This study was intended to develop food and nutrition cyberclass contents for nonmajor students at university. We investigated universities which offered food and nutrition related courses in 1998 by a telephone survey in order to select the most appropriate lecture contents for the nonmajor university students. We investigated to select the most needed lecture contents for the students, 15 questions on evaluation of cyberclasses which they took. The number of subjects were 140 students of 'C' university who registered for nonmajor food and nutrition course in 1998. Among 140 students, 80 were cyberclass students and 60 were non cyberclass students. The results of the survey were as following : Fifty-five universities out of 62 had curriculums on food and nutrition in 1998 and 36,802 students attended the non major food and nutrition lectures. 84.9% of the respondents had their own computes and the main application mostly used was word processing. Additionally, 33.3% of them used on-line communications and 81.4% of them used internet. The most interesting subject of the respondents was 'disease and nutrition management'. The male respondents were concerned more about 'alcohol and health', whereas the females were concerned about 'obesity and weight control'.
Curriculum ; Surveys and Questionnaires ; Female ; Humans ; Internet ; Lectures ; Male ; Telephone ; Word Processing

This study was to investigate the changes in nutrition knowledge, nutrition attitude and food habit during 'meal management and diet' course to nonmajor university students by questionnaires. 280 students of Chungnam university who registered nonmajor 'meal management and diet' course in the 2003 were the subjects. The results of this study are as follows. BMIs of male and female students were 21.5 and 19.3. According to BMI, underweight subjects were 24.3%, normal and overweight (danger & obesity) subjects were each 62.4% and 13.6%, respectively. The nutrition knowledge scores significantly (p < 0.001) increased from 12.1 to 14.0 after the lecture, and the uncertainty rate of nutrition knowledge decreased significantly. Also, there were no significant differences in nutrition attitude score (39.5 to 39.8 points). Female subjects showed significantly (p < 0.05) higher nutrition knowledge scores (12.3 points) than male (11.4 points). 20% of the subjects smoked and 82.9% had alcohol drinks and 24.4% exercised more than 3 times per week. The subjects who ate regular meals significantly increased from 9.3 to 12.5% after the lecture, and smoking subjects decreased from 20 to 13%, but alcohol drinking subjects did not changed significantly.
Alcohol Drinking ; Chungcheongnam-do ; Diet* ; Education* ; Female ; Food Habits ; Humans ; Male ; Meals ; Overweight ; Smoke ; Smoking ; Thinness ; Uncertainty ; Surveys and Questionnaires

BACKGROUND: Nutrition delivery is frequently interrupted or delayed by physicians' ordering patterns. We conducted this study to investigate the effect of physician compliance with tube feeding (TF) protocol on the nutritional and clinical outcomes in acute lung injury (ALI) patients. METHODS: After implementing a TF protocol, 71 ALI patients with mechanical ventilation (MV) for > or = 7 days were observed. A dietician assessed the nutritional status of the patients and established individualized nutrition plans according to the protocol. If the physicians followed the dietician's recommendation within 48 hours, the patients were classified under the compliant group (Group 1). RESULTS: Forty patients (56.3%) were classified into Group 1. Prealbumin was comparable in both groups at ICU admission but higher in Group 1 at the time of discharge from the ICU (228 +/- 81 vs 157 +/- 77 mg/dl, p = 0.025). Nitrogen balance was only improved in Group 1. The time to reach calorie goal was shorter and non-feeding days were reduced in Group 1. The proportion of parenteral nutrition to nutritional support days was lower and delivered calories on the 4th and 7th day of TF were higher in Group 1 (p < 0.001). ICU mortality/stay and hospital mortality failed to show differences but hospital stay was prolonged in the noncompliant group (Group 2) (p = 0.023). Arterial oxygen tension and PaO2/FiO2 were maintained during the 1st week of ICU stay in Group 1 but were decreased in Group 2. CONCLUSIONS: Physicians' compliance with the TF protocol contributed to the likelihood of nutritional improvement and a shorter hospital stay in ALI patients with prolonged MV.
Acute Lung Injury ; Compliance ; Enteral Nutrition ; Guideline Adherence ; Hospital Mortality ; Humans ; Length of Stay ; Nitrogen ; Nutritional Status ; Nutritional Support ; Oxygen ; Parenteral Nutrition ; Prealbumin ; Respiration, Artificial

