1.Determinants on aged population’s health expenditures in China
Chinese Journal of Health Policy 2015;(7):68-73
Objective:To provide references for policy-making on the establishment of a sound healthcare sys-tem for China’s aged population. Methods:Based on the framework of The Behavioral Model of Health Services Use and data from China Health and Retirement Longitudinal Study in 2011 , the Tobit model of aged population’s health expenditures is built. Results: Self-rated health conditions, chronic disease, medical insurance, endowment insur-ance, self-rated living standard, age, gender, marital status and urban-rural character are the significant determi-nants. Conclusions:The healthcare system for China’s aged population should be built through simultaneously apply-ing disease prevention and access facilitation policies and the characteristic differences of different groups of aged pop-ulation should be taken into consideration.
2.Analysis of the Proposal of A Hospital for the Pharmacoeconomic Evaluation of Community-acquired Pneumonia
Kai LI ; Hongbing XU ; Aixia MA
China Pharmacy 1991;0(02):-
OBJECTIVE:To improve the proposal put forward by a hospital on the pharmacoeconomic evaluation of community-acquired pneumonia.METHODS:The domestic pharmacoeconomic evaluation papers on the community-acquired pneumonia were evaluated.The problems lie in the proposal put forward by a hospital on the pharmacoeconomic evaluation of community-acquired pneumonia were analyzed and the measures for its improvement were put forward.RESULTS:The proposal had problems in research angle,determination of sample size,cost calculation,determination of quality of life etc.CONCLUSION:Measures for the improvement of the proposal should be put forward from the aspects of model construction,sample size determination,the design of quality of life table and sensitivity analysis.
3.Effects of Yiniao Recipe on serum antidiuretic hormone level and plasma ratio of cAMP to cGMP in rats with kidney-yang deficiency.
Wen SU ; Aixia HU ; Heng DU ; Kai YUAN ; Huifu XU
Journal of Integrative Medicine 2010;8(2):168-72
To investigate the effects of Yiniao Recipe, a compound traditional Chinese herbal medicine, on contents of serum antidiuretic hormone, and plasma cyclic adenosine monophosphate and cyclic guanosine monophosphate in rats with kidney-yang deficiency.
4.Analysis of chronic heart failure of coronary heart disease and ventricular arrhythmia
Kelu SUN ; Aixia LIAN ; Min XU ; Jingwu WANG ; Binbin LI
Chinese Journal of Primary Medicine and Pharmacy 2015;(5):699-701
Objective To analyze the treatment and pathogenetic condition of chronic heart failure of coro -nary heart disease(CHD) and ventricular arrhythmia (VA).Methods 100 patients with chronic heart failure were collected to observe the treatment of chronic heart failure and pathogenetic condition of VA .Results 44 cases occured VA and 56 cases without VA in 100 patients.NT-proBNP(3 110.00 ±522.00)pg/mL of VA group was sig-nificantly higher than that (2 200.00 ±486.00)pg/mL of non-VA group(t=8.996,P<0.05).LVEF(0.25 ± 0.08) of VA group was lower than that of non -VA group(0.41 ±0.98) (t=11.625,P<0.05).The occurrence (100.00%) of premature ventricular contraction ( PVC) of ≥70mm group in left ventricular internal diameter (LVID) was higher than that of 60 -69mm group (60.87%),50 -59mm group (37.04%),40 -49mm group
(15.38%) with statistically significant(χ2 =5.853,12.532,27.375,all P<0.05).The amount(44.20 ±12.90)mg of use βreceptor blockers of amiodarone group was significantly lower than that of non -amiodarone group(44.20 ± 12.90)mg (t=5.284,P<0.05).Conclusion NT-proBNP of CHEF of CHD and VA patients will improve and amiodarone can reduce the amount of use anti -heart failure drug .
5.Analysis of essential oil in cultivated Ephedra Sinica Stapf in Gansu Province
Aixia XU ; Bin GE ; Pingshun SONG ; Zhengmin ZHANG
Chinese Traditional Patent Medicine 1992;0(05):-
AIM: To analyze the chemical constituents of essential oil in Ephedra Sinica Stapf from Gansu Province. METHODS: The essential oil in Ephedra Sinica Stapf was extracted by steam distillation and analyzed by gas chromatography-mass spectrometry(GC-MS). RESULTS: 71 Compounds were identified from Ephedra Sinica Stapf of 3 different sources(Minqin,Zhenyuan and Gulang County),and contained 28 same components such as tetramethylpyrazine、linalool、?-terpineol、4-terpineol、d-?-terpineol、hexadecanoic acid and so on.The contents of d-?terpineol and hexadecanoic acid in Ephedra Sinica Stapf were the highest. CONCLUSION: Essential oils in Ephedra Sinica Stapf from Gansu Province do not contain 1-?-terpineol.
