The study was conducted in Khanh Trung commune, Khanh Vinh district of Khanh Hoa province to assess the mosquito infection two years after DEC administration. Seventeen species of mosquito belonging to 5 genera have been found of which the main vector Wuchereria bancrofti was predominant. Indoor collection of Culex quinquefasdatus at daytime and nighttime was 3.5 and 2.3 individuals/house, respectively. Cx. vishnui was mainly found on the cattle sheds with an average density of 4.6 individuals/shed. A total of 578 mosquitoes of five species (Cx. quinqllefasciatus, An. vaglls, Cx. tritaeniorhynchus, Cx. vislznui, Cx. fuscocephalus) were dissected. None of them were positive with microfilaria.
Culicidae ; Albendazole

The authors had performed stereotactic surgery to diagnose and treat 2 cases of neurocysticercosis under the local anethesia. Generally, such the open surgery need a general anethesia which may increase the chance of brain parenchyml injury. However, the stereotactic surgery has the advantage of being an easy and precise procedure under local anethesia. The authors reviewed the literature and discussed the stereotactic surgery in the diagnosis, and treatment of neurocysticercosis.
Albendazole ; Brain ; Diagnosis ; Neurocysticercosis* ; Praziquantel

An oculogyric crisis which was resolved after intravenous injection of diazepam 10 mg developed in a 16-year-old girl after an oral dose of 400 mg of albendazole. Although ocular side effects of albendazole are rare, it can induce an alarming oculogyric crisis in some sensitive subjects. The mechanism of the oculogyric crisis is unclear.
Adolescent ; Albendazole* ; Diazepam ; Female ; Humans ; Injections, Intravenous

Toxocariasis has a broad clinical spectrum, from asymptomatic to systemic illness. However, cerebral toxocariasis has rarely been reported. We experienced a patient who presented with seizure and memory disturbance after treatment for visceral larva migrans of toxocariasis. Laboratory findings included eosinophilia, cerebrospinal fluid (CSF) pleocytosis, and positive results for toxocariasis in the serum and CSF. The patient showed marked improvement after combined albendazole and steroid treatment. This case indicates that cerebral toxocariasis is an unusual cause of cognitive dysfunction and seizure.
Albendazole ; Eosinophilia ; Humans ; Larva Migrans, Visceral ; Leukocytosis ; Memory ; Seizures ; Toxocariasis

Albendazole ; adverse effects ; Child, Preschool ; Drug Eruptions ; etiology ; Humans ; Tablets

PURPOSE: The aim of this study was to evaluate long-term outcome of the intraoperative and perioperative albendazole (ALB) treatment on the recurrence and/or secondary hydatidosis. METHODS: One hundred and one patients with hepatic hydatidosis were treated intraoperatively and perioperatively with ALB, in addition to surgery. Perioperative ALB treatment was given in a dose of 12-15 mg/kg/day. The ALB treatment was started 13.27 +/- 14.34 days before the surgery, and it was continued for 4.39 +/- 3.11 months postoperatively. A total of 1.7 microg/mL of ALB solution was used as a protoscolidal agent. The follow-up period was 134.55 +/- 51.56 months. RESULTS: Four patients died, with only one death was secondary to hydatid disease (cerebral eccinococcus). There was only one recurrence (1%) of hepatic hydatidosis. Early and late morbidity rates were 8.91% and 7.92%, respectively. CONCLUSION: Our results suggest that intraoperative and perioperative ALB is effective for the prevention of hepatic hydatidosis recurrence and/or secondary hydatidosis.
Albendazole* ; Echinococcosis ; Echinococcosis, Hepatic* ; Follow-Up Studies ; Humans ; Recurrence

Crusted scabies, characterized by hyperkeratosis and significant mite proliferation, is particularly prevalent in immunocompromised patients, such as those with systemic lupus erythematosus (SLE). This report presents a case of J.A., a 35-year-old female with SLE on prednisone and hydroxychloroquine, who developed pruritic erythematous papules on her palms and fingers. Over several months, these progressed to crusted hyperkeratotic plaques with fissures on her face, scalp, neck, and extremities.

