No abstract available.
Birth Rate* ; Maternal Age* ; Parturition*

No abstract available.
Pregnancy, High-Risk* ; Rheology* ; Umbilical Arteries*

No abstract available.
Carcinoma, Squamous Cell* ; Female ; Ovary*

No abstract available.
Blood Flow Velocity* ; Pregnancy* ; Umbilical Arteries*

No abstract available.
Aorta, Thoracic* ; Blood Flow Velocity* ; Pregnancy*

No abstract available.
Adenocarcinoma*

We report a case of non-traumatic rhabdomyolysis after overdose of doxylamine succinate. A 22-year-old woman with reactive depression had an overdose of doxylamine with suicidal intent. She had decreased mental state, confusion, convulsion, vomiting, tachycardia, pupil dilatation, and ocular flutter. Serum creatine phosphokinase concentra-tion was 6,752 IU/L initially, increased to maximum (165,590 IU/L) at the third day, and then rapidly decreased and returned to normal 2 weeks after intoxication. Acute renal failure occurred but was resolved without hemodialysis. Rhabdomyolysis associated with renal failure is a rare but serious complication after doxylamine overdose.
Acute Kidney Injury ; Adjustment Disorders ; Creatine Kinase ; Dilatation ; Doxylamine* ; Female ; Humans ; Pupil ; Renal Dialysis ; Renal Insufficiency ; Rhabdomyolysis* ; Seizures ; Succinic Acid ; Tachycardia ; Vomiting ; Young Adult

OBJECTIVE: The changes of the production of nitric oxide in preeclampsia are still controversial. To determine the changes of nitric oxide production in preeclamptic pregnancies, NOS activity and eNOS and iNOS expression in preeclamptic placentae were compared with those in normal placentae, and to determine the changes of nitirc oxide production according to the sites of placenta, NOS activity and eNOS expression in preeclamptic placentae were also compared with those in normal placentae. METHODS: Human placentae were obtained from 15 normal and 15 preeclamptic pregnant women at the time of cesarean section. NOS activity was assessed by measuring the conversion of [3H]-arginine into [3H]-citrulline. The eNOS and iNOS expression were assessed by using western blot analysis. Data were analyzed by Student t-test and paired t-test where appropriate. RESULTS: The NOS activity(judged by measurement of [3H]-citrulline production) was significantly increased in preeclamptic placentae compared to normal(P<0.05). In normal and preeclamptic pregnant placentae, the NOS activity in main stem villi was increased compared to that in terminal villi. However, the difference of NOS activity between main stem villi and terminal villi was not significant(P>0.05). Quantification of the autoradiographic images demonstrated that the integrated optical density of the immunoreactive bands of eNOS were significantly lower in preeclamptic placentae compared to normal(p<0.05). Conversely, the integrated optical densities of the bands of iNOS were significantly higher in preeclamptic placentae compared to normal(p<0.05). CONCLUSIONS: Although the eNOS expression in preeclamptic placentae was lower than that in normal placentae, the NOS activity was significantly higher in preeclamptic placentae than that in normal in this study. These are result from increased production of iNOS in the compensatory mechanisms for the decreased nitric oxide production in pre-eclamptic placentae.
Blotting, Western ; Cesarean Section ; Female ; Humans* ; Nitric Oxide Synthase* ; Nitric Oxide* ; Placenta* ; Pre-Eclampsia ; Pregnancy* ; Pregnant Women

Precise prenatal care and safe childbirth under the guidance of a qualified obstetrician are essential reproductive healthcare services that enhance the survival and wellbeing of mothers and newborns. However, during recent decades many maternity hospitals and clinics in Korea have closed, particularly those in rural areas. In addition, the number of obstetricians providing care for pregnant women is declining. This reduction in obstetric services is a growing political issue in Korea. Several policies and programs have tried to accelerate and expand the provision of essential maternity services, especially in rural areas, but there have been numerous barriers to overcome, including malpractice litigations. Now is the time to discuss the role of current and future government programs in the improvement of obstetric care and, moreover, to develop outlines for progress in underserved areas.
Delivery of Health Care ; Female ; Government Programs ; Hospitals, Maternity ; Humans ; Infant, Newborn ; Jurisprudence ; Korea* ; Malpractice ; Mothers ; Parturition* ; Politics ; Pregnancy ; Pregnant Women ; Prenatal Care

Despite recent improvements in the intensive care for postpartum hemorrhage, it remains one of the leading causes of maternal mortality and morbidity for obstetricians. Because it is difficult to prevent or predict postpartum hemorrhage, it is important to manage any such patients correctly and promptly. Management of postpartum hemorrhage may vary greatly among patients, depending on the etiology of the bleeding, available treatment options, and the patient's desire for future fertility. When managing postpartum hemorrhage, it is necessary to balance the use of conservative management with the need to control the bleeding and achieve hemostasis. Uterine massage and compression, and the administration of uterotonics such as oxytocin, ergometrine, and prostaglandins are primary, conservative, and noninvasive management techniques for patients with postpartum hemorrhage. Relatively noninvasive procedures such as curettage of remnant tissues, vaginal packing, repair of laceration, and percutaneous angiographic embolization can also be performed. In cases where these management techniques fail, surgical alternatives such as uterine or internal iliac artery ligation, uterine compression sutures, or hystrectomy are used. Surgical treatment of postpartum bleeding, performed as an appropriate and timely intervention, is life-saving. The management of postpartum bleeding requires a multidisciplinary approach with timely and efficient communication between clinical specialists and preserving fertility.
Critical Care ; Curettage ; Ergonovine ; Fertility ; Hemorrhage ; Hemostasis ; Humans ; Iliac Artery ; Lacerations ; Ligation ; Massage ; Maternal Mortality ; Oxytocin ; Postpartum Hemorrhage* ; Postpartum Period* ; Prostaglandins ; Specialization ; Sutures