Objective:To observe the e ects Of Jianpitongmai soup in regulating blood fat.Methods:120 cases of hyperlipidemia patients were randomly divided into two groups:Jianpitongmai group with 60 cases and simvastatin control group with 60 cases.To compare the treatment e cacy after 8 weeks.Results:Jianpitongmai soup can signi cantly improve indicators of blood fat(P0.05).Conclusions:Jianpitongmai soup can control blood fats comprehensively,and the e ect will be cumulative with the continuation of treatment.

Objective To investigate the effect of Omaha system intervention on social psychology of the elderly,and to provide evidence for effective intervention in elderly with homebound state.Methods 218 cases with homebound conditions were divided into intervention group and control group by random digits table with each group 109 cases.The intervention group accepted intervention including health education,treatment procedures,case management,supervision of the four aspects of 1-3 times a week according to Omaha intervention system for a period of 3 months.The control group was the blank control.And Omaha evaluation form was used to evaluate social psychological and physical effect before and after the intervention.Results 3 months after the intervention,except physiology in the field of neuromusculo-skeletal function of two groups had no significant difference (t=2.03,P＞0.05),scores in the intervention group in the field of physiology (like the circulation) were higher than the control group,the difference was statistically significant [(1 1.20±2.03) vs.(8.72±1.36),P＜0.05].As for psychology (like mental health),scores of intervention group were higher than that of the control group [(12.53±1.42) vs.(8.63±1.33),t=20.12,P＜ 0.05].Conclusions Omaha system can effectively improve the quality of life of elderly with homebound state and maintain their physiological,social and psychological function.

Objective Cancer-related fatigue (CRF) is a key in the management of cancer patients' clinic syptoms.This article investigated the status quo of nurses' knowledge and attitude towards CFR.Methods THe method of cross-sectional survey and questionnaire was used to investigate the knowledge and attitude towards CRF among nurses from related departments of three Grade III hospitals in Nanjing.Results 142 nurses answered the questionnaire.The average correct rate was 76.25%, among which nurses from the oncology department had better congition rate than nurses from other medical and surgical departments (84.3%, 75.98%, 79.57%) , representing significant difference (P<0.05).64.79% of the nurses found the relatives of cancer patients and nurses often fail to understand cancer patients;complaint of fatigue, 76.76% of nurses assumed there is lack of communication in fatigue between patients and medical staff.94.36% of nurses agreed medical institutions should strengthen the management of CRF.Conclusion At present, the clinical nurses have inadequate knowledge about CRF, which should be enhanced in future work.

Objective To investigate the curative effect and nursing of medical ozone autohemotherapy in clinical treatment. Methods 45 cases of cerebral infarction patients with medical ozone self blood therapy spells, psychological guidance and health education before operation in the sterile operation, postoperative nursing, education results. Results 45 cases of cerebral infarction in patients with very good completed treatment, 2 cases because of dizziness aggravated, 2 cases of vascular puncture for difficult to stop treatment, the rest were different extent achieved certain effect. Conclusions the clinical experiment showed that the nursing, preoperative education, psychological guidance and sterile operation, postoperative is an effective measure for ensuring medical ozone autohemotherapy smooth finish.

Objective:To investigate the effects of Zhitaiqing Granule on aortic endothelial cells in rabbit with experimental atherosclerosis. Methods:10 New Zealand rabbits were selected as blank control randomly and fed with normal forage,while the rest rabbits were fed with high-fat forage in formula A. After six weeks,hyperlipidemia models were formed and they were randomly divided into model group,Zhitaiqing treatment group,simvastatin control group and hawthorn tablet control group. From the 7th week,rabbits in treatment and control groups were fed with corresponding drugs while the blank and model groups with the same quantity of normal saline by lavage. After 11 weeks lavage,total cholesterol (CHO),triglyceride (TG),high-density lipoprotein cholesterol (HDL-C),apolipoprotein AI (apo AI),apolipoprotein B (apo B).were detected. With the help of optical microscope,the pathological changes of the aortic arch,thoracic aorta and abdominal aortic intima were observed. Results:In Zhitaiqing group,CHO,LDL-C,and ApoB reduced dramatically (P

Objective To observe the curative effect of magnesium isoglycyrrhizinate in prevention of liver injury induced by oxaliplatin .Methods The control group used oxaliplatin ,leucovorin ,5‐fluorouracil chemotherapy ,the treatment group were treated with oxaliplatin ,leucovorin ,5‐fluorouracil chemotherapy and simultaneous magnesium isoglycyrrhizinate were used at the same time .With 28 d for 1 course of treatment ,the treatment period consisted of 2‐4 courses ,observation of pa‐tients and the proportion of liver injury were made .Results In the control group ,liver injury incidence rate was 44 .4% ,the rate of injury was 19 .4% in treatment group ,there was significant difference between the two groups (P<0 .01) .Conclusion Magnesium isoglycyrrhizinate could be effective in prevention of oxaliplatin induced liver injury .

Thirst is one of the common complaints of critically ill patients, persistent and intense thirst is closely related to a variety of negative emotions, such as anxiety, depression, etc., which can cause restlessness, sleep disorders, and reduce the quality of life; at the same time, it can cause bacterial growth in the patient′s oral cavity, increasing the risk of secondary infection, thereby delaying the recovery of the disease and prolonging the length of ICU hospitalization. Therefore, this article reviews the current status, risk factors, and intervention strategies of thirst in critically ill patients in order to provide a reference and basis for medical staff to carry out thirst intervention measures in critically ill patients.