Clinical evaluation revealed positive ink burrow tests and mineral oil preparation showing scabies mites and eggs. Histopathology confirmed the presence of intracorneal mites and scybala. Treatment involved permethrin 5% lotion applied daily for 14 hours over 7 days, followed by keratolytic soap and petroleum jelly twice weekly. Due to ivermectin unavailability, albendazole 400 mg was administered daily for three doses. Significant improvement was noted within two weeks.

Crusted scabies carries a high mite burden up to 4000 mites/gram of skin compared to 20 in typical scabies. The immunocompromised state in SLE patients, often marked by lower CD4+ counts and increased CD8+ T cells, lead to epidermal hyperproliferation. Early recognition and prompt combination treatment with permethrin and albendazole are essential for effective management. This case underscores the need for vigilance in diagnosing crusted scabies in patients with altered immune responses.

Albendazole, one of imidazole derivatives, is an new drug for the threatment of neurocysticercosis. In this study, effectiveness of albendazole and praziquantel for therapy for parenchymal or mixed neurocysticercosis was compared. Group A included 5 patients treated with albendazole for 7-10days. Three patients among them had been treated with praziquantel previously with partial response. During treatment, all patients presented with adverse reactions, such as mild fever, intense headache, vomiting, and seizure. After 3 months of treatment, the percentage of reduction in total number and total diameter of cysts on computed tomographic scan (CT) were 55.0%, 58.0% respectively. Group B included 10 patients treated with praziquantel for 5014days. Among them, only 2 patients presented with adverse reactions. The percentage of reduction in total number and total diameter of cysts on CT were 0%, 48.1% respectively. Froup C included 5 patients treated conservatively without any specific anticysticereal agent. Follow up CT after mean of 18.6 months had shown increase in total number (125%) and total diameter (151%) of cysts. Our results indicalte that both drougs were effective for therapy for parenchymal or mixed neurocysticercosis. But, albendazole I.
Albendazole* ; Fever ; Follow-Up Studies ; Headache ; Humans ; Neurocysticercosis* ; Praziquantel* ; Seizures ; Vomiting

OBJECTIVE: The authors report a case of racemose neurocysticercosis presented with myelopathy and hydrocephalus. The cllinical symtoms were not relieved even after the operations with albendazole medication. METHODS: A 44 year-old man was transferred due to headache, quadriparesis and epileptic fit. Preoperative magnetic resonance image(MRI) on brain and computed tomographic cisternogram on brain and upper cervical cord showed racemose cysticercosis on vermis, medulla and upper cervical cord. Two times operations(vesicles removal and adhesiolysis on cerebrospinal fluid pathway) were done with albendazole medication(15mg/kg/day, 30 days). The clinical symtoms were not relieved. Ventriculoperitoneal(V-P) shunt procedure was done and the symtoms were improved. CONCLUSION: The cause of aggravated hydrocephalus might be inflammatory reaction of the host to acute destruction of parasites due to albendazole in the brain.
Adult ; Albendazole ; Brain ; Cerebrospinal Fluid ; Cysticercosis ; Headache ; Humans ; Hydrocephalus* ; Neurocysticercosis* ; Parasites ; Quadriplegia ; Spinal Cord Diseases*

Disseminated cysticercosis is a rare form of cysticercosis in which the cysticerci spread out through the whole body. We report the first case of a 39-year-old Mongolian with disseminated cysticercosis. He visited our hospital with generalized tonic-clonic seizure. After extensive investigation from brain computed tomography (CT), spine magnetic resonance imaging (MRI), whole body MRI and pathologic biopsy, he was diagnosed as having cysticercosis involving the brain, subcutaneous tissue, and skeletal muscles through the whole body. We treated him with the albendazole in which case the followed MRI showed that numbers of cystic lesions were copiously decreased. We report an unsual case of disseminated cysticercosis treated with medical therapy.
Adult ; Albendazole ; Biopsy ; Brain ; Cysticercosis ; Humans ; Magnetic Resonance Imaging ; Muscle, Skeletal ; Neurocysticercosis ; Seizures ; Spine ; Subcutaneous Tissue