Objective To observe the clinical effect of Qushi Hua yu Tongluo Formu la (Prescriptions for dissolving damp, removing stasis, and eliminating obstruct ion of meridians) on hyperuricemia complicated with diabetes. Methods Totally 60 patients were randomized into a treatment group and a control gr oup with 30 in each. The control group was administered Gliquidone 30mg, three t imes a day, while the treatment group was added Qushi Huayu Tongluo F ormula, one dosage per day. Both groups were treated for 90 days. The clinical e ffect and the changes in serum uric acid, renal functions, blood lipid, and gly cosylated hemoglobin of both groups were observed. Results The total effective rate of the treatment groups and control groups was 93.34% and 23.33% respectiv ely, the difference was significant (P