PURPOSE: The purpose of this study was to investigate the effect of the development and application of the new nurses' core skill program on the clinical skill, confidence, knowledge and performance of new nurses. METHODS: This study was a nonequivalent control group post-test design on 46 new nurses with 3 to 6 months work experience in a general hospital. Data were collected from August 2015 to August 2016. A training program of core fundamental nursing skills was applied on 23 new nurses from 2016 in the experiment group, and an existing training method was applied on 23 new nurses from 2015 in the comparison group. The collected data were analyzed using SPSS/WIN 23.0. RESULTS: The experimental group (89±4.29) showed higher score in practical skill assessment compared to the control group (85.09±3.99) and showed a statistically significant difference (p<001). CONCLUSION: A training program of core fundamental nursing skills for new nurses proved effective in improving practical skills. Further research on the development of a systemic training program that can improve clinical nursing knowledge and work ability for new nurses according to the extended enforcement of a Nursing Care Integrated Service ward is needed.
Clinical Competence ; Education* ; Education, Nursing ; Hospitals, General ; Methods ; Nursing Care* ; Nursing*

A 51-year-old highly fit man presented for dyspnea with strenuous aerobic exercise. The patient was asymptomatic and all tests were normal at rest. With increasing exercise intensity, he suddenly complained of dyspnea and showed a severe exercise-induced hypoxemia with an excessive alveolar-arterial oxygen tension difference. In agitated saline contrast echocardiography at peak exercise, a large amount of left to right shunt was identified after > 5 cardiac cycles, which suggests the presence of exercise-induced intrapulmonary arteriovenous shunt in this patient.
Anoxia ; Dihydroergotamine ; Dyspnea* ; Echocardiography ; Exercise ; Humans ; Middle Aged ; Oxygen

Expression of estrogen receptors (ER)-alpha and -beta, as well as androgen receptor (AR), in hepatocellular carcinoma (HCC) is thought to be correlated with prognosis, survival, and male prevalence of HCC. These hypotheses are based on investigations of European patients; however the expression patterns of these receptors in Asian patients are largely unknown. In this study, we collected liver carcinoma and peritumor tissues from 32 patients (9 females and 23 males) in South Korea. The expression of ERs and ARs was studied using RT-PCR. Wild-type ER-alpha and AR were expressed in all of the samples investigated, and their expression was independent of the causal virus or patient sex. Expression of the ER-alpha variant was independent of sex (100% female vs. 91.3% male) and HCV and HBV status (91.3% vs. 100%). Wild-type ER-beta was expressed more often in HCV patients than in HBV patients (95.7% vs. 44.4%; p < 0.05). In conclusion, the stronger ER-alpha variant expression in HCC tissues implies that this variant has an important role in HCC development. However, at least in Korean patients, expression of the ER-alpha variant (vER-alpha) is not related to male HCC prevalence. In addition, the predominant expression of ER-beta in HCV patients suggests that it plays an important role in HCV-induced liver disease.
Sex Factors ; Receptors, Estrogen/*metabolism ; Receptors, Androgen/metabolism ; Middle Aged ; Male ; Liver Neoplasms/ethnology/*metabolism/virology ; Korea ; Humans ; Hepatitis B virus/isolation & purification ; Hepacivirus/isolation & purification ; Female ; Carcinoma, Hepatocellular/ethnology/*metabolism/virology ; Biological Markers/metabolism ; Asian Continental Ancestry Group ; Aged

Ras-related, estrogen-regulated, and growth-inhibitory gene (RERG) is a novel gene that was first reported in breast cancer. However, the functions of RERG are largely unknown in other tumor types. In this study, RERG expression was analyzed in hepatocellular carcinomas of human patients using reverse transcriptase PCR analysis. In addition, the possible regulation of RERG expression by histone deacetyltransferases (HDACs) was studied in several cell lines. Interestingly, the expression of RERG gene was increased in hepatocellular carcinoma (HCC) of male patients (57.9%) but decreased in HCC of females (87.5%) comparison with paired peri-tumoral tissues. Moreover, RERG gene expression was increased in murine hepatoma Hepa1-6 cells, human breast tumor MDA-MB-231 cells, and mouse normal fibroblast NIH3T3 cells after treated by HDAC inhibitor, trichostatin A. Our results suggest that RERG may function in a gender-dependent manner in hepatic tumorigenesis and that the expression of this gene may be regulated by an HDAC-related signaling pathway.
Signal Transduction ; Sex Factors ; Mice, Transgenic ; Mice, Inbred C57BL ; Mice ; Male ; Liver Neoplasms/*genetics ; Humans ; Histone Deacetylases/*physiology ; Hepatocytes/metabolism ; Growth Inhibitors/*genetics ; *Genes, ras ; *Gene Expression Regulation, Neoplastic ; Female ; Estrogens/*pharmacology ; Estrogen Receptor alpha/analysis ; Cell Proliferation ; Animals