1.GT-4A workstation for pain relief during labor
Chinese Journal of Perinatal Medicine 2000;0(04):-
Objective To investigate the effect of different analgesia during labor and their side effect to the neonates. Methods Totally 130 puerperas were randomly divided into three groups: group A included 50 puerperas with analgesia by GT-4A workstation; group B included of 40 puerperas with mixed gas analgesia consisted of 50% of nitric oxide and 50% of oxygen; and group C(40 gravidas) as control group. The analgesic effect, duration of labor, mode of delivery and the amount of postpartum hemorrhage were observed. Results The analgesic effect in group A was significantly better than group B ( P
2.Study of the relationship between fasting blood glucose and islet ? cell function
Aihong FAN ; Yan CHEN ; Shandong YE
Chinese Journal of Diabetes 1994;0(03):-
411 subjects were divided into six groups according to their FPG levels.And OGTT was carried out.Result showed that along with the FPG increasing, HOMA ?-cell index and ?I30 /?G30 were decreased progressively, and the fasting serum proinsulin level and ratio of proinsulin /insulin were increased markedly.The area under insulin curve decreased gradually when FPG was above 8 mmol/L. In conclusion, FPG is a reflection of islet ? cell function.
3.Effect of rosiglitazone on expression and excretion of connective tissue growth factor in renal tissue and urinary of diabetic rats
Wei CHEN ; Shandong YE ; Yingxin WANG ; Wen HU ; Aihong FAN ; Yan CHEN ; Guangwei YANG ; Xiucai LI
Chinese Pharmacological Bulletin 2003;0(09):-
Aim To study the effect of rosiglitazone(RGZ)on expression and excretion of connective tissue growth factor(CTGF) in renal tissue and urinary of diabetic nephropathy rats.Methods Three groups of rats were studied:normal control group(n=8),STZ-induced diabetic model group(n=8),diabetes RGZ-treatment group(n=8).Urinary CTGF was measured at the 1 st,4 th,6 th and 8 th week,as well as the expressions of CTGF protein(by histochemical staining)at the 8 th week by ELISA.Results The urinary excretion rates of CTGF at 4 th、6 th、8 th weeks and the expressions of CTGF protein in renal cortex at 8th weeks significantly increased in STZ-induced model group compared with those in normal group(P
4.Effect of Danzhi Jiangtang Capsule Combined with Atorvastatin on Intima-media Thickness in Diabetes Patients without Hypertension
Zhaohui FANG ; Jindong ZHAO ; Jinping WANG ; Yunfei NIU ; Yiqiong SHU ; Aihong YUAN ; Qian WU ; Qingyun FAN ; Jian LIU ; Taotao BAO ; Yuan LUO ; Ruimin LU ; Chenglin GUO ; Ting JIANG ; Liqun CUI ; Hui YANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(5):884-890
This study was aimed to observe the curative effect and safety of Danzhi Jiangtang Capsule ( DJC ) combined with atorvastatin on carotid artery intima-media thickness (IMT) in diabetes patients without hyper-tension . A total of 196 diabetes patients without hypertension with incrassate carotid artery IMT were randomly divided into the control group ( 98 cases ) and the treatment group ( 98 cases ) . The conventional diabetes thera-py was given to both groups . The atorvastatin of 20 mg/night was given to the control group . And the atorvas-tatin 20 mg/night added with DJC 9 . 0 g/night were given to the treatment group . The treatment course was
12 months . Carotid artery IMT , carotid atherosclerotic plaque area , FPG , FIns , HOMA-IR , HbA1c , blood lipids , hepatorenal function and etc . were examined before and after the treatment respectively . The results showed that there was a significant positive correlation between carotid artery IMT and FIns , HOMA-IR , HbAlc , LDL-C . After 12-month treatment , the total effectiveness is 85 . 87% in the treatment group . And there was significant difference compared with the control group ( P < 0 . 05 ) . The levels of FPG , FIns , HOMA-IR , HbAlc of the treatment group had no difference compared with the control group . Compared with the control group, TC and LDL-C of the treatment group was obviously decreased (P < 0.05). And HDL-C was significantly increased ( P < 0 . 05 ) . The carotid artery IMT of the treatment group decreased from ( 0 . 11 ±0 . 01 ) cm to ( 0 . 08 ± 0 . 01 ) cm . And compared with the control group , there was statistical significance ( P <0 . 05 ) . The carotid atherosclerotic plaque area of 58 cases in the treatment group decreased from ( 0 . 37 ±0.56) cm2 to (0.21 ± 0.25) cm2. However, there was no statistical significance compared to the control group. There were 5 adverse events in the control group and 9 adverse events in the treatment group . And there was no difference between two groups. It was concluded that DJC combined with atorvastatin can regulate lipid metabolism and reduce carotid artery IMT .