self-estimation. Oral health status in children with impaired hearing tends to be poor due to several reasons as difficulty of adequate training of caregiving parents, parents luck of information and effort. Aim: To study oral health status and oral education level among students of special school №29 for disabled children.A cross-sectional descriptive study. 224 students aged 6-22 years were selected for this study. Participants were subjected to oral examination and were asked to answer to the questionnairePrevalence of caries and DMFT index, dental plague, occlusion and the oral education levels were assessed. The caries prevalence was 95.9%, and the mean DMFT index was 5.5. Dental plaques were identified in 31.7-49.2% of subjects differing among age groups. Among examined children, 32% of subjects had a malocclusion and 18 children underwent cleft lip palate surgical treatment. According to questionnaire 21% of subjects reported that tooth brushing is not significant measure to maintain oral health, which shows that oral education level among subjects was low. Oral health status of children with impaired hearing was in a level comparable to that of healthy children, although the incidence of cleft lip and palate and gingivitis were higher.

Aim: To study the beneficial effects of Jamts-4 tan in an experimental pancreatitis model. Methos: Acute pancreatitis was induced in four groups of rats (n = 10) by L-arginine 20% solution (450 mg x100g, intraperitoneal single injected) and 3 days later, they received a single oral dose of Jamts-4 tan (140 mg/kg), Pancreatin (100 mg/kg) and vehicle (distilled water). A saline (0.9% NaCl) treated group served as a normal control. Efficacy was assessed determination of serum levels of amylase, glucose. Results: Jamts-4 tan treatments significantly (P < 0.009) attenuated the L-arginine-induced increases in pancreatic wet weight/body weight ratio, and decreased the serum levels of amylase as compared to the vehicle control. Conclusion: Jamts-4 tan has the potential to combat acute pancreatitis

Objectives: To investigate of Lonal praparation for antidiabetic effects in diabetic rats induced by alloxan. Methods: Diabetic animals were randomly divided into 3 groups and treated orally with different doses (100 mg/kg body weight) Lonal extract once a day for 21 days. The body weight of each animal was determined, to assess any possible weight gain or loss in experimental animals compared with control groups. On the 21st day, those administered 100 mg/kg of Lonal showed more promising results with regard to fasting blood glucose (FBG), water intake when compared to those treated with other doses. Therefore, 100 mg/kg dose was used for further biochemical studies. Total cholesterol (TC), triglycerides (TG), Alat, Asat, ALP, low density lipoproteins (LDL) and high density lipoproteins (HDL) levels, on normal and diabetic rats treated with the dose of 100 mg/kg, were evaluated. Results: The flower extract shows a significant (p

Introduction: There is an increasing need to study traditional medical sourcebooks and explanatory materials to enrich and develop medical concepts and clinical practices. Objectives: To study Mongolians contribution of nomenclature, origin andclassification of precious medicine using traditional medical sourcebooks and explanatory materials. Results and conclusion: The sourcebook “The Four Medical Tantras”written 10 type of jewel and the sourcebook “Em tanikh ukhaan”hadreferred mentioned above brass and plumbum. Although, this book determined jewel medicines shape, function and treatment, how to know these jewel.In the sourcebook “Uzesgelent nuden chimeg” jewel had divided an not fluxible-25, fluxible-13. These scientists medicinal prescriptions knowledge were shown greatly consideration in Mongolian traditional medicine.

Foreword: There is a demand to compare traditional medicine with modern medical science so that it will educate public for proper usage of natural traditional medicine such as main concept, identifying medical plants, reducing its volume, taste etc...1We mainly concentrated on comparisement of Mongolian religious healers books and chose following books for our research work that are “Thefour basic medicine” by Yutig Yondongombo Tibeten doctor and 2 other books by Mongolian doctor Luvsanchultem and Jambaldorj. Methods we used are analyzing, summarizing, comparing and classifying. According to a book “The four basic medicine” the animal starch includes horn, bone, meat, blood, gall, fat, brain, skin, nail, hair, urine, litter and body. Also, the book states their potential healing power. In a book named “Beautification” it says there are11 medicine comes from human and 124 medicine comes from animals and detailed classification is stated here. “Medicine identifying science” by Luvsanchultem Tsakhar gevsh (monastic title for a learned lama) says that there are 54 animal starch medicineand it shows us how to be aware of recognition and not to be mistaken. Here popular medicine are determined how to find out that is in good or bad condition, so that made it easier for us to identify and contributed greatly to Mongolian medical science.

