BACKGROUND:Digit ratio is basical y determined within the first 3 months of fetal development. Digit and digit ratio exhibit differences between genders and between left and right hands. Nationality, regional and ethnic difference may also influence the digit ratio. So far, there is no report about the digit ratio of Kazakh adults. OBJECTIVE:To study the characteristics of digit ratio of young Kazakh nationality in Xinjiang of China. METHODS:A total of 200 young Kazakh volunteers in Xinjiang, aged 18-25 years, were enrol ed, including 100 males and 100 females. These participants were subjected to posteroanterior X-ray of both hands. Phalanx length and body height were measured, and the resulting data were statistical y analyzed using SPSS19.0 software. RESULTS AND CONCLUSION:The digit ratio of Xinjiang Kazakh people was 3D>4D>2D>5D. Male digit ratio possessed the tendency of 3D:5D>4D:5D>2D:5D>3D:4D>3D:4D>2D:3D>2D:4D;female digit ratio possessed the tendency of 3D:5D>2D:5D>3D:4D>4D:5D>2D:4D>2D:3D. The digit ratio of 2D:3D, 3D:4D, 4D:5D was higher in the male than the female;the digit ratio of 2D:4D, 2D:5D, 3D:5D was higher in the female than the male. Digit ratio had sexual differences, especial y in 3D:5D (P<0.05), and had bilateral differences, especial y in 2D:4D and 4D:5D (P<0.05). These findings indicate that the digit ratio of Xinjiang Kazakh people exhibits a bilateral difference, especial y in 2D:4D and 4D:5D, as wel as a sexual difference, especial y in 3D:5D .

Objective To study the sex difference and discriminating formulas by measuring both metacarpal bones on X-ray and body height of Kazakh nationality adults,providing anatomical data for physical anthropology and forensic medicine. Methods The metacarpal bones length on X-ray films and body height from 200 adults of Kazakh nationality,including 100 male and 100 females were measured. The obtained date were statistically dealt by SPSS15.0 software. Results The length of the 4th metacarpal bone in male and the 5th in female were statistical significance beside, 4 discriminating formulas were obtained as follows: Y＝2.824r_1+2.563r_4-0.654r_5+0.614l7-0.039l_9+2.452l_(10)-212.186,Y＝2.350r_1+2.377r_4-0.995r_5+0.445l_7+0.046l_9+2.966l_(10)-191.622,Y＝0.393h_1+3.152r_1+0.435r_5+1.250r_(10)-463.734,Y＝0.362h_1+2.785r_1+0.028r_5+1.834 r_(10)-404.748, the accuracy being 89.67%、86.55%、90.00% and 87.50%. Conclusion The data presented in this paper indicates that the body height of male and female kazakh minority is closely related with the enlargement of their metacarpal bones.

Objective To investigate the roles of adrenomedullin(ADM) and endothelin-1(ET-1) in left-to-right shunt congenital heart disease(CHD) complicated with congestive heart failure(CHF).Methods Plasma ADM and ET-1 concentrations were measured by radioimmunoassay in heart failure stage and recovery period of 18 infants with left-to-right shunt CHD.Also 20 healthy infants acted as control group were measured.Results Plasma concentrations of ADM and EF-1 were significantly higher in heart failure stage of left-to-right CHD infants than those in their recovery period,and both in their heart failure stage and in their recovery period were higher than that in control group(P

OBJECTIVETo explore the association of 8-hydroxyguanine glycosidase OGG1 Ser326Cys polymorphism with semen quality and the risk of male infertility.

METHODSThis case-control study included 620 idiopathic infertile patients and 385 normal fertile controls. We determined their genotypes by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and analyzed their semen quality by computer-aided semen analysis (CASA).

RESULTSThe individuals with OGG1 326 Cys/Cys showed significantly lower sperm motility and concentration ([52.1 +/- 26.7]% and (3.75 +/- 0.91) x 10(6)/ml, ln transformed value) than the Ser/Ser carriers ([59.0 +/- 21.8] % and (4.12 +/- 0.88) x 10(6)/ml, ln transformed value) (P < 0.05). The risk of male infertility increased 69% in the OGG1 326Cys allele carriers as compared with the Ser carriers (OR = 1.69, 95% CI: 1.24 -2.31).

CONCLUSIONOGG1 326 Ser/Cys polymorphism might contribute to the risk of male infertility in the southern Chinese population.

Adult ; Case-Control Studies ; DNA Glycosylases ; genetics ; Genotype ; Humans ; Infertility, Male ; genetics ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Semen Analysis ; Young Adult

OBJECTIVEThe literature published in West China Journal of Stomatology (WCJS) cited by science periodical from 1983 to 2001 were analyzed to evaluate the academic level and quality of WCJS.

