1.Assessment of agnique MMF killing effect on A. sundaicus in the shrimp farms of Ca Mau province
Journal of Malaria and parasite diseases Control 2004;0(3):56-56
Insecticidal effects of Agnique MMF were investigated in the coastal brackish water shrimp farms in the Tan Thuan commune, Dam Doi district of Ca Mau province in 2000. The investigations were made in terracotta jars and shrimp ponds with the surface area 30m2 and 1000m2 each. Agnique MMF was found to have a high and fast killing effect on larvae of An.sundaicus at all three testing doses of 0.3ml/m2, 0.4ml/m2 and 0.5ml/m2. Especially larvae at instars of III, IV and pupae. However, the insecticide produced a low effect on Culex sitiens killing larvae of IV ins tar and only retarding larvae of I, II, III instar. The residual effect of Agnique MMF was found to be 14 days in the terracotta jars and 6 days in the ponds. In the direct observations, Agnique MMF was found to have no negative effects on rearing shrimps
Fatty Alcohols
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Polyethylene Glycols
2.Experiences of treatment for Alopecia Areata by smearing HDM alcohol and Chloral salicilic solution
Journal of Practical Medicine 2005;515(7):59-61
35 patients with Alopecia Areata (18 females, 17 males) were treated at Military hospital N0 108 from March 2002 to March 2005, age from 4 to 58 years old. All patients were treated by HDM alcohol and Chloral salicylic solution 2% in 4 months. The results showed that: after first month of treatment, 77.14% of patients had grew hair root; after 2 months, there was only 8.57% of patients had not yet grew hair root. After 3 months, the rate of grew hair with different levels was 100%, among which 60% had normal grew hair, and after 4 months 82.86% of patients had grew hair as normally, 17.14% had grew hair from 2 cm. Side effects were observed in 10 patients (28.57%) involved erythema 8.57%, itch 14.29% and deciduous skin 5.71%.
Alopecia Areata
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Alcohols
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Therapeutics
3.Alcohol, beer and injury accident
Journal of Practical Medicine 2005;512(5):64-65
Retrospective epidemiology and documentary analysis collected from National Medical Investigation to evaluate an alcohol abuse situation and its harmful effect. The results: alcohol abuse is a social evil. It does not estimate and consider adequately from managers, experts and people so far. Alcohol abuse is important role in increasing injuries such as: traffic, violence, poison, suicide and sexual assault. It is necessary to have appropriate methods, sanctions for people, who drinks alcohol while driving and breaks the law
Accidents
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Wounds and Injuries
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Beer
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Alcohols
4.Some factors related to traffic accidents in motorcycled drivers who were admitted to ThaiNguyen general hospital in the year 199956
Journal of Practical Medicine 2004;481(6):56-58
145 motorists who experienced traffic accident were admitted to Thai Nguyen General Hospital. Investigation showed that: the peak hours at 12-16 hour and 18-21 hours, and the main victims were riding on large size motor. Accidents were mostly occurred in straight road, narrow and out-of-the way roads, crowded place with many primitive means of transport in the road. Motoris victim was usually tired, fully strained, feeling sleepy, with high blood concentration of alcohol and beer (37.2% - 48.9%). The most frequent trauma was at the face and neck areas, skull brain trauma.
Accidents, Traffic
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Epidemiology
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Blood
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Alcohols
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Beer
6.Prevalence of smoking and drinking habits among Form Six students in Petaling District, Selangor.
M Z Nor Afiah ; A R Hejar ; K C M Kulanthayan ; J Fadhilah ; T H Law
The Medical journal of Malaysia 2006;61(1):41-7
Smoking and alcohol intake patterns may persist from adolescence to adulthood. The aims of this study are to determine the prevalence and factors associated with smoking and drinking habits among Form Six students. This was a cross-sectional study conducted in January 2003 among Form Six students from government schools in the Petaling District, Selangor. A hundred and thirty six self-administered questionnaires were distributed to students selected through multistage stratified sampling. Response rate in this study was 90.1% (136/151). The respondents were mainly Chinese 60 (44.1%) and female 88 (64.7%). The prevalence of smoking was 22.8%, whereas the prevalence of alcohol intake was 47.8%. Only 33.1% of the respondents practiced undetermined activities and 1.5% have undetermined characters. There were significant associations between smoking and males (Adjusted OR 2.56, 95% CI 1.02-6.43) and smoking and alcohol intake (Adjusted OR 2.74, 95% CI 1.11-6.78). Alcohol intake has significant negative association with Malays (Adjusted OR 0.83, 95% CI 0.03-0.27). Smoking habits among adolescents were associated with males and alcohol intake. However, only alcohol intake was negatively associated with Malays. Program interventions to reduce behavioral problems, particularly smoking and alcohol intake should be emphasized.
Smoking
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Alcohols
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Manufactured form
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Six
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Cephalic index
7.Treatment of Chronic Isolated Finger Flexor Tenosynovitis Through 50% Dehydrated Alcohol Installation.