Background: In traditional Mongolian medicine, ischemic heart disease are treated by balancing the body, promoting the flow of khii and blood, improving the metabolism, suppressing inflammation, increasing heart strength, relieving pain, and treating the disease according to its actual condition. Therefore, a study was conducted to investigate the effects of traditional medicines Heart Agar-8 and Zandan-3 on ischemic heart disease. Aim: Studying the therapeutic effects of some traditional medicines used in the treatment of ischemic heart disease. Materials and Methods: Clinical trial was performed in an uncontrolled, single-centered, and open-study design. A total of 48 patients with ischemic heart disease who met the inclusion criteria participated in the study. The study was conducted by giving people 3 grams of Heart Agar-8 and 3 grams of Zandan-3 medicine, each once a day, for a total of 3 weeks. The results of the study were assessed before and after the study using the SAQ questionnaire, the chronic coronary syndromes (CCS) questionnaire, 6-minute walk test, and electrocardiogram. The research was conducted in accordance with the appropriate ethical approvals (No. 24-25/03-01), (No. 2024-077) and confirmed by an informed consent form. Clinical trial research results were processed using T-test, Paired T-test. Results: A total of 48 people diagnosed with ischemic heart disease (TMK00.2) were included in the study. The average age of the study participants was 53.94±1.69, with the youngest being 44 and the oldest being 60. Regarding the gender of the respondents, 15 (31.25%) were men and 33 (68.75%) were women. When comparing pre-treatment results with post-treatment results using the SAQ, there were improvements in mobility (p<0.000), chest stability (p<0.012), chest pain (p<0.000), treatment satisfaction (p<0.001), and quality of life assessment (p<0.000). When assessing chronic cor onary syndrome in people, 44 or 91.6% of the total number of people included in the study had a level II score before treatment, while 37 or 77.08% had a level I score after treatment, which was a statistically significant difference between the pre-treatment and post-treatment indicators (p<0.034). Cardiac function was assessed by the 6-minute walk test, which was 393.9±36.73 meters before treatment, or grade II, but improved to 456.83±48.6 meters after treatment, or grade I (p<0.000). Conclusions 1. People diagnosed with ischemic heart disease have shown statistically significant results when given the traditional medicine Heart Agar-8 and Zandan-3 in combination with clinical trials. 2. The study participants experienced statistically significant improvements in mobility, usual activities, pain, and depression, improved quality of life, and increased functional status in coronary heart disease.

Background: Medicines with unique healing methods and European medical treatments and services, which have been used around the world to this day, are now being used in a combined form in the healthcare services of many countries, and the possibility of integrating them is a widely discussed issue among researchers. It is noteworthy that no independent research has yet been published that has analyzed in detail how the influence of Chinese and other medical schools has been reflected in the development of Traditional Mongolian medicine. It is considered important to analyze this issue individually, in each direction, to clarify the historical process of how Traditional Mongolian medicine was formed today. Aim: Conduct research within specific codes in the works of Mongolian doctors to identify the presence of Chinese medical data, knowledge, and information. Materials and Methods: The research was conducted using a qualitative research method based on historical and source books. Our study employed content and thematic analysis, utilizing coding and the identification of recurring patterns in the source text. Results: The results of the coding study show that most of the data used from Chinese meicines falls under the code “infection”. In Sumbe Khamba Ishbaljir’s sourcebook, 42.8% of the information was coded as infection, in Tsakhar Gevsh Luvsanchultemi’s sourcebook 50%, in Mindol Khutagt Jambalchoyjidanzanperenle’s sourcebook 47.05%, and in Ishdanzanvanjil’s “Shuren Chimeg” 87.5% was coded as infection. After that, when the information included in the code “injury” is classified by each sourcebooks, 33.3% is found in Ishbaljir’s sourcebook, 0% in Luvsanchultem, 24% in Min dol Khutagt Jambalchoyjidanzanperenley, and 6.25% in Ishdanzanvanjil, which ranks second among all codes. Conclusion 1. According to the research results, 56.66% of the Chinese medical information in the above works is related to infection cases. 2. The integration of Chinese medicine learning with Traditional Mongolian medicine methods during epidemics such as “Bodoo” may be a major influencing factor that has shaped the current integrative medicine process.

