The study was conducted in Khanh Trung commune, Khanh Vinh district of Khanh Hoa province to assess the mosquito infection two years after DEC administration. Seventeen species of mosquito belonging to 5 genera have been found of which the main vector Wuchereria bancrofti was predominant. Indoor collection of Culex quinquefasdatus at daytime and nighttime was 3.5 and 2.3 individuals/house, respectively. Cx. vishnui was mainly found on the cattle sheds with an average density of 4.6 individuals/shed. A total of 578 mosquitoes of five species (Cx. quinqllefasciatus, An. vaglls, Cx. tritaeniorhynchus, Cx. vislznui, Cx. fuscocephalus) were dissected. None of them were positive with microfilaria.
Culicidae ; Albendazole

The authors had performed stereotactic surgery to diagnose and treat 2 cases of neurocysticercosis under the local anethesia. Generally, such the open surgery need a general anethesia which may increase the chance of brain parenchyml injury. However, the stereotactic surgery has the advantage of being an easy and precise procedure under local anethesia. The authors reviewed the literature and discussed the stereotactic surgery in the diagnosis, and treatment of neurocysticercosis.
Albendazole ; Brain ; Diagnosis ; Neurocysticercosis* ; Praziquantel

An oculogyric crisis which was resolved after intravenous injection of diazepam 10 mg developed in a 16-year-old girl after an oral dose of 400 mg of albendazole. Although ocular side effects of albendazole are rare, it can induce an alarming oculogyric crisis in some sensitive subjects. The mechanism of the oculogyric crisis is unclear.
Adolescent ; Albendazole* ; Diazepam ; Female ; Humans ; Injections, Intravenous

PURPOSE: The aim of this study was to evaluate long-term outcome of the intraoperative and perioperative albendazole (ALB) treatment on the recurrence and/or secondary hydatidosis. METHODS: One hundred and one patients with hepatic hydatidosis were treated intraoperatively and perioperatively with ALB, in addition to surgery. Perioperative ALB treatment was given in a dose of 12-15 mg/kg/day. The ALB treatment was started 13.27 +/- 14.34 days before the surgery, and it was continued for 4.39 +/- 3.11 months postoperatively. A total of 1.7 microg/mL of ALB solution was used as a protoscolidal agent. The follow-up period was 134.55 +/- 51.56 months. RESULTS: Four patients died, with only one death was secondary to hydatid disease (cerebral eccinococcus). There was only one recurrence (1%) of hepatic hydatidosis. Early and late morbidity rates were 8.91% and 7.92%, respectively. CONCLUSION: Our results suggest that intraoperative and perioperative ALB is effective for the prevention of hepatic hydatidosis recurrence and/or secondary hydatidosis.
Albendazole* ; Echinococcosis ; Echinococcosis, Hepatic* ; Follow-Up Studies ; Humans ; Recurrence

Toxocariasis has a broad clinical spectrum, from asymptomatic to systemic illness. However, cerebral toxocariasis has rarely been reported. We experienced a patient who presented with seizure and memory disturbance after treatment for visceral larva migrans of toxocariasis. Laboratory findings included eosinophilia, cerebrospinal fluid (CSF) pleocytosis, and positive results for toxocariasis in the serum and CSF. The patient showed marked improvement after combined albendazole and steroid treatment. This case indicates that cerebral toxocariasis is an unusual cause of cognitive dysfunction and seizure.
Albendazole ; Eosinophilia ; Humans ; Larva Migrans, Visceral ; Leukocytosis ; Memory ; Seizures ; Toxocariasis

Albendazole ; adverse effects ; Child, Preschool ; Drug Eruptions ; etiology ; Humans ; Tablets

Crusted scabies, characterized by hyperkeratosis and significant mite proliferation, is particularly prevalent in immunocompromised patients, such as those with systemic lupus erythematosus (SLE). This report presents a case of J.A., a 35-year-old female with SLE on prednisone and hydroxychloroquine, who developed pruritic erythematous papules on her palms and fingers. Over several months, these progressed to crusted hyperkeratotic plaques with fissures on her face, scalp, neck, and extremities.

