Objective To explore the effect of Renshen Jianxin Capsule on insulin resistance and coagulation in coronary heart disease. Methods Angina patients with Qi dificiency and blood stasis were randomly divided into Renshen Jianxin Capsule group (30 patients, treated by Renshen Jianxin Capsule and common western medicine) and metformin group (30 patients, treated by metformin and common western medicine). The changes of blood glucose, insulin sensitivity index (ISI), plasminogen activator inhibitor-1 (PAI-1) were observed after six weeks. Results Blood glucose and PAI-1 were decreased, ISI was improved significantly after treatment of Renshen Jianxin Capsule. There was no significant difference of PAI-1 in metformin group. Conclution Renshen Jianxin Capsule has similar effect with metformin in improving insulin resistance and better effect in improving coagulation.

The clinical classification of metastatic spinal tumors is based on the degree of malignancy, nervous system function, osteoclasia, and prognosis of patients. The application of this classification system is relatively simple. The assessment and evaluation of patients to estimate the period of survival can guide the individualized treatment of patients. Patients with clear surgical indications can choose to undergo a palliative operation, tumor resection, or total spondylectomy. Alternatively, other patients can opt to have mini-mally invasive surgery aside from the normal surgical approach. Stereotactic radiotherapy and intensity-modulated radiation therapy combined with the use of radiofrequency ablation, radiation, and other therapies can achieve local tumor control, relieve pain, and main-tain normal neurological function. Thus, the quality of life of the patient is improved. Percutaneous vertebroplasty, radiofrequency abla-tion, spinal endoscopy, and other modern forms of minimally invasive surgery will have more applications in the treatment of spinal metastatic tumors.

[Objective] Discuss the influence of Taoist thought of health, in order to establish Taoist theory support for Chinese medicine keeping in good health.[ Method]Through discussing the influence to health maintenance by the Taoist theory of laissez-faire, returning to nature, prevention of disease, venerating yin and softness, to summarize the importance of Taoist thought in health maintenance. [Result]Taoist thought plays an important role in Chinese medicine health maintenance, Taoist thought emphasizes nihility and innocence, returning to nature, and making life to return to original state, prevention treatment of disease, and also pays attention to the protection of yin, emphasizing the regulation of five internal organs. [Conclusion]Taoist thought is one of the important thoughts inheritance for thousands of years in China, the quietness of the laissez-faire Taoism, the thought of returning to nature, the prevention treatment of disease thought in tonifying physical and spiritual, the thought of venerating yin and softness, al have guiding significance for TCM in health maintenance.

The level of serum lipid peroxide in rat is increased as the age of rat increased gradually. When the animals were injected with sodium selenite (0.1mg/kg) and vitamin E (4mg/kg) for five weeks the serum lipid peroxide level was decreased, the combined use of sodium selenite and vitamin E could decrease the level of SGPT apparently.

Lifelong blood cell production is achieved by the capacity of hematopoietic stem cell(HSC) to differentiate and self-renew.A growing body of evidence suggest that DNA damage induced HSC senescence may be the principal mechanism of aging and HSC exhaustion in response to the stress exposure.Understanding the mechanisms of HSC senescence will help to find new therapeutics that can ameliorate HSC injury induced by chemo-and radiotherapy,elucidate the molecular mechanisms whereby leukemia/cancer stem cell arise and evade cancer therapy by escaping senescence,and identify the novel molecular targets for intervention.

OBJECTIVE To investigate the incidence,symtoms and prognosis of hospital infection by Mucor after liver transplantation.METHODS The clinical data of all the patients with complicated hospital infection orthotopic by Mucor after orthotopic liver transplantation were analyzed restrospectively.RESULTS There were 9 cases with complicated hospital infection by Mucor from in 750 liver transplant recipients.Seven cases developed superficial incisional infection with delayed healing and rapid increased secretion on the surface of incisions.All of them recovered after antifungal therapy.Two cases had pulmonary Mucor infection combined with bacteria and died of multi-organ failure.CONCLUSIONS The incidence of hospital infection by Mucor in liver transplant recipients is about 1%.The most common symtoms are superficial incisional infection and the patients recover well.However,the cases with complicated pulmonary Mucor infection are difficult to treat and have a poor prognosis.

