Objective To explore the effect of Renshen Jianxin Capsule on insulin resistance and coagulation in coronary heart disease. Methods Angina patients with Qi dificiency and blood stasis were randomly divided into Renshen Jianxin Capsule group (30 patients, treated by Renshen Jianxin Capsule and common western medicine) and metformin group (30 patients, treated by metformin and common western medicine). The changes of blood glucose, insulin sensitivity index (ISI), plasminogen activator inhibitor-1 (PAI-1) were observed after six weeks. Results Blood glucose and PAI-1 were decreased, ISI was improved significantly after treatment of Renshen Jianxin Capsule. There was no significant difference of PAI-1 in metformin group. Conclution Renshen Jianxin Capsule has similar effect with metformin in improving insulin resistance and better effect in improving coagulation.

[Objective] Discuss the influence of Taoist thought of health, in order to establish Taoist theory support for Chinese medicine keeping in good health.[ Method]Through discussing the influence to health maintenance by the Taoist theory of laissez-faire, returning to nature, prevention of disease, venerating yin and softness, to summarize the importance of Taoist thought in health maintenance. [Result]Taoist thought plays an important role in Chinese medicine health maintenance, Taoist thought emphasizes nihility and innocence, returning to nature, and making life to return to original state, prevention treatment of disease, and also pays attention to the protection of yin, emphasizing the regulation of five internal organs. [Conclusion]Taoist thought is one of the important thoughts inheritance for thousands of years in China, the quietness of the laissez-faire Taoism, the thought of returning to nature, the prevention treatment of disease thought in tonifying physical and spiritual, the thought of venerating yin and softness, al have guiding significance for TCM in health maintenance.

The level of serum lipid peroxide in rat is increased as the age of rat increased gradually. When the animals were injected with sodium selenite (0.1mg/kg) and vitamin E (4mg/kg) for five weeks the serum lipid peroxide level was decreased, the combined use of sodium selenite and vitamin E could decrease the level of SGPT apparently.

Lifelong blood cell production is achieved by the capacity of hematopoietic stem cell(HSC) to differentiate and self-renew.A growing body of evidence suggest that DNA damage induced HSC senescence may be the principal mechanism of aging and HSC exhaustion in response to the stress exposure.Understanding the mechanisms of HSC senescence will help to find new therapeutics that can ameliorate HSC injury induced by chemo-and radiotherapy,elucidate the molecular mechanisms whereby leukemia/cancer stem cell arise and evade cancer therapy by escaping senescence,and identify the novel molecular targets for intervention.

The clinical classification of metastatic spinal tumors is based on the degree of malignancy, nervous system function, osteoclasia, and prognosis of patients. The application of this classification system is relatively simple. The assessment and evaluation of patients to estimate the period of survival can guide the individualized treatment of patients. Patients with clear surgical indications can choose to undergo a palliative operation, tumor resection, or total spondylectomy. Alternatively, other patients can opt to have mini-mally invasive surgery aside from the normal surgical approach. Stereotactic radiotherapy and intensity-modulated radiation therapy combined with the use of radiofrequency ablation, radiation, and other therapies can achieve local tumor control, relieve pain, and main-tain normal neurological function. Thus, the quality of life of the patient is improved. Percutaneous vertebroplasty, radiofrequency abla-tion, spinal endoscopy, and other modern forms of minimally invasive surgery will have more applications in the treatment of spinal metastatic tumors.

OBJECTIVE To investigate the incidence,symtoms and prognosis of hospital infection by Mucor after liver transplantation.METHODS The clinical data of all the patients with complicated hospital infection orthotopic by Mucor after orthotopic liver transplantation were analyzed restrospectively.RESULTS There were 9 cases with complicated hospital infection by Mucor from in 750 liver transplant recipients.Seven cases developed superficial incisional infection with delayed healing and rapid increased secretion on the surface of incisions.All of them recovered after antifungal therapy.Two cases had pulmonary Mucor infection combined with bacteria and died of multi-organ failure.CONCLUSIONS The incidence of hospital infection by Mucor in liver transplant recipients is about 1%.The most common symtoms are superficial incisional infection and the patients recover well.However,the cases with complicated pulmonary Mucor infection are difficult to treat and have a poor prognosis.

Anemia, Hemolytic ; complications ; Child ; Humans ; Pneumonia ; complications

Objective To explore the influence of IFN-? on anti-proliferation and apoptosis of the Caspase-8 silenced neuroblastoma cell line induced by doxorubicin and the influence mechanism.Methods MTT and flow cytometric analysis were used to detect the survival and apoptosis rates before and after the combined treatment of IFN-? and doxorubicin.Immunohistochemical staining was used to detect the expression of caspase-8 protein before and after the treatment of IFN-?.Results The survival rates of doxorubicin(0.03,0.10,0.30?g/ml)used alone for 24h were(95.62?13.03)%,(82.62?7.94)%,(64.84?9.19)%,IFN-?(10,100,1000U/ml)used alone for 48h were(98.37%?11.25)%,(97.15?5.36)%,(98.84?7.41)%.The survival rates of IFN-?(1000U/ml)combined with different concentration of doxorubicin(0.03,0.10,0.30?g/ml)were significantly lower than that of doxorubicin(0.03,0.10,0.30?g/ml)alone.The apoptosis rate of doxorubicin(0.30?g/ml)alone was(22.00?6.55)%,IFN-?(1000U/ml)alone was (8.22?4.00)%,whereas the apoptosis rate of the combined treatment of IFN-? and doxorubicin wassignificantly higher than that of doxorubicin alone;Immunohistochemical staining showed that caspase-8 protein was negative in SH-SY5Y cell line,whereas it become positiveafter the treatment of IFN-?(1000U/ml)for 48h.Conclusion Treating human neuroblastoma cell line SH-SY5Y cell with doxorubicin may induce anti-proliferation and apoptosis.Combined treatment with IFN-? may significantly increase this effect.The mechanism may be realized by upregulating the expression of caspase-8 protein.

The circadian levels of norepinephrine ( NE ) and dopamiae (DA) in the whole brain were determined spectrofluorometrically in control mice and in mice pretreated with ginseng saponin. All animals were adapted for a minimum period of 2 weeks to an environmental room equipped with, an automatically timed 12h-light and 12h-dark illumination cycle before experiment. Data obtained at 4 h intervals for 48h spans were analyzed by the mean cosinor method.It has been proved that the catecholamine concentrations in the brain vary diurnally. The whole brain NE and DA contents were highest during the middle of dark phase and decreased to a low levels after the onset of light phase. In administration of ginseng saponin altered the circadian pattern and ( or ) levels of brain catecholamine over controls. In order to check the above results reserpine was injected to mice. The levels of NE and DA remarkedly depleted at the times studied, and they showed a significant circadian rhythms as well.It seems that ginseng saponin selectively modulates the circadian variations of brain NE and DA, and its effects may be as a cosinor function of the time of day.

17 Cheqiancao produced in China were identified by UV spectrophotometry. The differences of their UV spectra were listed.