2.Effects of electrical acupuncture on the autonomic nervous system function after local anesthesia to the acupuncture points.
Masaaki SHINOHARA ; Yuriko IMAOKA ; Norihiro YAMAUCHI ; Koichi KAMIMURA ; Akira TANAKA ; Toru SATO
Journal of the Japan Society of Acupuncture and Moxibustion 1988;38(4):403-408
This study was performed to clarify whether local anesthesia or sympathetic ganglion block abolishes the effects of electrical acupuncture (EA) on the autonomic nervous system or not.
Twelve healthy adult volunteers and 24 patients are divided into the following three experimental groups of each 12. EA was performed to the traditional acupuncture points on the meridians (H7; SHENMEN and CX4; HSIMEN). (1) In control group, only EA was performed. (2) In stellate ganglion block (SGB) group, EA was performed after unilateral SGB. (3) In local anesthesia (LA) group, EA was performed after local anesthesia on the same acupuncture points. The measured parameters on the autonomic nervous system functions were heart rates, R-R intervals in ECG, blood pressure and deep tissue temperature.
Results are as follows; Means of heart rate decreased significantly by EA in both control and SGB groups. Systolic blood pressure, diastolic blood pressure and RR-CV showed no significant changes by EA in all groups. Deep tissue temperature of the anterior forearm ipsilateral to the stimulation side decreased significantly by EA in SGB group. Deep tissure temperature of the anterior forearm contralateral to the stimuli decreased significantly by EA in both control and SGB groups. In LA group, however, all parameters were not changed by EA.
In summary, the effects of electrical acupuncture on the autonomic nervous system were not much different between control and SGB groups. It seems that one side of stellate ganglion block dose not interfere with the effects of acupuncture. On the other hand, any changes on the autonomic nervous system by electrical acupuncture were not observed in LA group. The fact showed that local anesthesia abolishes the effects of acupuncture on site. Local anesthesia blocks peripheral nerves and nerve endings. Therefore, we conclude that the effects of acupuncture on the autonomic nervous system are transmitted through the peripheral nerves, especially through the sensory nerves.
3.Weekly Teriparatide Therapy Rapidly Accelerates Bone Healing in Pyogenic Spondylitis with Severe Osteoporosis.
Akira SHINOHARA ; Yutaka UENO ; Keishi MARUMO
Asian Spine Journal 2014;8(4):498-501
Pyogenic spondylitis is a frequently observed disease in orthopedics, and the number of cases is increasing. Some patients with pyogenic spondylitis suffer from vertebral destruction due to infection. The disease is typically treated with antibiotics, bed rest, spinal support, and lesion curettage; however, vigorous drug therapy against vertebral body destruction by pyogenic spondylitis has not been attempted. In this report, a case of pyogenic spondylitis with spinal destruction caused by infection and treated with once-weekly teriparatide administration is presented. Vertebral body erosion in cortical and cancellous areas by the infection was rapidly repaired after 6 weeks of once-weekly teriparatide treatment. Treatment with once-weekly teriparatide appears to be a new strategy for patients with severe osteoporosis suffering from pyogenic spondylitis.
Anti-Bacterial Agents
;
Bed Rest
;
Bone Density
;
Curettage
;
Drug Therapy
;
Humans
;
Orthopedics
;
Osteoporosis*
;
Quality of Life
;
Spondylitis*
;
Teriparatide*
4.Weekly Teriparatide Therapy Rapidly Accelerates Bone Healing in Pyogenic Spondylitis with Severe Osteoporosis.
Akira SHINOHARA ; Yutaka UENO ; Keishi MARUMO
Asian Spine Journal 2014;8(4):498-501
Pyogenic spondylitis is a frequently observed disease in orthopedics, and the number of cases is increasing. Some patients with pyogenic spondylitis suffer from vertebral destruction due to infection. The disease is typically treated with antibiotics, bed rest, spinal support, and lesion curettage; however, vigorous drug therapy against vertebral body destruction by pyogenic spondylitis has not been attempted. In this report, a case of pyogenic spondylitis with spinal destruction caused by infection and treated with once-weekly teriparatide administration is presented. Vertebral body erosion in cortical and cancellous areas by the infection was rapidly repaired after 6 weeks of once-weekly teriparatide treatment. Treatment with once-weekly teriparatide appears to be a new strategy for patients with severe osteoporosis suffering from pyogenic spondylitis.