Background: When the incidence of the chronic shoulder pain syndrome is increasing year by year, it is necessary to determine the effects of pain relief, recovery of joint disability, and impact on quality of life through clinical trial research when calculating the results of Turem treatment, which is one of the main methods of traditional medical treatment. Aim: To study the effects of traditional medicine chiropractic on pain relief, mobility improvement, joint function recovery, and quality of life in chronic shoulder pain syndrome. Materials and Methods: The study was conducted using a single-blind, randomized controlled clinical trial (RCT) design. In the study, 60 clients were randomly selected from people suffering from of the shoulder joint pain, and group 1 received Turem treatment together with physical therapy, and group 2 received physical therapy. The results of the study were evaluated by shoulder pain (VAS score), muscle strength, range of motion of the shoulder joint with a goniometer, and the Disability of Arms, Shoulders, and Paws Questionnaire (DASH). The research was conducted in accordance with the appropriate ethical approvals (No. 2024/3-05), (No. 2024-18) and confirmed by an informed consent form. Clinical trial research results were processed using T-test, Independent T-test, repeated ANOWA test. Results: The average age of the participants in the study was 56.13±7.13 years in the treatment group and 53.87±8.05 years in the control group, and 55% were male and 45% female. When shoulder joint pain was evaluated by VAS assessment, the values before and after treatment and after 1 month of treatment in the turem treatment group and the control group decreased statistically significantly (p=0.000). There was a statistical difference between the results of the 2 study groups. When assessing muscle strength, no statistically significant difference was observed between the results of the turem treatment and control groups. When measuring the amplitude of the shoulder joint in the subjects, the amplitude of shoulder extension, abduction, external rotation, and inward rotation increased after the treatment, and compared to the two groups, the index of the turem treatment group increased with statistical significance (p=0.000). When assessed by the Hand, Shoulder, and Hand Dysfunction Questionnaire (DASH), the score of the questionnaire decreased significantly (p=0.000) before, after, and after 1 month of treatment in the turem treatment group and the control group. Turem treatment has been shown to reduce the rate of shoulder disability and improve function in chronic shoulder pain syndrome. Conclusion: Turem treatment for chronic shoulder pain syndrome can reduce shoulder pain, increase joint range, and improve muscle strength. Also, turem treatment reduced the rate of shoulder disability and improved function. Conclusion Turem treatment for chronic shoulder pain syndrome can reduce shoulder pain, increase joint range, and improve muscle strength. Also, turem treatment reduced the rate of shoulder disability and improved function.

Introduction: Diet therapy is based on body constitution, disease conditions and seasonal influences in traditional medicine. Traditional principles of disease treatment and prevention with diet can be combined with conventional medical practices and may lead to a possibility of developing new treatment and preventive strategies. Objectives: To study the effects of interconnected factors of diet and season on some pathological changes of organ systems, we examined the effect of horse meat which has hot quality and goat meat which has cold quality on rat models of acute hepatitis induced by CCL4 and acute pulmonary edema induced by adrenalin hydrochloride in the spring and autumn. Materials and methods: CCL4 (200 mg/kg) was administered percutaneously to induce acute hepatitis in rats. Adrenalin hydrochloride (25 mg/kg) injected via the tail vein by slow injection to induce acute pulmonary edema in mice. Horse and goat meat were given for 14 days before the CCL4 and adrenalin hydrochloride administration. Renal activity was determined by measuring urine volume every 6 hours. Results: Results of our study show that goat meat which has cold quality is more effective in the autumn when a rise of bile element is occurred, and horse meat which has a cold quality is more effective in the autumn when phlegm element rises. Horse meat increased pulmonary surfactant stability coefficient by 54.73% in the autumn while it increased that by 69.66% in the spring. Decreased alveolar collapse and improved pulmonary surfactant stability by horse meat treatment support the concept of traditional medicine that diseases of the lungs, phlegm dominant organs are treated with diet, medicine, and behavior with warm and oily qualities. In the spring, urine excretion was increased in animals treated with goat meat which has cold and oily qualities. Conclusions: 1. The “spring + horse meat” and “autumn + goat meat” versions of treatments more effectively decrease cytolysis during acute hepatocellular necrosis in animals administered CCL4. 2. Compare to goat meat, horse meat has more effects to decrease alveolar collapse and pulmonary edema in mice model of pulmonary edema induced by adrenalin hydrochloride. 3. “Goat meat + spring” version of treatment decreases urine excretion in experimental animals.