Jae Eun SHIN ; Jung Hyun PARK ; Ho Sung YI ; Byung Kook YE ; Hyoung Seop KIM
Annals of Rehabilitation Medicine 2013;37(4):586-590
The isolated idiopathic finger flexor tenosynovitis is a rare condition, related to diversed etiologies. The traditional treatment of flexor tenosynovitis includes medications and injection of steroids. If the conservative treatment is not effective, surgical management is usually recommended. And alcohol installations have been rarely performed. We are reporting an extremely rare case of a 56-year-old man who had chronic idiopathic isolated finger flexor tenosynovitis which was treated through alcohol injections. The patient had not yet been treated despite of medication and serial injections of steroid. We performed 1 mL of 50% ethanol injection for the initial treatment and the second injection was done in the same way 10 months later due to the improvements of the patient's clinical symptoms and images of the follow-up ultrasonography. As a result, the authors suggest alcohol installation as an alternative non-surgical treatment for flexor tenosynovitis when other conservative managements are not effective enough.
Alcohols
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Ethanol
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Fingers
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Follow-Up Studies
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Humans
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Steroids
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Tenosynovitis
8.Microbial green manufacturing of higher alcohols.
Xiaoyan MA ; Xueqin WANG ; Lianjie MA ; Yi-Xin HUO
Chinese Journal of Biotechnology 2021;37(5):1721-1736
Higher alcohols that contain more than two carbon atoms have better fuel properties than ethanol, making them important supplements and alternatives to fossil fuels. Using microbes to produce higher alcohols from renewable biomass can alleviate the current energy and environmental crises, and has become a major future direction for green biomanufacturing. Since natural microbes can only produce a few higher alcohols in small amounts, it is necessary to reconstruct the synthetic pathways for higher alcohols in model industrial strains through metabolic engineering and synthetic biology to overcome the metabolic bottlenecks. A series of milestones have been accomplished in past decades. The authors of this review have witnessed the entire journey of this field from its first success to the leaping development. On the 30th anniversary of the founding of the discipline of metabolic engineering, this review dates back to the great milestones in achieving heterologous production of higher alcohols in non-native strains. The design and optimization of high alcohol biosynthetic pathways, the expansion of feedstock, the engineering of host strains and the industrialization process are summarized. This review aims to draw further attention to microbial synthesis of higher alcohols, inspire the development of novel techniques and strategies of metabolic engineering, and promote the innovation and upgrade of China's biofuel industry.
Alcohols
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Biofuels
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Biosynthetic Pathways
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Ethanol
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Metabolic Engineering
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Synthetic Biology
9.Construction of multi-enzyme cascade reactions and its application in the synthesis of bifunctional chemicals.
Jumou LI ; Kun SHI ; Zhijun ZHANG ; Jianhe XU ; Huilei YU
Chinese Journal of Biotechnology 2023;39(6):2158-2189
The synthesis of fine chemicals using multi-enzyme cascade reactions is a recent hot research topic in the field of biocatalysis. The traditional chemical synthesis methods were replaced by constructing in vitro multi-enzyme cascades, then the green synthesis of a variety of bifunctional chemicals can be achieved. This article summarizes the construction strategies of different types of multi-enzyme cascade reactions and their characteristics. In addition, the general methods for recruiting enzymes used in cascade reactions, as well as the regeneration of coenzyme such as NAD(P)H or ATP and their application in multi-enzyme cascade reactions are summarized. Finally, we illustrate the application of multi-enzyme cascades in the synthesis of six bifunctional chemicals, including ω-amino fatty acids, alkyl lactams, α, ω-dicarboxylic acids, α, ω-diamines, α, ω-diols, and ω-amino alcohols.
Amino Acids
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Biocatalysis
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Amino Alcohols
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Coenzymes/metabolism*
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Diamines
10.Identification of critical process parameters of Jinqing alcohol precipitation of Reduning Injection by big data.
Hui DU ; Bing XU ; Fang-Fang XU ; Xin ZHANG ; Qing WANG ; Chun-Yan XIA ; Le-Wei BAO ; Zhen-Zhong WANG ; Yan-Jiang QIAO ; Wei XIAO
China Journal of Chinese Materia Medica 2020;45(2):233-241
Lonicerae Japonicae Flos and Artemisiae Annuae Herba(LA or Jinqing) alcohol precipitation has various process parameters and complex process mechanism, and is one of the key units for manufacturing Reduning Injection. In order to identify the critical process parameters(CPPs) affecting the weight of the extract produced from the alcohol precipitation process, 259 batches of historical production data from 2017 to 2018 were collected, with a total of 829 318 data points. These data showed characteristics of large data, such as a large data volume, a low value density, and diverse sources. The data cleaning and feature extraction were first performed, and 48 feature variables were selected. The original data points were reduced to 9 936. Then, a combination of Pearson correlation analysis and grey correlation analysis were used to screen out 15 potential critical process parameters(pCPPs). After that, the partial least squares(PLS) was used in prediction of the weight of the extract, proving that the performance of predictive model based on 15 pCMAs is equivalent to that of predictive model based on 48 feature variables. The variable importance in projection(VIP) index was used to identify 9 CPPs, including 2 alcohol precipitation supernatant volume parameters, 4 initial extract weight parameters and 3 added alcohol volume parameters. As a result, the number of data points was 1 863, accounting for 0.28% of the original data. The big data analysis approach from a holistic point of view can effectively increase the value density of the original data. The critical process parameters obtained can help to accurately describe the quality transfer mechanism of the Jinqing alcohol precipitation process.
Alcohols
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Big Data
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Drugs, Chinese Herbal/chemistry*
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Solvents
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Technology, Pharmaceutical