1.Bronchiectasis and COVID-19 infection: a two-way street
Grace OSCULLO ; Daniel Jose GÓMEZ-OLIVAS ; Thais BEAUPERTHUY ; Amina BEKKI ; Alberto GARCIA-ORTEGA ; Gabriella Maria MATERA ; Mario CAZZOLA ; Angel Miguel MARTINEZ-GARCIA
Chinese Medical Journal 2022;135(20):2398-2404
Bronchiectasis (BE) has been linked to past viral infections such as influenza, measles, or adenovirus. Two years ago, a new pandemic viral infection severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) broke out and it still persists today, and a significant proportion of surviving patients have radiological and clinical sequelae, including BE. Our aim was to thoroughly review the information available in the literature on the bidirectional relationship between SARS-CoV-2 infection and the development of BE, as well as the impact of this infection on patients already suffering from BE. Available information indicates that only a small percentage of patients in the acute phase of coronavirus disease 2019 (COVID-19) pneumonia develop BE, although the latter is recognized as one of the radiological sequelae of COVID-19 pneumonia, especially when it is caused by traction. The severity of the initial pneumonia is the main risk factor for the development of future BE, but during the COVID-19 pandemic, exacerbations in BE patients were reduced by approximately 50%. Finally, the impact of BE on the prognosis of patients with COVID-19 pneumonia is not yet known.
2.Operative Technique for En Bloc Resection of Upper Cervical Chordomas: Extended Transoral Transmandibular Approach and Multilevel Reconstruction.
Luis Alberto ORTEGA-PORCAYO ; Eibar Ernesto CABRERA-ALDANA ; Nicasio ARRIADA-MENDICOA ; Juan Luis GOMEZ-AMADOR ; Martin GRANADOS-GARCIA ; Juan BARGES-COLL
Asian Spine Journal 2014;8(6):820-826
Anterior exposure for cervical chordomas remains challenging because of the anatomical complexities and the restoration of the dimensional balance of the atlanto-axial region. In this report, we describe and analyze the transmandibular transoral approach and multilevel spinal reconstruction for upper cervical chordomas. We report two cases of cervical chordomas (C2 and C2-C4) that were treated by marginal en bloc resection with a transmandibular approach and anterior-posterior multilevel spinal reconstruction/fixation. Both patients showed clinical improvement. Postoperative imaging was negative for any residual tumor and revealed adequate reconstruction and stabilization. Marginal resection requires more extensive exposure to allow the surgeon access to the entire pathology, as an inadequate tumor margin is the main factor that negatively affects the prognosis. Anterior and posterior reconstruction provides a rigid reconstruction that protects the medulla and decreases axial pain by properly stabilizing the cervical spine.
Chordoma*
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Humans
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Neoplasm, Residual
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Pathology
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Prognosis
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Spinal Neoplasms
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Spine