1.Postinfectious Guillain-Barre syndrome in a patient with methimazole-induced agranulocytosis.
Yoon Young CHO ; Ji Young JOUNG ; Hyemin JEONG ; Dongmo JE ; Yun Soo HONG ; Sunghwan SUH ; Sun Wook KIM
The Korean Journal of Internal Medicine 2013;28(6):724-727
Both Graves disease and Guillain-Barre syndrome (GBS) are autoimmune disorders caused by impaired self-tolerance mechanisms and triggered by interactions between genetic and environmental factors. GBS in patients who suffer from other autoimmune diseases is rarely reported, and the development of postinfectious GBS in a patient with Graves disease has not been previously reported in the literature. Herein, we report a patient with Graves disease who developed postinfectious GBS during a course of methimazole-induced agranulocytosis.
Agranulocytosis/*chemically induced/diagnosis/therapy
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Antithyroid Agents/*adverse effects
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Female
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Graves Disease/diagnosis/*drug therapy
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Guillain-Barre Syndrome/diagnosis/*etiology/therapy
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Humans
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Immunoglobulins, Intravenous/therapeutic use
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Methimazole/*adverse effects
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Middle Aged
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Opportunistic Infections/diagnosis/*etiology/therapy
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Thyroidectomy
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Treatment Outcome