6.Effect of alcoholic extract from Fructus Polygoni Orientalis on lipid peroxidation in rat tissues
Bin GE ; Zhenming ZHANG ; Aixia XU ; Xiang GAO ; Xiaoyan LEI
Journal of Third Military Medical University 1988;0(06):-
Objective To study the activities of the alcoholic extract from Fructus Polygoni Orientalis (EFPO) against antioxidation. Methods The peroxidation in homogenate of rat heart, liver and kidney was induced by ?OH generation system Fe2++ascorbic acid. Malondialdehyde (MDA) was determined by TBA colorimetric method. Superoxide (O-2) from zymosan-stimulated neutrophils of rat was measured by NBT reduction method. H2O2-caused hemolysis of erythrocytes was measured by spectrometry. Results MDA in homogenate of heart, liver and kidney of rat that induced by ?OH generation system Fe2++ascorbic acid was inhibited by 6.3, 12.5, 25, 50, 100, 200 ?g/L EFPO; IC50 of EFPO to MDA in heart, liver and kidney was 31.8, 32.5 and 40.2 ?g/L respectively and its dose-effect relation was of negative relativity and the relative coefficient was -0.886, -0.874 and -0.918 (all P
7.Antitussive, Antiasthmatic, Antiinflammatory and Diuretic Effects of Herba Ephedrae Cultivated Artificially in Gansu Province
Bin GE ; Qiaoming WANG ; Aixia XU ; Jianxin ZHANG
China Pharmacy 1991;0(05):-
OBJECTIVE: To study the antitussive, antiasthmtic, anti-inflammatory and diuretic effects of Herba Ephedrae cultivated artificially in Gansu province and to compare which with the wild Herba Ephedrae. METHODS: Each pharmacological action index was determined by concentrated ammonia method, windpipe capacity method, pinna swelling method and metabolic cage method. RESULTS: Both of the two kinds of Herba Ephedrae could reduce the cough responses of mice, resist the spasmodic contraction of the tracheal smooth muscles, reduce the swelling of auricle of mice and increase urine volume of rats. CONCLUSIONS: Herba Ephedrae cultivated artificially in Gansu province are equivalent to the wild one in terms of the antitussive, antiasthmtic, anti-inflammatory and diuretic effects thus it can serve as a substitute for the wild one.
8.Study on Pharmacological Actions of Kangleifenghsi Capsules
Shan WAN ; Ling SONG ; Weihong XU ; Aixia ZHAO ; Xiumei YUE ;
Chinese Traditional Patent Medicine 1992;0(08):-
Objective: To study the anti inflammatory, antipyretic and analgetic actions of Kangleifengshi capsules. Methods: The anti inflammatory action was observed by adjuvant arthritis and other inflammatory models. The antipyretic action was surveyed by pyretic rat induced by yeast. The analgetic effect was tested by sprain mice. Results: The experiments proved that the capsule has significant preventing and treating effects on rat adjuvant arthritis, strong inhibition on many kinds of inflammatory models, antipyretic action on pyretic rat induced by yeast and notable angalgetic action on sprain mice induced by acetic acid. Conclusion: Kangleifengshi Capsules has better anti inflammatory, antipyretic and analgetic effects.
9.Effects of a polysaccharide from CCL on inhibiting oxygen free radical threshold of senile mice model
Xiguang CAI ; Aixia XU ; Bin GE ; Xiang GAO ; Shehua YANG
Journal of Third Military Medical University 2003;0(13):-
Objective To study the effect of a polysaccharide from cuscuta chinensis lam (PCCL) on antisenility and its mechanism. Methods Sixty Kunming mice were randomized into 6 groups. The three PCCL groups were administrated with PCCL of 100, 200, 400 mg?kg -1?d -1 orally, the positive control group with vitamin E of 200 mg?kg -1?d -1, the model group and control group with the same volume of control solution only. At the same time, the model group, the positive group and the three PCCL groups were subcutaneously injected of 5% D-gal at the dose of 0.5 ml at the nape, and the control with the same volume of saline solution. Seven weeks later, the MDA, SOD activity, GSH-PX activity in the liver and kidney of mice and lipofuscin (LF) in mouse brain were detected with the methods of TBA, Nitrate, DTNB and Sohal, respectively. The data were analyzed with SPSS software and the data between groups were analyzed with one-factor variance analysis. Results Thymus index and spleen index dropped, LF rose in brain, malondialdehyde (MDA) content rose and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) dropped in liver and kidney in senile mouse model. PCCL administration of 100, 200, 400 mg?kg -1?d -1 made thymus index and spleen index rising, LF dropping in brain, MDA content dropping,SOD and GSH-PX LF rising in liver and kidney of senile mouse model. Conclusion PCCL may postpone senility, which mechanism probably connected with rising immunity, eliminating oxygen free radicals and antilipoperoxidation.
10.Effect of Group Education Intervention in Self-control on Schizophrenics
Xuesheng WANG ; Aixia XU ; Hongzhi MA ; Xin ZHOU
Chinese Journal of Rehabilitation Theory and Practice 2009;15(6):580-582
Objective To explore the rehabilitation effect of group education intervention in self-control on schizophrenic patients. Methods 112 schizophrenic patients were divided into study group (56 cases) and control group (56 cases). Two groups were treated with antipsychotics. The control group was subjected to general healthy education, while the study group received education intervention of self-control. All patients of two groups were assessed by Self-care Behavior Questionnaire(SCBQ), Brief Psychiatric Rating Scale(BPRS) and Social Disability Screening Schedule(SDSS) before and affter intervention, and drug-compliance was also assessed.Results After one year, the total score of SCBQ was significantly higher in the study group than in the control group, while the total scores of BPRS and SDSS were significantly lower in the study group than in the control group (P<0.01); Drug-compliance was significantly more in the study group than in the control group(P<0.01).Conclusion Group education intervention of self-control can improve distinctly the ability of self-control disease, have positive effect on remission psychical symptom, and improve the social function and retention psychosomatic healthy.