OBJECTIVEThe spectral imaging method was used to quickly identify the Cortex Dictamni pieces and its counterfeit alangium Chinese, which is a potential method would be applied to control the quality of the Cortex Dictamni pieces.

METHODStandard sample, 5 cortex dictamni samples and its counterfeit alangium Chinese of different sources were tested by the liquid crystal imaging instrument. The spectrum resolution was 5 nm, the spectral range was from 405 nm to 680 nm, and the spatial resolution was 50 lp x mm(-1). The characteristic spectrum curves were picked up from spectral cube and principal analysis method was used to analyze the results.

RESULTThe identification results by the spectral imaging method accorded well with the results by the traditional biology and chemistry analysis method.

CONCLUSIONThe spectral imaging analysis method can be used to identify the cortex dictamni pieces and its counterfeit alangium Chinense. The testing course is convenient, quick and noninvasive.

Alangiaceae ; chemistry ; Quality Control ; Rutaceae ; chemistry ; Spectrum Analysis ; methods

OBJECTIVE: To investigate the pathological change of mice organ intoxicated by Alangium Chinese and its poisoning mechanism. METHODS: Mice were intoxicated by gavage with extract of Alangium Chinese. Then the histopathologic examination was made for evaluating the pathological changes in the organs of the poisoned mice by HE staining. RESULTS: The main pathological changes included alveolar hemorrhage, pulmonary interstitial hemorrhage, sinus hepaticus expansion and congestion, hepatocyte edema, subarachnoid hemorrhage, congestion and hemorrhage of other organs. CONCLUSION The main target organs or tissue of Alangium Chinese are the lungs, liver and vascular smooth muscle. There is correlation between the toxic effect and the dosage.
Acute Disease ; Alangiaceae/chemistry* ; Animals ; Brain/pathology* ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Female ; Forensic Pathology ; Hemorrhage/pathology* ; Hepatocytes/drug effects* ; Kidney/pathology* ; Lethal Dose 50 ; Liver/pathology* ; Lung/pathology* ; Male ; Mice ; Muscle, Smooth, Vascular/drug effects* ; Plant Extracts/toxicity* ; Plant Roots/chemistry* ; Random Allocation ; Toxicity Tests, Acute