OBJECTIVE: To investigate the clinical characteristics and surgical treatment of Hashimoto's disease complicated with thyroid cancer. METHODS: Clinical data of 54 patients with Hashimoto's disease complicated with thyroid cancer were retrospectively analyzed, including clinical characteristics, surgical treatment, and short-term effects. RESULTS: The rate of Hashimoto's disease complicated with thyroid cancer was 14.9%, 54 out of in 362 patients with Hashimoto's disease. All the 54 patients had surgical treatment in proper thyroid region, took euthyrox after the operation and had 6 month to 4 year followup. One patient had a local recurrence and 3 had lymph node metastasis in the neck, and these 4 patients had second operation on the thyroid gland. No death occurred. CONCLUSION Hashimoto's disease complicated with thyroid cancer has no typical symptoms.Combined examination of anti-thyroid antibodies test, color doppler imaging, CT detection, isotope scan and core/fine needle biopsy may provide accurate diagnosis. Proper surgical treatment is effective for Hashimoto's disease complicated with thyroid cancer.
Adult ; Aged ; Carcinoma, Papillary ; complications ; diagnosis ; surgery ; Female ; Hashimoto Disease ; complications ; diagnosis ; surgery ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Thyroid Neoplasms ; complications ; diagnosis ; surgery ; Young Adult