An 88-year-old man was diagnosed with right renal pelvic carcinoma and underwent laparoscopic right nephroureterectomy. On postoperative day 3, he developed aspiration pneumonia and sepsis and received antibiotic therapy. A central venous catheter (CVC) with an outer diameter of 12 G was inserted via the right internal jugular vein for total parenteral nutrition. On the day after catheterization, pulsatility reverse flow was observed in its lumen, and arterial mispuncture was suspected. Enhanced computed tomography (eCT) revealed that the CVC was inserted at the right internal jugular vein and had penetrated the right subclavian artery, and the CVC tip was positioned at the ascending aorta. Our team discussed the strategy, including direct arterial suture, endovascular therapy, and a percutaneous closure device. Because the patient was too frail to endure direct arterial closure, we chose endovascular therapy. Under general anesthesia, we pulled the CVC. Immediately afterwards, we deployed a GORE® VIABAHN® VBX using the transaxillary approach. On postoperative day 1, eCT showed that the GORE® VIABAHN® VBX was positioned from the right subclavian artery bifurcation, and there were no complications of hemorrhage, endoleak, or migration. His postoperative course was uneventful, and he was transferred to another hospital on postoperative day 16.

It has been reported that mucosal defects in the oral cavity caused by resection at a surgical site can be successfully repaired using a polyglycolic acid sheet, an absorbable artificial biomaterial, and fibrin glue spray. We report our experience of a case where bone surface coverage with a polyglycolic acid sheet and fibrin glue after exposure following resection of maxillary gingival leukoplakia led to a good outcome. The patient was a 64-year-old man with a keratotic white lesion on the right maxillary gingiva measuring 22 × 10 mm. He underwent resection of the lesion, which was diagnosed as maxillary gingival leukoplakia. The bone surface was exposed because of the operative extent and was covered with a polyglycolic acid sheet and fibrin glue. Wound healing progressed, and normal mucous membrane was seen at 5 weeks postoperatively. No relapse has occurred, and his progress is satisfactory.

A 72-year-old female was diagnosed with systemic lupus erythematosus and antiphospholipid syndrome (APS) in 2014 and was followed up. Severe mitral regurgitation coexisted with APS, but the case was nonsymptomatic, and surgery involved high risk. Therefore, the physicians continued their observation. In 2020, the patient experienced rheumatic severe mitral stenosis and shortness of breath on exertion. Paroxysmal atrial fibrillation and coronary stenosis were also detected. Therefore, we planned mitral valve replacement, tricuspid annuloplasty, coronary artery bypass, pulmonary vein isolation and left atrial appendage closure. During extracorporeal circulation (ECC), we performed coagulation management based on blood heparin concentration using HMS PLUS. Because the APS patient showed prolonged activated clotting time (ACT), and coagulation therapy based on ACT is unreliable. She was discharged from our hospital on postoperative day 23. No complications, including bleeding and thrombosis, were observed 2 years after the operation. We experienced a case of APS who underwent cardiac surgery and performed coagulation management by measuring heparin concentration during ECC. We targeted a 3.5 U/ml heparin concentration, and her clinical course was uneventful.