Anemia, Hemolytic ; complications ; Child ; Humans ; Pneumonia ; complications

Objective Combined with the patients arthritis symptoms and signs,TCM syndrome differentiation of rheumatoid arthritis was undertaken to investigate TCM syndrome distribution.Methods A total of 656 patients of rheumatoid arthritis from October 1st 2010 to January 1st 2012 hospitalized in Shandong Qingdao Combine Traditional Chinese and Western Medicine hospital were untaken TCM syndrome differentiation according to their symptoms and signs.Results The main syndromes of rheumatoid arthritis patients were cold-dampness blockage syndrome and liver and kidney deficiency syndrome,followed by cold-wind blockage syndrome,deficiency of Qi and blood syndrome,and dampness-heat blockage syndrome.The highest scores of ESR and C reactive protein appeared in dampness-heat blockage syndrome group,with ESR being (56.23 ± 13.87) ram/h,CRP being (69.49± 21.56) mg/L.These values showed significant difference than other syndrome group (P ＜ 0.05).There was no significant difference of rheumatoid factor,immunoglobulin IgG,IgA,IgM values among these syndrome groups (P＞0.05).Comparison of age,course of disease showed the liver and kidney deficiency syndrome group (age was 59.3± 12.15,duration was 7.98 ± 3.76)and Qi and blood deficiency syndrome group (age was 52.5± 11.5,duration was 6.56±3.12) were significant higher than cold-dampness blockage syndrome,damp-heat blockage syndrome group and cold-wind blockage syndrome group with the age of (46.2± 11.12) and (45.8± 11.60),(43.5± 12.50) respectively and course of (5.56±2.76),(5.78±2.98),(5.12±2.32) respectively (P＜0.05).Conclusion The main TCM syndromes of rheumatoid arthritis patients in Qingdao area were cold-dampness syndrome,liver and kidney deficiency syndrome,followed by cold-wind blockage sydrome,Qi and blood deficiency syndrome,damp-heat blockage syndrome.Among all syndromes,relatively high age and disease course of patients appeared in liver and kidney deficiency syndrome and Qi and blood deficiency syndrome.

Objective To study the relationship between the microvessel damage and the death rate of tumor cells and determine role of microvessel damage in the tumoricidal effect of hyperthermia.Methods H22 hepatoma cells were inoculated in the right hind legs of KM mice with immunosuppression.Local hyperthermia was administered to these mice which were divided randomly into 10 groups (8 in each group),which included groups of 3,6,12,24,48,72 and 96 h after hyperthermia for 30 min and groups of hyperthermia for 15,30 and 45 min.The tumor tissues were analyzed by flow cytometry(FCM)and immunohistochemistry.The cultured H22 cells were also given hyperthermia for 15,30,45 min and analyzed by FCM.Results The apoptotic rate(0.115±0.008)was higher in the initiation phase of hyperthermia in vitro,then the necrotic rates rose gradually.The difference between in vivo and in vitro was significant in hyperthermia of the same time about death rate(P＜0.05).A strong positive linear correlation(r=0.844)was observed between the death rate of tumor cells and MVD.Conclusion Microvessel damage plays the cardinal role in tumoricidal effect of hyperthermia.

Objective To study Aeromonas hydrophila infection and the clinical status of the major causative factor Aerolysin gene.Methods Clinical isolates of Aeromonas hydrophila was collected from 2012 to 2013 year in People’s Hospital of Shenzhen Longhua Branch.Its identification and antibiotic susceptibility testing was analyzed by VITEK 2 compact.Clinical resistance rates and distribution was analyzed by WHONET5.6 software.Polymerase chain reaction (PCR)was used to de-tect the Aerolysin gene form in chromosomes and plasmids extracted genome.Results The clinical total of 48 isolated Aero-monas hydrophila ,distributed in 16 clinical samples of sputum,blood 11,10 secretions,urine 7 and stool 4.Distribution in ward decentralized,the central tendency was not detected.Drug resistance rates to ampicillin,ampicillin/sulbactam and ce-fazolin reached more than 80%,while amikacin,cefepime,levofloxacin,piperacillin/tazobactam and imipenem was low 10%or less.43.7% strains carried the Aerolysin gene.39.5% of Aerolysin gene was found on chromosome genome.Conclusion Aeromonas hydrophila clinical infection existed in dispersed form,most of which carried Aerolysin gene in chromosome ge-nome.Aeromonas hydrophila had serious resistance to penicillins and first generation cephalosporin,but to broad-spectrum drugs maintaining high sensitivity.Precaution of Aeromonas hydrophila ,as an important condition pathogenic bacteria,is some significant for preventing it’s proliferation of drug-resistant strains.