METHODSThe cited literature was searched by Chinese biological medical disc (CBMDisc) from 1983 to 2001. The distributions of the times, the periodical and the authors were described.

RESULTSThe quantities of cited literature were 1 338 and increased with years. The periodical and the authors were 266 and 1 003 respectively from 1998 to 2001. The cited frequencies of stomatological periodicals were more than that of other academic periodical. The authors scattered in 32 provinces and 448 units of China. The medical university and affiliated hospital were 32.14%, the local hospital and stomatological dispensary were 54.69%, the military hospital was 10.71%, and other unit was 2.46%.

CONCLUSIONThe literature published in WCJS are superior in quality. The cited frequency of WCJS is high relatively. WCJS is one of the most important informational source of stomatology.

Bibliometrics ; China ; Hospitals ; Humans ; Oral Medicine ; Publishing ; trends ; Schools, Medical ; Universities

In this study, the general bacterial probe and specific cellulolytic bacterial probes were used to quantify the bacteria in rumen. The total RNA were extracted and then hybridized with general bacterial probe after a dilution of concentration. The result showed that there was a high correlation between the hybridization signal and the dilution of total bacterial RNA. Based on the result above, the quantities of three cellulolytic bacteria in rumen sample were detected. The comparative RNA percentage of three cellulolytic bacteria to total bacterial RNA were similar to the previous reports. It can be concluded that the quantification of bacteria in rumen could be conducted by this approach, and which could be used in future research.

The recombinant fusion protein staphylokinase-hirudin(rSFH) was purified from the high density-fermented engineered E.coli by means of ion-exchange chromatography (IEC) and gel filtration (GF). The purity of rSFH reached to more than 98% determined by RP-HPLC and SDS-PAGE, and the yield was up to 0.7g per liter of fermentation broth. The analysis of homologous dimmer of rSFH appeared during the purification and calculation of the surface hydrophobic area had been carried out by means of hydrophobic chromatography and MALD-TOF. The influence of sodium chloride and temperature on the behavior of rSFH reversible dimerization was analyzed by high performance sized- exclusive chromatography(HPSEC). It is concluded that the hydrophobic interaction played an important role in the reversible dimerization of rSFH.

AIM:To study the effect of berberin hydrochloride(Ber)on the elevation of blood concentra- tion of Cyclosporin A(CsA)and liver and renal functions in renal transplanted recipients.METHODS:138 cases with renal transplantation in experimental group were treated with CsA and Ber and 150 cases with renal trans- plantation in control group received CsA only.Blood lev- els of CsA,biochemistry indexes for liver and renal func- tion were determined.RESULTS:After 1,3,6 months combined with Ber,blood concentrations of CsA in pa- tients went up by 49.8%,81.4%,36.9% and the radios of blood concentration of CsA to CsA dosage increased 88.8%,102.0%,72.5% compared with those before taking Ber(P

Objective To summarize the experience of surgery for hypertensive intraventricular hemorrhage with self-made neuroendoscope-assisted equipments. Methods Twenty-two patients with ventricular hemorrhage, admitted to our hospital from January 2006 to May 2009, were chosen; surgery with self-made neuroendoscope-assisted equipments was performed on them. Results CT 24 h after the surgery showed that the clearance rate of intraventrieular hematoma was higher than 90% (median 92.7%). No hydrocephalus, postoperative intracranial infection or secondary hemorrhage appeared in all the patients. All patients were followed up for 6 months. According to GOS, the result was excellent in 9 patients, good in 8, fare in 3, poor in 1 and dead in 1. Conclusion Endoscopic surgery for ventricular hemorrhage with self-made neuroendoscope-assisted equipments is minimally invasive and effective with direct-vision, low complication and effective hemorrhage evacuation;it also improves good neurological outcomes.

Objective To evaluate the efficacy and adverse effects of gefitinib in the treatment of fe- male patients with advanced adenocarcinoma of lung who had failed to previous chemotherapy.Methods These patients received 250mg of gefitinib orally,once daily until disease progression or development of intol- erable toxic reaction.They were evaluated one month after treatment and every other month thereafter.Results Among the 27 evaluable patients,there were 1 CR(3.7%),11 PR(40.8%),10 SD(37.0%)and 5 PD(18.5%). The overall response rate was 44.5%(95% CI 29%～68%);and 22 patients(81.5%)gained profit(CR+PR+ SD)from the clinical therapy(95% CI 62%～94%);the mean TTP was 7.2 months.Symptomatic improvement rate was 80.0%.The main adverse effects were mild rash and diarrhea.Conclusion gefitinib has significant efficacy in the treatment of female patients with advanced tung cancer who had failed to previous chemother- apy.Adverse effects are mild.gefitinib is a suitable therapy for these patients.