Objective To evaluate the curative effects of vacuum sealing drainage equipment on prevention and treatment of subcutaneous effusion after breast cancer radical correction. Methods A total of 122 cases of breast cancer patients from June 2006 to June 2012 were randomly divided into control group ( n=62) and intervention group (n=60). The patients of control group underwent the conventional drainage while the patients of intervention group received the vacuum sealing drainage. The situation of subcutaneous effusion, infection, skin flap necrosis, decannulation time as well as day flow conditions in two groups were observed and compared. Results The incidence of subcutaneous effusion, infection and skin flap necrosis in control group were 12. 9%, 6. 4%, 8. 1% respectively. In intervention group, the incidence rate of subcutaneous effusion was 1. 7%, and no infection, and skin flap necrosis had been observed (χ2 =7. 90,8. 31,9. 12;P<0. 01). The extubation time and day flow conditions in control group was(6. 8 ± 2. 3) d and (70 ± 38) ml, while the interventiongroupwere(10.5±3.1)dand(105±28)mlwithstatisticalsignificance(t =2.10,3.95;P <0. 05). Conclusions Simple vacuum sealing drainage device can not only prevent the subcutaneous effusion, infection and skin flap necrosis after breast cancer radical correction, but also can realize the early extubation, therefore it is worthy of promotion in clinical.

Objective:To explore the correlation between screen sedentary behavior and sleep quality of the elderly people in the community, so as to provide a reference for improving sleep quality of the elderly people in the community.Methods:From November 2021 to April 2022, 627 older adults from 3 communities in Hefei, Anhui Province were selected as the research objects using the convenience sampling method. The General Information Questionnaire, Measure of Older Adults' Sedentary Time Questionnaire, and Pittsburgh Sleep Quality Index (PSQI) were used to investigate the elderly people in the community. Pearson correlation analysis was used to analyse the correlation between screen sedentary behavior and sleep quality of the elderly people in the community. The influencing factors of sleep quality were assessed by Binary Logistic regression. A total of 660 questionnaires were distributed and 627 valid questionnaires were recovered, with an effective recovery rate of 95.0% (627/660) .Results:The screen sedentary behavior time of 627 elderly people in the community was (3.53±1.52) h/d, the total score of PSQI was (7.11±3.58) , and the incidence of sleep disorders was 37.48% (235/627) . Pearson correlation analysis showed that screen sedentary positively correlated with the total score of PQSI ( r=0.466, P<0.01) . Binary Logistic regression analysis results showed that the screen sedentary behavior ( OR=1.892, 95% CI: 1.638-2.185) , female ( OR=1.963, 95% CI: 1.120-3.441) , self-reported poor health status ( OR=3.332, 95% CI: 1.380-8.043) were the risk factors of sleep quality of the elderly people in the community. Conclusions:The screen sedentary behavior and sleep quality of the elderly people in the community are not optimistic, and the screen sedentary behavior, female, self-reported poor health status are the risk factors of sleep quality of the elderly people in the community. Community health staff should develop targeted intervention strategies to help the elderly people in the community reduce screen sedentary behavior time and improve sleep quality.

Objective To analyze the risk factors for lung infection in patients with craniocerebral injury after tracheotomy through Meta-analysis and provide a scientific reference for its prevention. Methods The inclusion and exclusion criteria were determined and the search strategies were designed. Two researchers independently searched both English and Chinese databases such as Cochrane Library, EMBASE, PubMed, CNKI, Wanfang and VIP (taking brain injury, craniocerebral injury, traumatic brain injury, tracheotomy, lung infection, pulmonary infection, risk factor, influencing factor and promotive factor as the key words) for literatures published since the databases were built to April 28th, 2019. RevMan 5.3 was used to analyze the data after the quality of literatures were assessed. Results Totally 9 articles were included, including 2112 patients with craniocerebral injury. Meta-analysis showed that diabetes [OR=3.36, 95％CI(2.49, 4.54),P< 0.01], use of hormones [OR=2.52,95％CI(1.83, 3.45),P< 0.01], Glasgow Coma Scale (GCS) score [OR=2.92,95％CI(1.95, 4.37),P< 0.01], hypoproteinemia [OR=3.18,95％CI(2.20, 4.60), P< 0.01], aspiration [OR=3.18, 95％CI(2.24, 4.51),P < 0.01], smoking [OR=1.87,95％CI(1.16, 3.00), P < 0.01], non-irrigable tracheal cannula [OR=2.54, 95％CI(1.71, 3.77),P<0.01]and tracheotomy time (>7 d) [OR=2.32, 95％CI (1.42, 3.79);P< 0.01]were the influencing factors for lung infection in patients with craniocerebral injury after tracheotomy. Conclusions Existing evidence shows that combined with diabetes, use of hormones, high GCS score, hypoalbuminemia, occurrence of aspiration, use of non-irrigable tracheal cannula, smoking, tracheotomy time > 7 d were independent risk factors for lung infection in patients with craniocerebral injury.