1.A Case of Threatened Premature Delivery Successfully Treated with Hochuekkito
Keiko OGAWA ; Atsushi CHINO ; Akiko OMOTO ; Hitoshi KOIZUMI ; Nobuyasu SEKIYA ; Yuji KASAHARA ; Masaki RAIMURA ; Sumire HASHIMOTO ; Takao NAMIKI ; Katsutoshi TERASAWA
Kampo Medicine 2010;61(1):32-35
It is essential to prolong the term as possible in the treatment of threatened premature delivery. We report a case of threatened abortion successfully treated with hochuekkito. The patient was 31 year-old pregnant woman with lower abdominal pain. She was diagnosed to be at the risk of premature delivery on 21 weeks and 5 days of gestation. Intravenous ritodrine hydrochloride was started and she had to stay in bed. Severe side effects of ritodrine hydrochloride such as palpitation, tachycardia, tremor, nausea, and loss of appetite were appeared and she was consulted to our department on 23 weeks and 1 day of gestation. Those symptoms were markedly improved after administration of hochuekkito extract. She delivered a male infant of 1230g birth weight on 28 weeks of gestation. Hochuekkito suppressed severe side effects, and enabled to continue the infusion of ritodrine hydrochloride, suggesting the usefulness of Kampo therapy in the treatment of threatened premature delivery.
2.Efficacy of the pocket-creation method with a traction device in endoscopic submucosal dissection for residual or recurrent colorectal lesions
Daisuke IDE ; Tomohiko Richard OHYA ; Mitsuaki ISHIOKA ; Yuri ENOMOTO ; Eisuke NAKAO ; Yuki MITSUYOSHI ; Junki TOKURA ; Keigo SUZUKI ; Seiichi YAKABI ; Chihiro YASUE ; Akiko CHINO ; Masahiro IGARASHI ; Akio NAKASHIMA ; Masayuki SARUTA ; Shoichi SAITO ; Junko FUJISAKI
Clinical Endoscopy 2022;55(5):655-664
Background/Aims:
Endoscopic submucosal dissection (ESD) for residual or recurrent colorectal lesions after incomplete resection is challenging because of severe fibrosis. This study aimed to compare the efficacy of the pocket-creation method (PCM) with a traction device (TD) with that of conventional ESD for residual or recurrent colorectal lesions.
Methods:
We retrospectively studied 72 patients with residual or recurrent colorectal lesions resected using ESD. Overall, 31 and 41 lesions were resected using PCM with TD and conventional ESD methods, respectively. We compared patient background and treatment outcomes between the PCM with TD and conventional ESD groups, respectively. The primary endpoints were en bloc resection and R0 resection rates. The secondary endpoints were the dissection speed and incidence of adverse events.
Results:
En bloc resection was feasible in all cases with PCM with TD, but failed in 22% of cases of conventional ESD. The R0 resection rates for PCM with TD and conventional ESD were 97% and 66%, respectively. Dissection was significantly faster in the PCM with TD group (13.0 vs. 7.9 mm2/min). Perforation and postoperative bleeding were observed in one patient in each group.
Conclusions
PCM with TD is an effective method for treating residual or recurrent colorectal lesions after incomplete resection.