Anti-Bacterial Agents
;
Bed Rest
;
Bone Density
;
Curettage
;
Drug Therapy
;
Humans
;
Orthopedics
;
Osteoporosis*
;
Quality of Life
;
Spondylitis*
;
Teriparatide*
5.A Study on a Phenomenon of a Propagated Sensation along the Channels (PSC) in Healthy Youths
Takao NAWATA ; Kenji MATSUOKA ; Toshikatsu KITADE ; Yoshinobu ODAHARA ; Shoji SHINOHARA ; Takaharu IKEUCHI ; Kazuhiro MORIKAWA ; Akira KAWACHI ; Masayoshi HYODO
Journal of the Japan Society of Acupuncture and Moxibustion 1983;32(4):294-298
In China, for years they have been studying the PSC to investigate scientifically the substance of traditional meridians. As we had been to there, we learned how to investigate it. According to their method we did it in Japan.
Objects were 340 healthy youths. The stimulated points were the well points in each meridian. The low frequency electroacupuncture (5-20Hz) was given to these points 30 minutes. Objects showed us their sensation or orally or by gesture.
We divided the result into 4 stages according to the chinese method;
salient…5 (1.5%)
comparatively salient…3 (0.9%)
slightly salient…7 (2.0%)
Non-salient…325 (95.6%)
In China, by the way, objects were 1, 000 people and it was 1.3%, 1.8%, 15.2% and 81.7%.
In this study, though it showed a low incidence of about 4.4% (about 18% in China), it was found that there was a phenomenon of the PSC.
6.Investigation of Pharmacists’ Intervention to Inhalational Skills and Effective Inhalation of Patients Taking Corticosteroids
Sumiko KONDO ; Yasushi TERADO ; Naoya TANAKA ; Seiichi KATO ; Akira TOYODA ; Yuki SHINOHARA ; Yoshitaka OTUKA ; Kazuhisa AOKI ; Takehiko YAJIMA
Japanese Journal of Social Pharmacy 2018;37(2):134-139
Inhaled corticosteroids should be taken continuously. As the methods of inhalation vary depending on the pharmaceutical preparations of inhaled corticosteroids, satisfactory effects cannot be expected without proper inhalation. This paper deals with the assessment of inhalational skills with the use of a manual of corticosteroid inhalation and a check sheet of patients’ performance. The effective inhalation as judge by the combination of the speed and the time needed for inhalation was assessed with the help of the training device for inhalation of each inhaled corticosteroid. The average scores of inhalational skills were increased significantly as follow ; aerosol : from 3.8 to 4.9 (p=0.035), Turbuhaler: from 2.6 to 3.0 (p=0.003), discus: from 4.9 to 6.0 (p<0.001). Among 7 in patients (38.9%) who were insufficient in inhalational ability, except for 1 patient who interrupted medication, 4 and 2 patients were improved in the speed and the time needed for inhalation, respectively. It was suggested to advise physicians to dispense alternative preparations of inhaled corticosteroids depending on the repeated evaluation of the inhalational ability.
7.Investigation of Pharmacists’ Intervention to Inhalational Skills and Effective Inhalation of Patients Taking Corticosteroids
Sumiko KONDO ; Yasushi TERADO ; Naoya TANAKA ; Seiichi KATO ; Akira TOYODA ; Yuki SHINOHARA ; Yoshitaka OTUKA ; Kazuhisa AOKI ; Takehiko YAJIMA
Japanese Journal of Social Pharmacy 2018;37(2):134-139
Inhaled corticosteroids should be taken continuously. As the methods of inhalation vary depending on the pharmaceutical preparations of inhaled corticosteroids, satisfactory effects cannot be expected without proper inhalation. This paper deals with the assessment of inhalational skills with the use of a manual of corticosteroid inhalation and a check sheet of patients’ performance. The effective inhalation as judge by the combination of the speed and the time needed for inhalation was assessed with the help of the training device for inhalation of each inhaled corticosteroid. The average scores of inhalational skills were increased significantly as follow ; aerosol : from 3.8 to 4.9 (p=0.035), Turbuhaler: from 2.6 to 3.0 (p=0.003), discus: from 4.9 to 6.0 (p<0.001). Among 7 in patients (38.9%) who were insufficient in inhalational ability, except for 1 patient who interrupted medication, 4 and 2 patients were improved in the speed and the time needed for inhalation, respectively. It was suggested to advise physicians to dispense alternative preparations of inhaled corticosteroids depending on the repeated evaluation of the inhalational ability.