Clinical evaluation revealed positive ink burrow tests and mineral oil preparation showing scabies mites and eggs. Histopathology confirmed the presence of intracorneal mites and scybala. Treatment involved permethrin 5% lotion applied daily for 14 hours over 7 days, followed by keratolytic soap and petroleum jelly twice weekly. Due to ivermectin unavailability, albendazole 400 mg was administered daily for three doses. Significant improvement was noted within two weeks.

Crusted scabies carries a high mite burden up to 4000 mites/gram of skin compared to 20 in typical scabies. The immunocompromised state in SLE patients, often marked by lower CD4+ counts and increased CD8+ T cells, lead to epidermal hyperproliferation. Early recognition and prompt combination treatment with permethrin and albendazole are essential for effective management. This case underscores the need for vigilance in diagnosing crusted scabies in patients with altered immune responses.

Drug-induced hepatotoxicity is injury to the liver as a result of drug exposure. Due to their unpredictable nature, drug-induced liver injuries pose a serious problem for clinicians, health agencies, and pharmaceutical firms. Albendazole is a benzimidazole with wide spectrum coverage as an antiparasitic drug. Very few cases of high-dose albendazole-induced hepatotoxicity have been reported so far, and no case in response to a single dose. A 25-year-old man presented to our hospital with dark urine. Twenty days prior to presentation, he took a tablet of albendazole (400 mg) as a prophylactic treatment for lumbricosis. Upon laboratory analysis, aspartate aminotransferase (AST) was 748 IU/L, alanine transaminase (ALT) was 939 IU/L, and total/direct bilirubin was 9.3/7.3 mg/dL. The patient was negative for viral markers (HAV, HBV, and HCV) and autoantibodies. Abdominal ultrasonography revealed no evidence of chronic liver damage. The pathology was compatible with drug-induced hepatotoxicity. The patient improved with conservative management only.
Adult ; Alanine Transaminase ; Albendazole ; Aspartate Aminotransferases ; Autoantibodies ; Benzimidazoles ; Bilirubin ; Biomarkers ; Drug-Induced Liver Injury ; Humans ; Liver

A 69-year-old male admitted to the psychological department due to delusion. One week later, he developed pneumonia and deep drowsy mental status. Despite improvement of pneumonia, his mental status got worse and he was referred to neurological department. The complete blood count tests showed repeated hypereosinophilia. The serologic tests revealed toxocariasis. He was treated with steroid and albendazole and his mental state rapidly improved. Toxocariasis is a common cause of reactive hypereosinophilia, which may be an underestimated etiology of reversible encephalopathy.
Aged ; Albendazole ; Blood Cell Count ; Delusions ; Humans ; Male ; Pneumonia ; Serologic Tests ; Toxocariasis*

Strongyloides stercoralis is an intestinal nematode which infects a large portion of the world's population especially in tropical areas and other hot, humid regions. Because of an opportunistic nature of the parasite, the infection is confined to the intestinal tract in immunocompetent hosts. But, in individuals having immunocompromised state, the parasite is augmented by autoinfection, resulting in hyperinfection and/or systemic dissemination. In Korea, several cases of strongyloides hyperinfection were reported since 1959, especially who had corticosteroid therapy and other immunosuppressive medications. We experienced a case of strongyloides hyperinfection, accompanied with terminal stage of stomach cancer. The patient responded to treatment with albendazole. After one month later, repeated follow-up stool exam revealed clearance of the larvae from the patient' feces. So, we report this case with the literature.
Albendazole ; Feces ; Follow-Up Studies ; Humans ; Korea ; Larva ; Nematoda ; Parasites ; Stomach Neoplasms* ; Stomach* ; Strongyloides stercoralis* ; Strongyloides*