1.Acute Pancreatitis and Gastroduodenal Intussusception Induced by an Underlying Gastric Gastrointestinal Stromal Tumor: A Case Report.
Mehmet Siddik YILDIZ ; Ahmet DOĞAN ; Ibrahim Halil KOPARAN ; Mehmet Emin ADIN
Journal of Gastric Cancer 2016;16(1):54-57
Gastrointestinal stromal tumors (GISTs) are rare tumors of the gastrointestinal system and comprise only 1% to 3% of all gastrointestinal tract tumors, with the majority of them arising in the stomach. In this report, we present the unique findings of a case of gastroduodenal intussusception caused by an underlying gastric GIST and complicated with severe acute pancreatitis.
Gastrointestinal Stromal Tumors*
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Gastrointestinal Tract
;
Intussusception*
;
Pancreatitis*
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Pancreatitis, Acute Necrotizing
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Stomach
2.Incomplete Isolated C7 Root Injury Caused by Gunshot Wound: A Case Report.
Ulvi CIFTÇI ; Ahmet Tolgay AKINCI ; Emre DELEN ; Doğan GÜÇLÜHAN
Korean Journal of Neurotrauma 2017;13(1):45-49
Gunshot wounds to the spine cause severe neurological and/or internal organs damages. Although most of publications in the literature are realized on military injuries, increased civilian arming which raises civilian gunshot injuries is a new social danger causing serious health problems. In gunshot injuries to the spine; vertebral column, spinal cord and nerve roots are damaged with direct, indirect and transient cavitation related mechanisms. In this case report, we present 24 years old male patient who had severe pain and monoparesis in left upper extremity followed by gunshot injury to the spine with clinical, radiological and postoperative follow-up findings.
Arm
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Cervical Vertebrae
;
Female
;
Follow-Up Studies
;
Humans
;
Male
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Military Personnel
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Paresis
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Radiculopathy
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Spinal Cord
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Spine
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Upper Extremity
;
Wounds, Gunshot*
3.Decreased Chitotriosidase Activity and Levels in Familial Mediterranean Fever.
Halef Okan DOĞAN ; Ahmet OMMA ; Turan TURHAN ; Nihal BOĞDAYCIOĞLU ; Yaşar KARAASLAN ; Hayrettin YAVUZ ; Ozlem DEMIRPENÇE ; Hüseyin AYDIN ; Sevtap BAKIR
Journal of Korean Medical Science 2016;31(12):1902-1906
Different studies have demonstrated changes in chitotriosidase (ChT) activity and concentrations in multiple diseases. However, changes in ChT activity and concentrations have not been concurrently evaluated in patients with Familial Mediterranean Fever (FMF). In this study, we analyzed the changes in serum ChT activity and concentrations in patients with FMF. The study included a total of 80 patients with FMF and 80 healthy controls. ChT enzyme activity and concentrations were measured and then compared between the groups. ChT activity was measured by using fluorometric ELISA and ChT concentrations were measured by using colorimetric ELISA methods. The median ChT activity was 10.00 (6.00–15.00) nmol/mL/hr in the patients and 14.00 (6.25–20.75) nmol/mL/hr in the controls. There was a statistically significant difference in the ChT activity between the controls and patients (P = 0.027). The median ChT concentrations were 65.40 (46.20–84.92) pg/mL and 125.00 (75.72–143.95) pg/mL in the patients and controls, respectively (P < 0.001), which were expressed as median percentiles (25th–75th). Additionally, we found no correlation between C-reactive protein and ChT activity (P = 0.978, r = 0.003) and concentrations (P = 0.446, r = −0.87). Serum ChT enzyme activity and concentrations may not be considered as a biomarker in FMF patients taking colchicine. New studies are needed to evaluate the changes of enzyme activity and concentration in colchicine-negative patients.
C-Reactive Protein
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Colchicine
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Enzyme-Linked Immunosorbent Assay
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Familial Mediterranean Fever*
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Humans
4.Endocan and Non-Dipping Circadian Pattern in Newly Diagnosed Essential Hypertension.
Tolga CIMEN ; Murat BILGIN ; Ahmet AKYEL ; Mehmet Ali FELEKOĞLU ; Ali NALLBANI ; Seyda OZDEMIR ; Gönül ERDEN ; Alpaslan OZTÜRK ; Mehmet DOĞAN ; Ekrem YETER
Korean Circulation Journal 2016;46(6):827-833
BACKGROUND AND OBJECTIVES: Non-dipper hypertension is frequently accompanied by endothelial dysfunction and activation. Previous studies suggested that endocan may be a novel endothelial dysfunction marker. This study aims to investigate the association between circadian blood pressure (BP) pattern and plasma endocan levels together with high-sensitivity C-reactive protein (hsCRP) in patients with newly diagnosed untreated hypertension. SUBJECTS AND METHODS: Twenty-four hour ambulatory blood pressure monitoring was recorded in 35 dipper, 35 non-dipper hypertensives and 35 healthy controls. Endocan levels were measured by enzyme-linked immunosorbent assay. Serum levels of hsCRP were also recorded. RESULTS: Despite similar daytime and 24-hour average BP values between dippers and non-dippers, statistically significant high nocturnal BP was accompanied by a non-dipping pattern (Systolic BP: 132±9 vs. 147±11 mmHg; Distolic BP: 80±7 vs. 91±9 mmHg, respectively, p<0.001 for both). Non-dipper patients demonstrated higher endocan levels compared to dippers and normotensives (367 (193-844) pg/mL, 254 (182-512) pg/mL and 237 (141-314) pg/ml, respectively, p<0.001). HsCRP levels were significantly higher in non-dippers than the other groups (p=0.013). In a multivariate logistic regression analysis, endocan (p=0.021) and hsCRP (p=0.044) were independently associated with a non-dipping pattern. CONCLUSION: Elevated endocan levels were found in non-dipper groups. Endocan and hsCRP were found to be independently associated with a non-dipping pattern. We suggest that elevated levels of endocan in non-dipper hypertensive patients might be associated with a longer duration of exposure to high BP. These results point to the possible future role of endocan in selection of hypertensive patients at higher risk or target organ damage.
Blood Pressure
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Blood Pressure Monitoring, Ambulatory
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C-Reactive Protein
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Enzyme-Linked Immunosorbent Assay
;
Humans
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Hypertension*
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Logistic Models
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Plasma