1.Standard Value of Serum Alanine Aminotransferase: Is It Fixed or Varied?.
The Korean Journal of Gastroenterology 2014;64(4):179-181
No abstract available.
Alanine Transaminase*
2.Is alanine aminotransferase flare-up in nucleos(t)ide analogue treatment of chronic hepatitis B a promising, rather than a devastating, sign?.
Clinical and Molecular Hepatology 2017;23(2):125-127
No abstract available.
Alanine Transaminase*
;
Alanine*
;
Hepatitis B
;
Hepatitis B, Chronic*
;
Hepatitis, Chronic*
3.Changes of SGOT and SGPT enzym activities in blood of experimental mice after long-time exposing to Bassa
Journal of Medical and Pharmaceutical Information 2000;(4):29-31
100 white mice were divided in two groups, 50 mice for each one. The experimental group was exposed to Bassa 50EC with dose of 30 mg/kg body weight orally during 60 days. The other one was taken distilled water with a similar dose and time. The results showed that SGOT and SGPT enzyme activities in blood of experimental mice increased after exposing to Bassa.
Aspartate Aminotransferases
;
Alanine Transaminase
;
blood
4.Alanyl-tRNA Synthetase 2-Related Dementia with Selective Bilateral Frontal Cystic Leukoencephalopathy.
Guilhem CARLE ; Alexandre MORIN ; Camille NOIRAY ; Perrine ROY-JOLY ; Laurent COHEN ; Richard LEVY ; Simon SAMAAN ; Yann NADJAR
Journal of Clinical Neurology 2018;14(3):420-422
No abstract available.
Alanine-tRNA Ligase*
;
Dementia*
;
Leukoencephalopathies*
5.Aspartate and alanine aminotransferase in Fasciola hepatica.
Sun Hyo PARK ; Nyon Soo KWON ; Hi Sung LEE ; Chul Yong SONG
The Korean Journal of Parasitology 1983;21(1):41-48
The activity and distribution of aspartate aminotransferase (EC 2.6.1.1) and alanine aminotransferase (EC 2.6.1.2) in adult Fasciola hepatica have been studied. Fasciola hepatica was fractionated by differential centrifugation into nuclear, mitochondrial and cytosolic fractions. The activity of GOT and GPT was measured by the method of Reitman and Frankel. Isozyme patterns of those enzyme were also examined by DEAE-cellulose column chromatography. The results obtained were as follows: The activity of aspartate and alanine aminotransferase was about 0.55 unit and 0.92 unit per 1 g of Fasciola hepatica, respectively. The activity of those enzymes was relatively low compared with those in mammalian tissues. The distribution of aspartate aminotransferase in the subcellular organelles showed that 71 percent of the activity was in cytosolic, 24 percent in mitochondrial and 5 percent was in nuclear fraction. About 22 percent of the total alanine aminotransferase activity was found in the mitochondrial fraction, about 66 percent in the cytosolic fraction. Aspartate aminotransferase from cytosolic fraction was separated into two types of isozymes, whereas alanine aminotransferase from cytosolic fraction gave only one active peak on DEAE-cellulose column chromatography.
parasitology-helminth-trematoda
;
Fasciola hepatica
;
biochemistry
;
enzyme
;
aspartate aminotransferase
;
alanine
;
aminotransferase
;
alanine aminotransferase
6.Relationships with Alanine Aminotransferase Activity, and Anthropometric and Biochemical Measures in Obese Children.
Gyoung Bin YUN ; Jae Young KIM
Korean Journal of Pediatric Gastroenterology and Nutrition 2009;12(1):30-38
PURPOSE: To investigate the physical and biochemical parameters related with elevated serum alanine aminotransferase (ALT) levels in obese children. METHODS: One hundred forty-two obese or overweight children who visited the out-patient clinics of Chungnam National University Hospital between January 2006 and August 2008 were enrolled. Physical measures and biochemical tests were performed in all patients. Liver sonography was performed in 43 patients. They were divided into the following 2 groups based on ALT levels: group I, normal ALT levels (n=65); and group II, elevated ALT levels (n=77). We compared the physical measures, biochemical results, and ultrasonographic findings of the livers in both groups. Other causes of elevated serum ALT levels were ruled out. RESULTS: The male-to-female ratios were 1.6:1 in group I and 7.6:1 in group II. Among physical parameters, the waist circumference-to-height ratio and hip circumference-to-height ratio were significantly higher in group II (p=0.001 and 0.046, respectively). Among biochemical parameters, aspartate aminotransferase (AST), gamma-glutamyltransferase (gamma-GT), and total cholesterol levels were significantly higher in group II (p<0.001, 0.001, and 0.001, respectively). The AST/ALT ratio was <1 (mean, 0.55) and statistically lower in group II. There was a positive correlation between the serum ALT level and gamma-GT (p<0.001, r=0.750), and a positive correlation between the serum ALT level and the waist circumference-to-height ratio in group II (p<0.001, r=0.401). CONCLUSION: The results suggest that the waist circumference-to-height ratio and gamma-GT may be associated with elevated alanine aminotransferase activity in obese children.
Alanine
;
Alanine Transaminase
;
Aspartate Aminotransferases
;
Child
;
Cholesterol
;
gamma-Glutamyltransferase
;
Hip
;
Humans
;
Liver
;
Outpatients
;
Overweight
7.The Author's Response: Anti-Viral Therapy for Compensated Liver Cirrhosis Patients with Normal Alanine Aminotransferase.
Junggyu LEE ; Dong Hyun SINN ; Seung Woon PAIK
Journal of Korean Medical Science 2016;31(5):825-826
No abstract available.
*Alanine Transaminase
;
Antiviral Agents/therapeutic use
;
Humans
;
*Liver Cirrhosis
9.Postoperative Serum Glutamic Oxalacetic Transaminase and Serum Glutamic Pyruvic Transaminase Changes in Biliary Patients.
Korean Journal of Anesthesiology 1969;2(1):1-5
The SGO-T and SGP-T values were studied among 19 non-biliary surgical patients for control and 21 biliary tract surgical patients from Feb. to August 1969 in Chung Nam Medical Centor. The results obtained are as follows: 1. The SGO-T and SGP-T evels in the non-biliary surgical patients was in the normal range during pre-operative and postoperative days. 2. In patients with biliary disease SGO-T and SGP-T level were high beyond normal range on the pre-operative day. On the 1st postoperative day, these values were more elevated about 20 % and 11 %, respectively, but decreased gradually on the second and third postoperative days. 3 In biliary patients, the values were lower than pre-operative level on the 3rd postoperative day. On the other hand, values had not dropped to pre-operative level on the 3rd postoperative day in non-biliary patients.
Alanine Transaminase*
;
Biliary Tract
;
Hand
;
Humans
;
Reference Values
10.Changes of ALP , SGOT and SGPT Levels Following Halothane Anesthesia .
Korean Journal of Anesthesiology 1983;16(4):315-319
In the present study, an effort was directed to assess the changes of hepatic ensymes according to the exposed in short and long surgical cases under halothane anesthesia. 60 surgical cases were studied in two different group. Halothane anesthesia was given for less than 2 hours in the first group of 30 cases and for more than 2 hours in the second group of 30 cases. The results were compared with the normal values and summarized as follows: In the first group, the changes after halothane exposure for less than 2 hours were negligible. In the second group, SGOT and SGPT were elevated significantly and the number of enzyme-elevated cases were 5~6 greater in group 1.
Alanine Transaminase*
;
Anesthesia*
;
Aspartate Aminotransferases*
;
Halothane*
;
Reference Values