1.Soft tissue manifestations of mycobacterial infection in patients with rheumatic diseases.
Aisha LATEEF ; Sheila VASOO ; Mee Leng BOEY
Annals of the Academy of Medicine, Singapore 2007;36(2):152-153
Adult
;
Fatal Outcome
;
Female
;
Humans
;
Immunocompromised Host
;
Immunosuppressive Agents
;
therapeutic use
;
Middle Aged
;
Mycobacterium Infections
;
complications
;
Opportunistic Infections
;
complications
;
Prednisolone
;
therapeutic use
;
Rheumatic Diseases
;
complications
;
Soft Tissue Infections
;
complications
2.Case reports of transient loss of vision and systemic lupus erythematosus.
Annals of the Academy of Medicine, Singapore 2007;36(2):146-149
INTRODUCTIONNeuropsychiatric manifestations can occur in up to two-thirds of patients with systemic lupus erythematosus (SLE). The presentations as well as the underlying immunopathogenic mechanisms can be heterogeneous and therefore have an enormous impact on therapeutic options.
CLINICAL PICTUREWe describe 2 patients who presented similarly with acute onset binocular reversible visual loss. The first patient had anti-phospholipid syndrome and optic neuritis, while the second patient suffered from posterior reversible leukoencephalopathy syndrome.
TREATMENTPatient one was treated with anti-coagulation and immunosuppression while the second patient required the withdrawal of immunosuppression and supportive therapy.
OUTCOMEBoth patients responded favourably and had complete visual recovery.
CONCLUSIONSDifferent management strategies have to be employed for similar presentations having different aetiologies, underscoring the need for constant clinical vigilance.
Adult ; Antiphospholipid Syndrome ; complications ; etiology ; Brain Diseases ; etiology ; immunology ; Epilepsy, Tonic-Clonic ; etiology ; Female ; Humans ; Lupus Erythematosus, Systemic ; complications ; microbiology ; physiopathology ; therapy ; Lupus Vasculitis, Central Nervous System ; diagnosis ; Magnetic Resonance Imaging ; Optic Neuritis ; etiology ; Salmonella Infections ; complications ; Salmonella enteritidis ; Time Factors ; Vision Disorders ; etiology ; immunology
4.Acute medical unit: experience from a tertiary healthcare institution in Singapore.
Wei-Ping GOH ; Hui Fen HAN ; Uma Chandra SEGARA ; Geraldine BAIRD ; Aisha LATEEF
Singapore medical journal 2018;59(10):510-513
Singapore's healthcare system is under strain from the rising demands of an increasing and ageing population, resulting in delayed specialist care for patients presenting to the emergency department and requiring admission. Acute assessment units have been developed elsewhere but are not well established in local healthcare. Our institution extended our acute medical team to form an acute medical unit (AMU), in which focused internist-led teams are stationed on site to rapidly assess and re-triage patients. All patients (excluding those with very complex conditions) are admitted to the AMU and managed by internists who provide holistic, patient-centric care with better ownership, improved efficiency and less fragmentation. Patients can receive timely access to medical interventions and stable patients can benefit from early supported discharge, anchored by the nursing, allied health and transitional care teams. Given the ageing patient population with multiple comorbidities, this integrated model with exceptional outcomes is highly suitable for Singapore.